Illinois is currently home to 2635 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Understanding How Powered Componentry Impacts K2-Level Transfemoral Amputee Gait
NCT06433648
Recruiting
The goal of this study is to understand how providing power at the knee or ankle individually, or providing power at both the knee and ankle, impacts ambulation for K2 level transfemoral amputees. Aim 1: measure functional performance of K2 level ambulators when using a commercially available passive microprocessor knee prosthesis (Ottobock Cleg/Ottobock foot) or a powered knee and ankle prosthesis (SRALab Hybrid Knee and SRAlab Polycentric Powered Ankle. Aim 2: Participants will be evaluated... Read More
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/28/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Amputation, Amputation, Traumatic, Amputation of Knee, Amputation; Traumatic, Limb
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Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion
NCT06123026
Recruiting
The goal of this clinical trial is to compare breast symptoms (lactation, engorgement, etc) of individuals who undergo a procedure for second trimester of pregnancy loss between 16 weeks and 20 weeks gestational age. The participants will be randomly placed in two groups, one with a placebo tablet and one with medication called "cabergoline" which are taken immediately after their procedure. Researchers will compare groups to see if there are any significant differences in breast symptoms.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
05/28/2024
Locations: Northwestern Medical Center, Chicago, Illinois
Conditions: Lactation Suppressed, Second Trimester Abortion
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Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Exercise Performance
NCT06425939
Recruiting
Heart rate variability (HRV) is a measure of the variation in time between each heartbeat. It is an indirect and ubiquitous biomarker of performance readiness and recovery measured by most consumer-grade wearable fitness trackers. However, there is little documented on the relationship between HRV, training load, and performance measures in the Real-World. Whoop wrist-worn activity trackers have been validated against the gold-standard Electrocardiography (ECG) for HRV and HR measurements. Who... Read More
Gender:
ALL
Ages:
Between 25 years and 50 years
Trial Updated:
05/24/2024
Locations: PepsiCo R&D, Gatorade Sports Science Institute, Chicago, Illinois
Conditions: Heart Rate Variability, Exercise
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Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
ALL
Ages:
All
Trial Updated:
05/24/2024
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
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GI Oxalate Absorption
NCT05356000
Recruiting
This study aims to learn more about how oxalate, a compound found in many foods, may affect a person's chances of forming kidney stones. Active participation in this study will last for around one week. For the first two days, subjects will be asked to eat a special diet at home. From Days 3-5, they will eat special meals delivered to their home from a research clinic at the University of Chicago. They will also collect 24-hour urine samples at home on Days 4 and 5. On Day 6, they will come in... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/23/2024
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Bariatric Surgery Candidate, Kidney Stone
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HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
NCT04904588
Recruiting
This is a prospective, multi-center, Phase II study of hematopoietic cell transplantation (HCT) using human leukocyte antigen (HLA)-mismatched unrelated donors (MMUD) for peripheral blood stem cell transplant in adults and bone marrow stem cell transplant in children. Post-transplant cyclophosphamide (PTCy), tacrolimus and mycophenolate mofetil (MMF) will be used for for graft versus host disease (GVHD) prophylaxis. This trial will study how well this treatment works in patients with hematologic... Read More
Gender:
ALL
Ages:
1 year and above
Trial Updated:
05/22/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Lymphoma
Register for Updates
Promoting Genetic Counseling Among African American Women With a Family History of Breast Cancer
NCT04378751
Recruiting
In the United States, carriers of hereditary genetic mutations have up to an 85% risk of developing breast cancer compared to 12% in the general population. Overall uptake of genetic services is generally low, particularly among high-risk African American (AA) women, who carry a disproportionate burden of breast cancer mortality. Further, although testing close relatives of individuals who test positive for a pathogenic variant might curtail breast cancer disparities attributable to hereditary r... Read More
Gender:
FEMALE
Ages:
25 years and above
Trial Updated:
05/21/2024
Locations: UIC Cancer Center, Chicago, Illinois
Conditions: High Risk for Breast Cancer
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Clinical Data Registry of Amblyopia Patients on Luminopia Treatment
NCT06429280
Recruiting
Amblyopia is the most prevalent cause of reduced monocular visual acuity in children and young adults, with estimates of prevalence ranging from 1% to 5%. The most common associated amblyogenic risk factors are uncorrected anisometropia, strabismus, or a combination of these. In addition to reduced visual acuity, amblyopic patients may also have measurable dysfunction of accommodation, fixation, binocularity, vergence, reading fluency, depth perception, and contrast sensitivity. For the first t... Read More
Gender:
ALL
Ages:
All
Trial Updated:
05/20/2024
Locations: Lurie Children's Hospital, Chicago, Illinois
Conditions: Amblyopia
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Intuitive Control of a Hybrid Prosthetic Leg During Ambulation
NCT04038151
Recruiting
The objective of this research is to determine the clinical benefits of an innovative and lightweight powered leg controlled using our intent recognition framework in laboratory and community environments.
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/16/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Amputation
Register for Updates
Effectiveness Trial of Mobile ESI for Toddlers With Autism Identified by Early Screening in Primary Care
NCT05456139
Recruiting
The goal of this collaborative R01 is to demonstrate the therapeutic value and community-wide implementability of an early intervention (EI) platform for toddlers with autism spectrum disorder (ASD) that is completely virtual, from recruitment through intervention. This platform-Early Social Interaction Mobile Coaching (ESI-MC) deploys individual telehealth sessions with coaching and feedback to help families embed intervention in everyday activities. Specifically, the investigators will conduct... Read More
Gender:
ALL
Ages:
Between 15 months and 20 months
Trial Updated:
05/15/2024
Locations: Rush University, Chicago, Illinois
Conditions: Autism Spectrum Disorder
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Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years
NCT04373564
Recruiting
This study is a postmarketing requirement jointly carried out by four NDA holders (Bayer AG, Bracco, GE Healthcare and Guerbet) and the CRO IQVIA. The study aims to create detailed images of the organs and tissue of the human body during x-ray, CT-scan or MRI investigations, doctors are using contrast media (a kind of dye) which can be given to patients by injection into a blood vessel or by mouth. In this study researchers want to find out whether so called gadolinium-based contrast agents (G... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
05/15/2024
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Motor Function, Cognitive Function, Contrast Media
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The Role of Mechanical Diagnosis and Therapy in the Management of Concussion
NCT05859815
Recruiting
The purpose of this study is to examine the role of a Mechanical Diagnosis and Therapy (MDT) examination in identifying participants diagnosed with concussion who display a directional preference compared to who don't display a directional preference.
Gender:
ALL
Ages:
Between 13 years and 65 years
Trial Updated:
05/14/2024
Locations: Goodlife Physical Therapy, Orland Park, Illinois
Conditions: Brain Concussion, Mild Traumatic Brain Injury
Register for Updates