Illinois is currently home to 2679 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)
Recruiting
The over-arching research question is: Does message (Advise) and referral approach (Refer) influence a patient's willingness to "opt-in" to receive a call from an Illinois Tobacco Quitline (ITQL) smoking cessation coach in patients at MSHC. Primary UH3 study aim: Compare the effect of the portal-delivered Choice message (Arm 1) to the Information-only message (Arm 3) on linkage to the Illinois Tobacco Quitline (i.e., spoke to a Quitline coach). Secondary UH3 aims are to: Examine the reach of... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/04/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Tobacco Use Cessation
Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration
Recruiting
Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (axitinib implant) in Subjects with Neovascular Age-Related Macular Degeneration
Gender:
ALL
Ages:
50 years and above
Trial Updated:
07/03/2024
Locations: Illinois Retina Associates, S.C. - Lincoln Park, Chicago, Illinois
Conditions: Neovascular Age-Related Macular Degeneration
MRI Screening in Men at High Risk of Developing Prostate Cancer
Recruiting
The purpose of this study is to determine whether or not Magnetic Resonance Images (MRI) will identify high-grade cancers earlier and more frequently in men at high risk of developing prostate cancer.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/03/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Prostate Cancer Screening
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment
Recruiting
The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to study the correlation of having a 3D printed model with improvement in patient outcomes and compare those with patients who have had a VAD placement without a 3D model.
Gender:
ALL
Ages:
All
Trial Updated:
07/03/2024
Locations: Lurie Children's Hospital, Chicago, Illinois
Conditions: Congenital Heart Disease
Pilot Study of Acute Stroke Using the Brainpulse™
Recruiting
The aim of this pilot study is to collect data on stroke patients using the BrainPulse Stroke Monitor. Patient characteristics, diagnostic procedures and clinical outcomes will be documented as part of the data collected to assess the clinical utility of the BrainPulse device. All eligible patients will be enrolled and assigned to a study Group based on confirmation of their diagnosis: Acute Ischemic Stroke, Hemorrhagic Stroke, Transient Ischemic Attack or No Stroke. The data collected from the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2024
Locations: NorthShore University Health System, Evanston, Illinois
Conditions: Stroke, Acute
Liposomal Bupivacaine Use in Alveolar Bone Graft Patients
Recruiting
The goal of this clinical trial is to learn if a pain medication called liposomal bupivacaine (brand name EXPAREL®) with epinephrine will provide better pain control, increased activity, and reduced use of opioids compared with the standard treatment for patients age 6 years and older with cleft lip and palate who have had an alveolar bone graft surgery. Investigators will look at: * pain scores at hip and jaw sites * opioid use in amount and frequency * scores on activity questionnaires Resear... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
07/02/2024
Locations: Shriners Children's Chicago, Chicago, Illinois
Conditions: Cleft Lip and Palate
Training Swallowing Initiation During Expiration
Recruiting
Head and neck cancers have escalated to epidemic levels in the United States, and survivors are suffering from life-long, devastating swallowing disorders with limited therapeutic options. This clinical trial investigates a novel swallowing treatment that trains initiation of swallowing during the expiratory phase of respiration to improve swallowing safety and efficiency.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/02/2024
Locations: Northwestern Memorial Hospital, Chicago, Illinois
Conditions: Head and Neck Cancer, Dysphagia, Oropharyngeal Dysphagia, Oropharynx Squamous Cell Carcinoma
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
Recruiting
This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.
Gender:
ALL
Ages:
Between 50 years and 70 years
Trial Updated:
07/02/2024
Locations: Rush - Copley Medical Center, Aurora, Illinois
Conditions: Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum
A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer
Recruiting
This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune checkpoint therapy with atezolizumab in participant with recurrent and/or persistent endometrial cancer. The main protocol provides a platform for genomic screening with homogeneous basic eligibility criteria in order to direct study participants into biomarker-matched study cohorts consisting of testing targeted agents.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/02/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Endometrial Cancer
Personal BP - CAI Study
Recruiting
A single-center, prospective, observational pilot of the Cerebral Adaptive Index for assessing personalized blood pressure targets
Gender:
ALL
Ages:
45 years and above
Trial Updated:
07/01/2024
Locations: Northwestern University Hospital, Evanston, Illinois
Conditions: Blood Pressure
Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off
Recruiting
The purpose of this study is to compare Moses 2.0 pulse modulation technology and the standard high powered Holmium Laser lithotripsy and how it will affect time in the operating room, time using the laser, laser energy, and stone free rates. Currently Moses 2.0 laser technology is FDA approved and currently used in practice since 2021. No study to this date has compared Moses 2.0 without pulse modulation laser technology to Moses 2.0 with pulse modulation laser technology. The study will be i... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
07/01/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Kidney Stone, Ureteral Stone
Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms
Recruiting
The objective of our multi-center randomized single-blind study is to examine the safety and effect of intra-detrusor OnabotulinumtoxinA injections at the time of holium laser enucleation of the prostate (HoLEP) in men with overactive bladder symptoms with and without urge incontinence.
Gender:
MALE
Ages:
Between 18 years and 89 years
Trial Updated:
07/01/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Urinary Incontinence, Overactive Bladder Syndrome, Overactive Bladder, Urologic Diseases