Illinois is currently home to 2634 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The PIVOT Trial: Project on EHR-Integrated Lifestyle Interventions for Adults Aged Fifty and Older
NCT05654142
Recruiting
This is a multisite clinical trial of healthy lifestyle programs for middle-to-older-aged adults (50 -74 years) to improve their weight and, therefore, reduce risk for chronic disease. This study will investigate whether a proven, self-directed video-based lifestyle program can be significantly enhanced with the assistance of a coach via videoconference or phone to help people as they adopt healthy eating and exercise behaviors. Additionally, the study will examine what factors might explain why... Read More
Gender:
ALL
Ages:
Between 50 years and 74 years
Trial Updated:
12/05/2024
Locations: Department of Medicine, Vitoux Program on Aging and Prevention, Chicago, Illinois
Conditions: CARDIOMETABOLIC CONDITIONS, Obesity, Pre-diabetes, Metabolic Syndrome, Type2diabetes, Hypertension, Dyslipidemias
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Stroke Thrombectomy and Aneurysm Registry
NCT04994756
Recruiting
This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the brain, an abnormal ballooning of an artery, abnormal tangling of blood vessels, abnormal formation of blood vessels, tearing of vein, and bleeding in the brain. This information is used to help predict outcomes that undergo an operation for treatment of the above-listed brai... Read More
Gender:
ALL
Ages:
Between 1 year and 120 years
Trial Updated:
12/05/2024
Locations: Rush University, Chicago, Illinois
Conditions: Stroke, Thromboses, Intracranial, Aneurysm, Brain
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Post-Market Study to Assess iTind Safety in Comparison to UroLift
NCT04757116
Recruiting
The study objective is to evaluate the safety of the iTind device comparied to UroLift.
Gender:
MALE
Ages:
50 years and above
Trial Updated:
12/05/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Benign Prostatic Hyperplasia (BPH)
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Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors
NCT03803423
Recruiting
This study utilizes a web-based application to help patients on the organ transplant waitlist communicate patient's need for a living donor via social media and provide interested potential donors the opportunity to engage with the evaluation process.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: End Stage Renal Disease, End Stage Liver Disease
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Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma
NCT02847559
Recruiting
The purpose of this research study is to determine the effects bevacizumab (the study drug) combined with Optune (the study device) tumor treatment field therapy has on meningiomas. Bevacizumab is considered investigational because the US Food and Drug Administration (FDA) has not approved its use for the treatment of meningiomas. The study drug is a medication that blocks the growth of new blood vessels. It is thought that the study drug may interfere with the growth of new blood vessels and th... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Anaplastic (Malignant) Meningioma, Atypical Meningioma, Grade II Meningioma, Grade III Meningioma, Recurrent Meningioma, Supratentorial Meningioma
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Beyond MARS: Magnetic Resonance Study: A Novel Assessment of Placental Perfusion During Pregnancy
NCT06314009
Recruiting
The purpose of this study is to evaluate the flow of oxygen and blood necessary for nutrient transfer across the placenta during the second and third trimesters in pregnancy in women who are obese before pregnancy compared to women who have an average weight before pregnancy. This study will evaluate blood flow across the placenta by functional Magnetic Resonance Imaging (fMRI) using arterial spin labeling (ASL). The investigators hypothesize that there will be differences in placental oxygenati... Read More
Gender:
FEMALE
Ages:
Between 18 years and 60 years
Trial Updated:
12/04/2024
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: Placenta Diseases
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Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
NCT05476770
Recruiting
Tagraxofusp is a protein-drug conjugate consisting of a diphtheria toxin redirected to target CD123 has been approved for treatment in pediatric and adult patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN). This trial aims to examine the safety of this novel agent in pediatric patients with relapsed/refractory hematologic malignancies. The mechanism by which tagraxofusp kills cells is distinct from that of conventional chemotherapy. Tagraxofusp directly targets CD123 that is pre... Read More
Gender:
ALL
Ages:
Between 1 year and 21 years
Trial Updated:
12/04/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Hematologic Malignancy, AML, ALL, BPDCN, MDS, Lymphoblastic Lymphoma, Lymphoma, B-Cell, Lymphoma, T-Cell, Hodgkin Lymphoma, Mixed Phenotype Acute Leukemia, Acute Undifferentiated Leukemia
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REMASTer: REcurrent Brain Metastases After SRS Trial
NCT05124912
Recruiting
Randomized, post-market multi-center study investigating the efficacy of two sets of treatment algorithms in brain metastases (BM) patients at the time of first intervention for radiographic progression after stereotactic radiosurgery (SRS), with or without surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Brain Metastases, Radiation Necrosis, Recurrent Tumor, Recurrent Metastases
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Vasoactive Drugs in Intensive Care Unit
NCT02118467
Recruiting
The investigators hypothesis is that for ICU patients with shock, the use of the vasoactive drugs phenylephrine and vasopressin will reduce tachydysrhythmias when compared to norepinephrine and epinephrine. To investigate this hypothesis, the investigators are conducting a randomized double blind controlled trial comparing phenylephrine and vasopressin vs. norepinephrine and epinephrine in ICU patients with shock that is not responsive to IV fluids. All patients admitted to the adult intensive c... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/04/2024
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Shock
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Effects of Vibration on Motor Function of Survivors of Chronic Stroke
NCT06663501
Recruiting
The aim of this study is to evaluate how vibration of the tendons enhances arm and hand training in survivors of chronic stroke. The investigators hypothesize that wrist/elbow robotic training, combined with body awareness training will improve arm and hand function in individuals with chronic stroke.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
12/03/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Stroke, Healthy
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CCHS Secure Health-hub Advancing Research Efforts (CCHS SHARE)
NCT06554275
Recruiting
The purpose of this study is to capture longitudinal natural history data in Congenital Central Hypoventilation Syndrome (CCHS). This will include capturing standardized clinical data from standard of care assessments at several CCHS referral centers. Funding source-FDA OOPD
Gender:
ALL
Ages:
All
Trial Updated:
12/03/2024
Locations: Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Congenital Central Hypoventilation Syndrome
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Nutrition for Precision Health, Powered by the All of Us
NCT05701657
Recruiting
The goal of this investigational study is to develop algorithms that predict human response to foods. The main question it aims to answer are: * How does varying foods and eating patterns impact one's biological and physiological responses? * In what ways can novel dietary assessment measures be used to improve dietary assessments and to prescribe assessments to people in future research with increased precision? * Can artificial intelligence and machine learning techniques be combined to presc... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Nutrition, Health, Dietary Habits
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