Illinois is currently home to 2644 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Illinois United ePREP Program Evaluation
NCT04378309
Recruiting
The current research is designed to implement and evaluate the ePREP relationship intervention with couples throughout the state of Illinois.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2021
Locations: University of Illinois Extension, Urbana, Illinois
Conditions: Relationship, Marital, Relational Problems
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Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML
NCT03250338
Recruiting
This is a randomized, multi-center, double-blind, placebo-controlled study designed to evaluate the efficacy of crenolanib administered following salvage chemotherapy, consolidation chemotherapy, post bone marrow transplantation and as maintenance in relapsed/refractory AML subjects with FLT3 activating mutation.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/28/2021
Locations: University of Chicago, Chicago, Illinois
Conditions: Relapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating Mutations
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Efficacy and Safety of Oral Rifaximin in Patients With Active Microscopic Colitis
NCT04043897
Recruiting
This is an open label study looking at rifaximin therapy for the treatment of microscopic (collagenous or lymphocytic) colitis.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/14/2021
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: Microscopic Colitis
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Effects of Lutein Supplementation on Cognition and MPOD in Multiple Sclerosis Patients-
NCT04843813
Recruiting
The central hypothesis is that lutein supplementation will improve MPOD and cognition. Accordingly, the specific aims are to 1) to determine the process feasibility associated with participating in 4-month lutein supplementation trial; and 2) to investigate the scientific feasibility of 4-month daily lutein supplementation on biological markers of lutein status and cognitive function among persons with MS.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
04/12/2021
Locations: University of Illinois at Urbana-Champaign, Urbana, Illinois
Conditions: Multiple Sclerosis
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An Amniotic Membrane Injection Comparing Two Doses (1 mL and 2 mL Injection) and a Placebo (Sterile Saline) in the Treatment of Osteoarthritis of the Knee
NCT04612023
Recruiting
The purpose of this study is to determine the dose effect of a single injectable acellular amniotic membrane derived allograft for the treatment of knee osteoarthritis and to confirm whether the use of 2 mL of the same amniotic injection offers a statistically significant advantage over the 1 mL injection when compared to a placebo.
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
02/10/2021
Locations: ICORE, Westmont, Illinois
Conditions: Osteoarthritis, Knee
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Positive Pressure Treadmill Walking for Individuals With Knee Pathology
NCT04747444
Recruiting
Our goal is to compare the serum biomarker changes of joint disease that occur in response to partially off-loaded (50%) walking exercise to regular (100%) walking exercise while on a Lower Body Positive Pressure (LBPP) treadmill. Secondly we are determining the relationship between changes in the concentration of these serum biomarkers and participant reported knee pain while walking on a LBPP treadmill.
Gender:
All
Ages:
50 years and above
Trial Updated:
02/06/2021
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Knee Osteoarthritis
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Low Cost Socket for Lower Limb Amputees
NCT04725461
Recruiting
The purpose of this research is to test an investigational fabrication system for transtibial prostheses. This fabrication method will be tested for comfort and function to determine feasibility of use for amputees in developing countries. To address the need for high quality and affordable prosthetic technology in developing countries, the investigators have developed a simplified socket fitting protocol using expandable rigid foam. The foam is formed by mixing small amounts of two liquid comp... Read More
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
01/22/2021
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Amputation, Amputation; Traumatic, Limb, Amputation, Traumatic
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Evaluating Wearable Smart Sensors for Continuous Measurement of Vital Signs in ICU Patients
NCT04723654
Recruiting
The purpose of this study is to develop biocompatible wireless electronic devices that will allow continuous, non-invasive hemodynamic and physiology measurements in the ICU.
Gender:
All
Ages:
18 years and below
Trial Updated:
01/20/2021
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Prematurity
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An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
NCT04718818
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Gurnee, Illinois
Conditions: Ulcerative Colitis
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Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through the Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast
NCT02993159
Recruiting
This randomized phase IIB trial studies how well tamoxifen or afimoxifene works in treating patients with estrogen receptor positive breast cancer. Estrogen can cause the growth of breast cancer cells. Hormone therapy using tamoxifen citrate or afimoxifene may fight breast cancer by blocking the use of estrogen by the tumor cells.
Gender:
Female
Ages:
18 years and above
Trial Updated:
12/17/2020
Locations: Northwestern University, Chicago, Illinois
Conditions: Ductal Breast Carcinoma In Situ, Estrogen Receptor Positive
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TXA in Spine Surgery
NCT04672213
Recruiting
As tranexamic acid (TXA) becomes more prevalent, all patients are receiving the same dose and method of delivery regardless of their pre-operative risk of transfusion. Therefore, the aim of the study is to determine whether or not repeated dosing of oral or a different method of delivery like intravenous (IV) TXA reduces the post-operative reduction in hemoglobin, hematocrit, number of transfusions, and postoperative blood loss following open spine surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/11/2020
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Postoperative Blood Loss Following Spine Surgery
Register for Updates
BoMI for Muscle Control
NCT04641793
Recruiting
People with spinal cord injury (SCI), stroke and other neurodegenerative disorders can follow two pathways for regaining independence and quality of life. One is through clinical interventions, including therapeutic exercises. The other is provided by assistive technologies, such as wheelchairs or robotic systems. In this study, we combine these two paths within a single framework by developing a new generation of body-machine interfaces (BoMI) supporting both assistive and rehabilitative goals.... Read More
Gender:
All
Ages:
Between 16 years and 65 years
Trial Updated:
11/17/2020
Locations: Shirley Ryan Ability Lab, Chicago, Illinois
Conditions: Spinal Cord Injury Cervical, Stroke
Register for Updates