Illinois is currently home to 2634 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Enhancing Immune Health Randomized Controlled Trial
NCT05639881
Recruiting
This study tests a psychosocial intervention to improve immune health literacy and behaviors among adults with mental illnesses.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Mental Disorder
Register for Updates
Antidepressant Effects of Nitrous Oxide
NCT05357040
Recruiting
To evaluate the acute and sustained antidepressant effects of nitrous oxide in people with major depressive disorder; and further evaluate these effects by identifying the optimal dose and regimen to guide current practice, and to plan a future large pragmatic trial.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Chicago Medicine, Chicago, Illinois
Conditions: Major Depressive Disorder, Treatment Resistant Depression
Register for Updates
Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
NCT05336890
Recruiting
Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Early detection and intervention are critical to mitigate the impact of these impairments. Mechanisms leading from premature birth to these undesirable outcomes remain unclear, and accurate prognostic me... Read More
Gender:
ALL
Ages:
Between 30 weeks and 83 months
Trial Updated:
12/03/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Premature Birth, Asthma in Children, Sleep-Disordered Breathing, Neurodevelopmental Disorders
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Oral Statins and Protection From Hearing Loss
NCT04826237
Recruiting
A small clinical trial for idiopathic sudden sensorineural hearing loss (ISSNHL). Will the addition of an oral statin to the standard treatment (oral methylprednesolone and the salvage therapy of intratympanic dexamethasone) improve the treatment outcome for patients with ISSNHL? This study will compare the two treatments and quantitatively evaluate hearing and speech discrimination and have the patients subjectively evaluate tinnitus.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/03/2024
Locations: Northwestern Memorial Hospital, Chicago, Illinois
Conditions: Sudden Sensorineural Hearing Loss
Register for Updates
Optimizing Tobacco Use Treatment for PLWHA
NCT04176172
Recruiting
The advent of anti-retroviral therapy (ART) for people living with HIV/AIDS (PLWHA) substantially improved life expectancy but has also led to the critical need to address modifiable risk factors associated with cancer and cardiovascular disease, such as tobacco smoking. HIV-infected smokers lose more life-years due to tobacco use than they do to their HIV infection. There have been relatively few studies of tobacco use treatments for PLWHA and systematic reviews show that there are insufficien... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: HIV/AIDS, Nicotine Dependence
Register for Updates
Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
NCT06719583
Recruiting
BLAAC PD is a research study to understand what Parkinson's disease looks like for Black and African American communities. BLAAC PD is happening at research centers around the United States. The study is part of the Global Parkinson's Genetics Program (GP2). GP2 is a research project working to transform understanding of the genetics of Parkinson's disease and make that knowledge globally relevant.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2024
Locations: Rush University, Chicago, Illinois
Conditions: Parkinson Disease
Register for Updates
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients
NCT06690398
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients aged 5 to 17 years with a primary diagnosis of irritability associated with Autism Spectrum Disorder (ASD) based on Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition Text Revision (DSM-5-TR) and confirmed by the Kiddie Schedule for Affective Disorders and Schizophrenia Present and Lifetime Version (K-SADS-PL).
Gender:
ALL
Ages:
Between 5 years and 17 years
Trial Updated:
12/02/2024
Locations: Clinical Site, Arlington Heights, Illinois
Conditions: Irritability Associated With Autism Spectrum Disorder
Register for Updates
Hyrax Vs. Invisalign Palatal Expander Clinical Study
NCT06662279
Recruiting
The purpose of this study is to compare expansion result and the overall experience between the Invisalign Palatal Expander and the Hyrax expander.
Gender:
ALL
Ages:
Between 6 years and 11 years
Trial Updated:
12/02/2024
Locations: Innovative Orthodontic Centers, Naperville, Illinois
Conditions: Malocclusions, Narrow Maxilla, Narrow Maxillary Arch, Crowding
Register for Updates
Executive Function and Parenting in Childhood
NCT06241300
Recruiting
Deficits in executive functioning (EF) disproportionately impact children living in poverty and increase risk for psychopathology, particularly disruptive behavior disorders. This randomized clinical trial seeks to determine whether childhood EF, assessed across neural and behavioral units of analysis, is an experimental therapeutic target that can be directly modified through caregiver participation in the Chicago Parent Program (CPP), if increases in EF predict reduced disruptive behavior traj... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
12/02/2024
Locations: University of Illinois-Chicago, Chicago, Illinois
Conditions: Disruptive Behavior Disorder, Childhood Onset, Disruptive Behavior, Executive Function
Register for Updates
Study of Vudalimab or Pembrolizumab in Combination With Chemotherapy as First-line Treatment in Patients With Advanced NSCLC
NCT06173505
Recruiting
The purpose of this study is to identify the recommended dose of vudalimab to be used in combination with chemotherapy (Part 1) and to evaluate the efficacy and safety of vudalimab plus standard of care chemotherapy relative to pembrolizumab plus chemotherapy (Part 2) as first-line treatment in patients with nonsquamous non-small cell lung cancer (NSCLC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/02/2024
Locations: Midwestern Regional Medical Center, Zion, Illinois
Conditions: Nonsquamous Non-small Cell Lung Cancer
Register for Updates
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
NCT05611242
Recruiting
The primary objective is to establish the efficacy of intra-arterial (IA) mechanical thrombectomy (MT) with extracranial proximal carotid artery acute stenting versus non-stenting approaches in patients with acute ischemic stroke (AIS) from intracranial vessel occlusion (IVO) in the anterior circulation and have a proximal carotid occlusive disease (occlusion or severe stenosis).
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
12/02/2024
Locations: Ascension/Alexian Brothers Health System, Chicago, Illinois
Conditions: Acute Ischemic Stroke
Register for Updates
C-STAR Movement Database
NCT05471375
Recruiting
The purpose of this study is to develop a database that contains movement and rehabilitation-related data collected through the use of wearable sensors and video. This database will serve as a resource for clinicians and researchers interested in the investigation of movement or rehabilitation-related research ideas.
Gender:
ALL
Ages:
99 years and below
Trial Updated:
12/02/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Stroke, Parkinson Disease, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
Register for Updates