Illinois is currently home to 2668 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Novel Probiotic-antibiotic Combination to Prevent Recurrent Urinary Tract Infections
NCT06149676
Recruiting
Patients with recurrent UTI were randomized to receive either the probiotic Sacchromyces Boulardii at enrollment, and the intracellularly active Ciprofloxacin with their first UTI episode after enrollment, or they received standard of care treatment.
Gender:
ALL
Ages:
Between 2 years and 17 years
Trial Updated:
01/14/2025
Locations: Lurie Children's Hospital, Chicago, Illinois
Conditions: Recurrent Uti
Register for Updates
Breast Cancer Pre-habilitation and Prospective Surveillance to Prevent, Detect, and Optimize Physical and Function
NCT06081127
Recruiting
The goal of this research study is to determine the feasibility and potential effects of physical therapy and enhanced patient education delivered before breast cancer treatment. Physical therapy before cancer treatment aims to help with early identification and self-management of physical and functional side effects from cancer treatment. Side effects could be joint pain, muscle weakness, or fatigue that contribute to functional impairment. The main questions this study aims to answer are: 1.... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Breast Cancer
Register for Updates
My Wellbeing Guide: a Novel Tool for Managing Stress and Improving Quality of Life
NCT05369429
Recruiting
The purpose of this study is to examine the implementation and effectiveness of the psychosocial eHealth intervention, My Wellbeing Guide, on the proposed primary outcome, depressive symptoms, in patients diagnosed with cancer who receive care at Northwestern Medicine and the University of Miami Health System. Eligible patients will be directly contacted by the study team for recruitment. The intervention includes cognitive behavioral therapy management strategies for health-related stress in t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Cancer, Anxiety, Depressive Symptoms
Register for Updates
Church-based Intervention to Improve Blood Pressure in African Americans
NCT05220332
Recruiting
This is a 12-month behavioral cluster-randomized trial testing a church-based intervention to reduce blood pressure in African Americans with uncontrolled blood pressure.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Hypertension
Register for Updates
Comparison of Partial Rotator Cuff Repair vs. Superior Capsular Reconstruction for Irreparable Rotator Cuff Tears
NCT04742452
Recruiting
The primary objective of this prospective randomized controlled trial is to compare pain and functional outcomes between two surgical modalities for irreparable rotator cuff tears as measured by the pain visual analog scale (VAS), simple shoulder test (SST), American Shoulder and Elbow Surgery shoulder score (ASES), and Patient Reported Outcomes Measurement Information System (PROMIS) 29 score at 6 weeks, 3, 6, 12, and 24 months post-operatively. The two surgical modalities of interest are parti... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
01/14/2025
Locations: Midwest Orthopaedics at Rush, Chicago, Illinois
Conditions: Rotator Cuff Tears
Register for Updates
GORE® ENFORM Biomaterial Product Study
NCT04718168
Recruiting
A prospective, retrospective, non-randomized, multicenter study with two independent hernia study cohorts (Ventral / Incisional Hernia Repair and Diaphragmatic / Hiatal Hernia Repair). The primary objective of this study is to collect GORE® ENFORM Biomaterial product commercial-use data on device functional performance and short-term patient experience.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/14/2025
Locations: Northshore University Health System Research Institute, Evanston, Illinois
Conditions: Hernia, Hiatal, Hernia, Diaphragmatic, Hernia, Ventral, Incisional Hernia
Register for Updates
Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
NCT06639503
Recruiting
The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the participant surgical incision. The investigators hope to discover if providing numbing medication to a nerve that controls pain in a larger area of the knee (a nerve block), might be better at post-operative pain control.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Tibial Plateau Fractures
Register for Updates
Lynch Syndrome Integrative Epidemiology and Genetics
NCT06582914
Recruiting
The vision of the "Lynch syndrome INtegrative Epidemiology And GEnetics" (LINEAGE) Consortium is to collaboratively improve the lives and longevity of individuals and families with Lynch syndrome. The mission of the LINEAGE Consortium is to collaboratively improve Lynch syndrome care through high-quality research. This consortium will provide intellectual and infrastructure support to facilitate development of research questions, collection of standardized data and biospecimens, support of gran... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Lynch Syndrome
Register for Updates
Effect of Cooling Therapy for Post-Operative Pain in Open Carpal Tunnel Release
NCT05783245
Recruiting
This study seeks to perform an appropriately-powered study to evaluate any clinical difference between continuous cooling therapy and traditional ice for treatment of post-operative pain in open CTR surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: University of Chicago Medicine, Chicago, Illinois
Conditions: Carpal Tunnel Syndrome, Perioperative/Postoperative Complications
Register for Updates
Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer
NCT04918186
Recruiting
This study is being done to answer the following question: What are the effects of a new drug or drugs on ovarian cancer? The pre-study screening may be done to test a sample of tissue for biomarkers to determine participation in the study.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: The University of Chicago Medical Center, Chicago, Illinois
Conditions: Ovarian Cancer
Register for Updates
NBTXR3 Activated by Radiotherapy for Patients with Advanced Cancers Treated with an Anti-PD-1 Therapy
NCT03589339
Recruiting
The 1100 study is an open-label, Phase I, dose escalation and expansion prospective clinical study to assess the safety of intratumoral injection of NBTXR3 activated by radiotherapy in combination with anti-PD-1 therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/13/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Radiotherapy, Immunotherapy, Microsatellite Instability-High Solid Malignant Tumour, Squamous Cell Carcinoma of Head and Neck, Metastasis From Malignant Tumor of Cervix, Metastasis From Malignant Melanoma of Skin (Disorder), Metastasis From Malignant Tumor of Bladder (Disorder), Metastasis From Malignant Tumor of Liver, Metastatic Renal Cell Carcinoma, Metastatic Triple-Negative Breast Carcinoma, Metastatic NSCLC
Register for Updates
Objective Assessment of Outcomes Following Immediate Lymphatic Reconstruction / LYMPHA
NCT06650592
Recruiting
Immediate lymphatic reconstruction (ILR) is a novel surgical approach performed at the time of initial lymph node dissection with the goal of preventing lymphedema. It involves the identification of lymphatic channels that are transected after lymph node dissection and microsurgical anastomosis of one or more lymphatic channel with a local recipient vein to re-direct upper extremity lymphatic drainage. Although ILR carries significant promise in prevention of lymphedema, there is a lack of high-... Read More
Gender:
ALL
Ages:
All
Trial Updated:
01/10/2025
Locations: The University o Chicago, Chicago, Illinois
Conditions: Lymphatic Reconstruction
Register for Updates