Illinois is currently home to 2668 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Genetic Factors in Chronic Sinusitis
Recruiting
The purpose of this study is to learn more about the genetics of chronic sinusitis and identify genes involved in chronic sinusitis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Chronic Sinusitis
Investigation of the Effects of a Bifidobacterial Strain on Bowel Movement in Healthy Adults
Recruiting
The goal of this clinical trial is to investigate whether a supplement containing the B. longum strain works to alleviate constipation in adults. The main questions it aims to answer are: Does a supplement containing the B. longum strain increase the number of spontaneous bowel movements per week, improve stool consistency, and enhance the quality of life? Participants will: Take a supplement containing the B. longum strain or a placebo every day for 8 weeks. Maintain an e-diary as per the... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/31/2025
Locations: Atlantia Clinical Trials, Chicago, Illinois
Conditions: Infrequent Bowel Movements
Goal Attainment and Physical Activity in People With Hemophilia A
Recruiting
This is a Phase 4, multi-center, observational study conducted in patients aged 12 to 50 years with moderate or severe hemophilia A who are newly starting prophylaxis with efa in the US and Japan. This study aims to enroll 35 patients.
Gender:
ALL
Ages:
Between 12 years and 50 years
Trial Updated:
01/31/2025
Locations: Bleeding and Clotting Disorders Institute, Peoria, Illinois
Conditions: Hemophilia A
VOICE-Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study
Recruiting
The primary aim of this study is to explore the time course of response to Vedolizumab in participants with CD as measured by the Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference-short form (SF), as well as other PROMIS domain SFs (fatigue, anxiety, depression, sleep disturbance, physical function, and ability to participate in social roles and activities); other PRO measures will also be assessed.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: Northwestern University, Evanston, Illinois
Conditions: Crohn's Disease
Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients with Chronic Spontaneous Urticaria (CSU)
Recruiting
This trial will be performed as a three-part dose escalating clinical trial where Parts 1 is open label and Parts 2 and 3 are randomized, double-blinded, and placebo-controlled. The trial is intended to determine the safety and tolerability and assess the preliminary efficacy of briquilimab in adult participants with chronic spontaneous urticaria (CSU), who remain symptomatic despite treatment with H1 antihistamines and omalizumab. Additionally, pharmacokinetic (PK) properties of briquilimab, a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: Site 124, Springfield, Illinois
Conditions: Chronic Spontaneous Urticaria
MyPEEPS LITE Trial
Recruiting
This study will use community-informed advertisements and messages through electronic methods to recruit and retain a large (N=2,500), diverse national sample of high-risk young men who have sex with men (YMSM) and non-binary individuals that are assigned male sex at birth, 16-29 years of age to determine the efficacy of the MyPEEPS Mobile intervention on reduced incident HIV infections in comparison to a standard of care condition and to examine the degree to which reduced incident HIV infectio... Read More
Gender:
MALE
Ages:
Between 16 years and 29 years
Trial Updated:
01/30/2025
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: HIV/AIDS
bpMedManage: Digital Technology to Support Adherence to Hypertension Medications
Recruiting
The purpose of the bpMedManage study is to rigorously test the efficacy of a smartphone technology to help improve high blood pressure medication adherence among older adults with mild cognitive impairment (MCI) in a 16-week randomized controlled trial. A total of 100 older adults will be recruited. There will be two treatment arms, bpMedManage-S and bpMedManage-P with 50 participants in each arm. Participants randomized into the bpMEDManage-S intervention arm will use a smartphone application w... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
01/30/2025
Locations: University of Illinois, Urbana-Champaign, Champaign, Illinois
Conditions: Aging, Mild Cognitive Impairment, Hypertension
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
Recruiting
This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. After confirmation of eligibility criteria, patients will be randomized to either the standard arm or experimental arm.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/30/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
Observational Study of Ostomy Consumers
Recruiting
The purpose of this longitudinal prospective observational study is to collect electronic Patient Reported Outcome (ePRO) data over a 7-year period directly from people living with an ostomy and their caregivers (participants were re-consented with version 3 of the Protocol in 2020 which indicated a study duration of 5 years, and version 6 of the Protocol in 2025 extending for an additional 2 years). Research participants will be asked to self-report on the ostomy pouching systems they typically... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/30/2025
Locations: Hollister Incorporated, Libertyville, Illinois
Conditions: Ostomy
AlloMend Acellular Dermal Matrix Allograft in Pre-Pectoral Breast Reconstruction
Recruiting
This is a single-center, retrospective study which will be used to describe and evaluate the effectiveness of AlloMend® Acellular Dermal Matrix allograft for patients that have undergone Pre-Pectoral Breast Reconstruction surgery following a single or double mastectomy.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Alan H. Chen Surgical Associates, PC, Joliet, Illinois
Conditions: Pre-Pectoral Breast Reconstruction Following Single or Double Mastectomy
Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients
Recruiting
The purpose of this study is to analyze Fitbit data to predict infection after surgery for complicated appendicitis and the effect this prediction has on clinician decision making.
Gender:
ALL
Ages:
Between 3 years and 18 years
Trial Updated:
01/29/2025
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Appendectomy, Appendicitis, Appendicitis Acute
Web Intervention for Parents of Youth With Genetic Syndromes (WINGS)
Recruiting
The purpose of this study is to evaluate the effectiveness of an adapted, telehealth functional behavioral therapy (FBTsIDD) specifically focused on promoting appropriate communication and behavioral strategies in individuals with syndromic intellectual and developmental disorders. Participants will be asked to complete virtual study assessments at intake and then on a monthly basis for the duration of 3-6 months. In addition, participants will attend weekly or biweekly virtual intervention vis... Read More
Gender:
ALL
Ages:
Between 2 years and 12 years
Trial Updated:
01/29/2025
Locations: Autism Assessment Research Treatment and Services (AARTS) Center at Rush University Medical Center, Chicago, Illinois
Conditions: Telomeric 22Q13 Monosomy Syndrome, Tuberous Sclerosis, Hamartoma Syndrome, Multiple, Fragile X Syndrome, Angelman Syndrome, Rett Syndrome, Chromosome 15Q, Partial Deletion, Creatine Deficiency, X-linked