Illinois is currently home to 2672 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Church-based Intervention to Improve Blood Pressure in African Americans
NCT05220332
Recruiting
This is a 12-month behavioral cluster-randomized trial testing a church-based intervention to reduce blood pressure in African Americans with uncontrolled blood pressure.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Hypertension
Register for Updates
Comparison of Partial Rotator Cuff Repair vs. Superior Capsular Reconstruction for Irreparable Rotator Cuff Tears
NCT04742452
Recruiting
The primary objective of this prospective randomized controlled trial is to compare pain and functional outcomes between two surgical modalities for irreparable rotator cuff tears as measured by the pain visual analog scale (VAS), simple shoulder test (SST), American Shoulder and Elbow Surgery shoulder score (ASES), and Patient Reported Outcomes Measurement Information System (PROMIS) 29 score at 6 weeks, 3, 6, 12, and 24 months post-operatively. The two surgical modalities of interest are parti... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
01/14/2025
Locations: Midwest Orthopaedics at Rush, Chicago, Illinois
Conditions: Rotator Cuff Tears
Register for Updates
GORE® ENFORM Biomaterial Product Study
NCT04718168
Recruiting
A prospective, retrospective, non-randomized, multicenter study with two independent hernia study cohorts (Ventral / Incisional Hernia Repair and Diaphragmatic / Hiatal Hernia Repair). The primary objective of this study is to collect GORE® ENFORM Biomaterial product commercial-use data on device functional performance and short-term patient experience.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Northshore University Health System Research Institute, Evanston, Illinois
Conditions: Hernia, Hiatal, Hernia, Diaphragmatic, Hernia, Ventral, Incisional Hernia
Register for Updates
Von Willebrand Factor in Pregnancy (VIP) Study
NCT04146376
Recruiting
In pregnant women with von Willebrand disease (VWD) who by the third trimester do not have von Willebrand factor (VWF) or factor VIII (FVIII) levels greater than 50-100%, specific guidance is lacking for delivery planning in terms of how high of a VWF level should be achieved to reduce bleeding. This is a prospective, open-label, cohort study in women with VWD using Wilate VWF replacement therapy to maintain trough or minimum VWF levels of 100-150% for delivery and the immediate postpartum peri... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Bleeding & Clotting Disorders Institute, Peoria, Illinois
Conditions: Von Willebrand Diseases
Register for Updates
Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
NCT06639503
Recruiting
The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the participant surgical incision. The investigators hope to discover if providing numbing medication to a nerve that controls pain in a larger area of the knee (a nerve block), might be better at post-operative pain control.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Tibial Plateau Fractures
Register for Updates
Lynch Syndrome Integrative Epidemiology and Genetics
NCT06582914
Recruiting
The vision of the "Lynch syndrome INtegrative Epidemiology And GEnetics" (LINEAGE) Consortium is to collaboratively improve the lives and longevity of individuals and families with Lynch syndrome. The mission of the LINEAGE Consortium is to collaboratively improve Lynch syndrome care through high-quality research. This consortium will provide intellectual and infrastructure support to facilitate development of research questions, collection of standardized data and biospecimens, support of gran... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Lynch Syndrome
Register for Updates
Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
NCT05783245
Recruiting
This study seeks to perform an appropriately-powered study to evaluate any clinical difference between continuous cooling therapy and traditional ice for treatment of post-operative pain in open CTR surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: University of Chicago Medicine, Chicago, Illinois
Conditions: Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Register for Updates
Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer
NCT04918186
Recruiting
This study is being done to answer the following question: What are the effects of a new drug or drugs on ovarian cancer? The pre-study screening may be done to test a sample of tissue for biomarkers to determine participation in the study.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: The University of Chicago Medical Center, Chicago, Illinois
Conditions: Ovarian Cancer
Register for Updates
NBTXR3 Activated by Radiotherapy for Patients with Advanced Cancers Treated with an Anti-PD-1 Therapy
NCT03589339
Recruiting
The 1100 study is an open-label, Phase I, dose escalation and expansion prospective clinical study to assess the safety of intratumoral injection of NBTXR3 activated by radiotherapy in combination with anti-PD-1 therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Radiotherapy, Immunotherapy, Microsatellite Instability-High Solid Malignant Tumour, Squamous Cell Carcinoma of Head and Neck, Metastasis From Malignant Tumor of Cervix, Metastasis From Malignant Melanoma of Skin (Disorder), Metastasis From Malignant Tumor of Bladder (Disorder), Metastasis From Malignant Tumor of Liver, Metastatic Renal Cell Carcinoma, Metastatic Triple-Negative Breast Carcinoma, Metastatic NSCLC
Register for Updates
Objective Assessment of Outcomes Following Immediate Lymphatic Reconstruction / LYMPHA
NCT06650592
Recruiting
Immediate lymphatic reconstruction (ILR) is a novel surgical approach performed at the time of initial lymph node dissection with the goal of preventing lymphedema. It involves the identification of lymphatic channels that are transected after lymph node dissection and microsurgical anastomosis of one or more lymphatic channel with a local recipient vein to re-direct upper extremity lymphatic drainage. Although ILR carries significant promise in prevention of lymphedema, there is a lack of high-... Read More
Gender:
ALL
Ages:
All
Trial Updated:
01/10/2025
Locations: The University o Chicago, Chicago, Illinois
Conditions: Lymphatic Reconstruction
Register for Updates
Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain
NCT06635889
Recruiting
Post-operative pain and lower urinary tract symptoms are common following ureteroscopy in the treatment of stone disease. The use of bupivacaine as a topical pain medication is used routinely for other urologic procedures, however, to date there are no studies that have rigorously investigated the effect of instilling bupivacaine in the bladder following ureteroscopy. This is a randomized study that will investigate the effect of instilling bupivacaine in the bladder following routine ureterosc... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/10/2025
Locations: The University of Chicago Medical Center, Chicago, Illinois
Conditions: Nephrolithiasis
Register for Updates
Perinatal Transmission of MDR Bacteria
NCT06148480
Recruiting
The investigators aim to conduct a prospective surveillance study of mothers and their infants born vaginally or by scheduled C-section and who are admitted to Northwestern Medicine Prentice Women's Hospital to determine the prevalence of ESBL-E carriage in healthy post-partum women and the transmission rate of these strains to their infants. Using whole genome sequencing and a comparative genomics approach the investigators will determine the relatedness of strains among mother-infant dyads as... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
01/10/2025
Locations: Prentice Women's Hospital, Chicago, Illinois
Conditions: E. Coli Infection, Multi-antibiotic Resistance
Register for Updates