Illinois is currently home to 2635 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Clinical Trial Evaluating the Efficacy, Safety, and Tolerability of Cariprazine in a Dose-Reduction Paradigm in the Prevention of Relapse in Patients With Schizophrenia
NCT04519099
Recruiting
To evaluate the efficacy and safety of cariprazine at a target dose of 4.5 mg/d compared with placebo in prevention of relapse in patients with schizophrenia To evaluate the efficacy and safety of cariprazine at a target dose of 3.0 mg/d compared with placebo in prevention of relapse in patients with schizophrenia who were initially stabilized on a target dose of 4.5 mg/d
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
08/17/2020
Locations: Alexian Brothers Hospital Network, Hoffman Estates, Illinois
Conditions: Schizophrenia
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Delirium Prevention Protocol in Elderly Patients
NCT03591120
Recruiting
The current study aims to elucidate the effectiveness of a preventative delirium protocol in patients older than 65 years of age undergoing elective surgery.
Gender:
All
Ages:
Between 65 years and 89 years
Trial Updated:
07/07/2020
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Delirium
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Convalescent Plasma as a Possible Treatment for COVID-19
NCT04442191
Recruiting
Patients who are ill with COVID-19 may benefit from receiving convalescent plasma infusions containing antibodies from donors who have recovered from the disease and are proven to no longer be infected. Given the current public health emergency due to COVID-19, the FDA has recently fast-tracked the use of convalescent plasma. The purpose for this study is to assess if convalescent plasma collected from donors previously infected with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
06/19/2020
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: COVID-19
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Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery
NCT03893734
Recruiting
A number of drugs used in the perioperative period may cause prolongation of the QT interval on the electrocardiogram (EKG). These drugs include inhalational agents, antiemetic agents, pain medications, and drugs used to reverse the effects of muscle relaxants. Approximately 80% of patients undergoing a general anesthetic will demonstrate significant prolongation of the QT interval on the EKG in the postanesthesia care unit (PACU) following surgery. The concern with QT interval prolongation is t... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
09/11/2019
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: EKG-QT Prolongation
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Safety and Efficacy Study of OMS721 in Patients With Atypical Hemolytic Uremic Syndrome
NCT03205995
Recruiting
The purpose of this study is to evaluate the platelet count change from baseline and safety of OMS721 in adults and adolescents with atypical hemolytic uremic syndrome (aHUS). The study will also evaluate pharmacokinetics (PK), pharmacodynamics (PD), and anti-drug antibody response (ADA).
Gender:
ALL
Ages:
12 years and above
Trial Updated:
10/17/2018
Locations: Omeros Investigational Site, Chicago, Illinois
Conditions: Thrombotic Microangiopathies, Atypical Hemolytic Uremic Syndrome
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Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
NCT02870244
Recruiting
Phase I clinical trial to determine the Phase II dose of autologous TIL 1383I TCR gene modified T Cells using a retrovirus. This is a novel National Cancer Institute (NCI) funded investigator initiated therapy for patients with advanced melanoma.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
03/08/2018
Locations: Loyola University Medical Center, Maywood, Illinois
Conditions: Melanoma
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Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis
NCT00004317
Recruiting
RATIONALE: Congenital toxoplasmosis is an infection caused by the parasitic organism Toxoplasma gondii, and it may be passed from an infected mother to her unborn child. The mother may have mild symptoms or no symptoms; the fetus, however, may experience damage to the eyes, nervous system, skin, and ears. The newborn may have a low birth weight, enlarged liver and spleen, jaundice, anemia, petechiae, and eye damage. Giving the antiparasitic drugs pyrimethamine and sulfadiazine is standard treatm... Read More
Gender:
ALL
Ages:
All
Trial Updated:
05/13/2009
Locations: University of Chicago, Chicago, Illinois
Conditions: Toxoplasmosis
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