Illinois is currently home to 2669 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Umbrella Study for Analysis of Data Related to Patients With Cancer
NCT06018753
Recruiting
This study is a multisite, minimal risk, non-interventional study using patient electronic health record data collected as part of standard of care to answer cohort-based research questions and create robust real-world data sets.
Gender:
ALL
Ages:
All
Trial Updated:
04/09/2025
Locations: Illinois Cancer Care, Peoria, Illinois
Conditions: Cancer
Register for Updates
SEAL™IT: Saccular Endovascular Aneurysm Lattice System Interventional Pivotal Trial
NCT05831202
Recruiting
To establish the safety and effectiveness of the SEAL™ Saccular Endovascular Aneurysm Lattice system for the treatment of saccular intracranial aneurysms. The data from this study will be used to support a premarket approval (PMA) submission.
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
04/09/2025
Locations: Endeavor Health - Northwest Community Hospital, Arlington Heights, Illinois
Conditions: Intracranial Aneurysm
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A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder
NCT05729373
Recruiting
A clinical study that will meaure how well SEP-363856 works and how safe it is in adults with Generalized Anixety Disorder. This study will be accepting both male and female subjects between the ages of 18 years and 65 years old. The study will be held in Approximately 50 global study centers and approximately 15 additional centers for a separate Japan population. Participation in the study can be up to approximately 12 weeks.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/09/2025
Locations: Uptown Research Institute, LLC, Chicago, Illinois
Conditions: Generalized Anxiety Disorder
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FXR Effect on Severe Alcohol-Associated Hepatitis (FRESH) Study
NCT05639543
Recruiting
The purpose of this trial is to assess dose related safety, efficacy, and pharmacokinetics (PK) of INT-787 in participants with severe alcohol-associated hepatitis (sAH).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/09/2025
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Alcohol Associated Hepatitis
Register for Updates
Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
NCT00198068
Recruiting
The PROMISSE Study is an observational study of 700 pregnant patients, enrolled at nine major clinical centers. The purpose of the study is 1) to determine whether certain proteins (called complement split products) that can injure healthy organs can be used to predict poor pregnancy outcome in patients with systemic lupus erythematosus (SLE) and anti-phospholipid syndrome (APS), and/or 2) to determine whether elevated levels of circulating antiangiogenic factors predict pregnancy complications... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
04/09/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Systemic Lupus Erythematosus, Antiphospholipid Syndrome
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Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD
NCT05566769
Recruiting
NMOSDCopilot is a digital tool developed for the self-assessment of Neuromyelitis Optica Spectrum Disorder symptoms that impact patients' functioning and quality of life. It has been co-designed with the help of patient advocacy groups, NMOSD patients and medical experts. It includes a smartphone-based application for patients, connected to a web portal developed for healthcare professionals (HCSPs). The patient application is composed of vision, walking, cognition, and dexterity e-active tests... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/08/2025
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: Neuromyelitis Optica
Register for Updates
Study to Evaluate the Efficacy of a Probiotic in Infantile Colic Symptoms Relief
NCT05432479
Recruiting
This study evaluates the efficacy of single strain probiotic administered in a form of a sachet in the treatment of infant colic in infants 3-12 weeks old.
Gender:
ALL
Ages:
Between 3 weeks and 12 weeks
Trial Updated:
04/08/2025
Locations: Atlantia Food Clinical Trials, Chicago, Illinois
Conditions: Infantile Colic
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Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis
NCT05427695
Recruiting
The purpose of this randomized study will be to determine whether topical probiotic sinus irrigations are more effective compared to saline sinus irrigation controls in the treatment of active CRS in patients who have had prior sinus surgery based on subjective and objective outcome measures.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/08/2025
Locations: University of Illinois Hospitals & Health Sciences System, Chicago, Illinois
Conditions: Chronic Rhinosinusitis (Diagnosis)
Register for Updates
Pulmonary Fibrosis Foundation Community Registry
NCT05382572
Recruiting
Pulmonary fibrosis (PF) results from a diverse group of health conditions and affects the lives of patients (including those who are post lung transplant), caregivers and family members. The Pulmonary Fibrosis Foundation Community Registry will offer an online portal where participants can self-enroll and directly contribute information about their experience with PF to be compiled into a longitudinal data set for use by researchers.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/08/2025
Locations: Pulmonary Fibrosis Foundation, Chicago, Illinois
Conditions: Pulmonary Fibrosis, Interstitial Lung Disease, Lung Fibrosis, Idiopathic Pulmonary Fibrosis
Register for Updates
Comprehensive Care Community and Culture Study
NCT04489693
Recruiting
This randomized trial is evaluating whether socioeconomically disadvantaged Medicare patients at increased risk of hospitalization experience fewer hospitalization if those patients are offered care in: 1) ACCT, where patients receive care from different physicians in the hospital and the clinic settings and have access to nurse and social worker care coordination services, 2) CCP where patients receive care from one physician in the inpatient and outpatient settings or 3) C4P which adds screeni... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/08/2025
Locations: David Meltzer, Chicago, Illinois
Conditions: Comprehensive Care, Quality of Care, Medicare, Cost of Care
Register for Updates
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
NCT04124120
Recruiting
The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grfating (SAG). The specific aims of ROMA:Women are: Aim 1: Determine the impact of MAG vs SAG on major adverse cardiac and cerebrovascular events in women undergoing coronary artery bypass grfating (CABG). The investigators will compare major adverse cardiac and cerebrovascular events (death, stroke, non-procedural myocar... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/04/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
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A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects With PAF:
NCT06676072
Recruiting
The objective of this clinical study is to demonstrate that ablation with the TactiFlex SE Ablation catheter, in conjunction with a compatible pulsed field ablation (PFA) and/or radio frequency (RF) generator, is safe and effective for the treatment of symptomatic, recurrent, drug refractory paroxysmal atrial fibrillation (PAF).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2025
Locations: Loyola University Medical Center, Maywood, Illinois
Conditions: Atrial Fibrillation (AF), Atrial Arrhythmia, Paroxysmal AF, Drug Refractory Paroxysmal Atrial Fibrillation
Register for Updates