Illinois is currently home to 2638 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Circadian Amplification in Diabetic Retinopathy
Recruiting
This study will test the effects of a 6-week comprehensive circadian optimization intervention Amplify-RHYTHM in patients with diabetic retinopathy. The outcomes of interest are objective and subjective sleep parameters, evening salivary cortisol and melatonin levels, and glucose parameters from continuous glucose monitoring
Gender:
ALL
Ages:
Between 40 years and 65 years
Trial Updated:
05/08/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Diabetic Retinopathy
Home Semen Testing in Men Beginning Attempts to Conceive
Recruiting
The overall objective of the proposed study is to enhance early detection of male factor infertility and reduce cost and morbidity associated with delayed diagnosis through development of a universal screening model based on home semen testing. The advent of inexpensive and accurate home semen testing has enabled a potential paradigm shift in the approach to male fertility evaluation. The investigator's central hypothesis is that universal home semen testing prior to attempts to conceive is easy... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: Northwestern University Department of Urology, Chicago, Illinois
Conditions: Male Infertility
A Health Action Process Approach Online Intervention for People With Multiple Sclerosis
Recruiting
The purpose of this study is to implement the person-centered internet-based Health Action Process Approach to promoting physical activity in people with Multiple Sclerosis (i.e., eHAPA-MS online intervention) and assess the intervention's effectiveness and adherence.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Multiple Sclerosis
An Individualized-health eLibrary App for People With Multiple Sclerosis
Recruiting
The purpose of this study is to assess the effectiveness after using a new individualized-health e-library app named SavvyHealth among people with multiple sclerosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Multiple Sclerosis
PARTNER 3 Trial - Aortic Valve-in-Valve
Recruiting
This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failing aortic bioprosthetic valve.
Gender:
ALL
Ages:
All
Trial Updated:
05/08/2024
Locations: Northwestern University Hospital, Chicago, Illinois
Conditions: Aortic Stenosis, Aortic Stenosis, Severe
Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans
Recruiting
This research study is being done to investigate if the GH Method exercise program positively affects body composition, improves physical abilities and can improve the overall sense of wellbeing (e.g. depression, PTSD, etc.) in U.S. Veterans. Subjects will be asked to complete 94 total visits (four (4) study testing visits and 90 exercise visits). Enrolled subjects will be tested for fitness, strength, and health risk factors at UIC 4 times and will complete 90 exercise training visits at the GH... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Chronic Pain, Acute Pain, Fatigue, Depression
Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss
Recruiting
The purpose of this study is to investigate the relationship between thigh strength and walking ability and assess if using a blood pressure cuff on the leg improves strength and walking performance.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: UIC Physical Therapy Faculty Practice, Chicago, Illinois
Conditions: Traumatic Amputation of Lower Extremity
Home-based FES Training in People With Chronic Stroke
Recruiting
This project will examine the feasibility, safety and effect of home-based functional electrical stimulation (FES) applied to different lower limb muscles in combination with task-specific training on gait, balance and mobility in adults with chronic stroke. 30 individuals with chronic stroke will first undergo initial screening and baseline walking, mobility, balance and strength assessments in the laboratory. After determining their eligibility for the study, they will undergo 12-weeks of home... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
05/06/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Chronic Stroke
Physical Activity Intervention for Black Women With Asthma
Recruiting
Physical inactivity is associated with poor asthma control and quality of life, and greater health care utilization. Rates of physical inactivity, asthma, and asthma mortality among Black women are higher than those of their White counterparts. Our formative work identified barriers to PA among Black women with asthma including a lack of social support, self-efficacy, unsafe neighborhood and fear related to experiences with life-threatening asthma exacerbations. Given the unique barriers to PA a... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Asthma
Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)
Recruiting
In this project, the proposition is that the use of daily dosed Myfembree ( a combination of relugolix with estradiol and norethindrone acetate), FDA-approved medication to treat heavy menses fibroid-related symptoms, has the potential to delay the recurrence of fibroid symptoms, prolong the improved quality of life and delay the need for re-intervention after uterine sparing surgery versus the routine standard of care.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Chicago South Loop, Chicago, Illinois
Conditions: Metrorrhagia, Pelvic Pain, Menorrhagia, Leiomyoma
Levonorgestrel 52 mg IUD for Emergency Contraception and Same-Day Start
Recruiting
This is a prospective clinical research study to test the effectiveness of the Levonorgestrel (LNG) 52 mg Intrauterine Device (IUD) for emergency contraception (EC) and same-day start use that will enroll people receiving care at Planned Parenthood affiliates across the U.S. Our prior work demonstrated efficacy (shows that it works in an ideal setting) for the LNG 52 mg IUD for these uses and this study will test effectiveness (how well it works in the real world) in a larger, heterogenous popul... Read More
Gender:
FEMALE
Ages:
Between 16 years and 35 years
Trial Updated:
05/06/2024
Locations: Planned Parenthood Illinoi, Chicago, Illinois
Conditions: Contraception
Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers
Recruiting
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data on 2 commercially available SOC treatments for Diabetic Foot Wounds.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: Gateway Clinical Trials, O'Fallon, Illinois
Conditions: Diabetic Foot Ulcer, Ulcer Foot, Diabetic Foot