Illinois is currently home to 2637 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Training for Urinary Leakage Improvement After Pregnancy
NCT06411158
Recruiting
This is a multi-center, randomized single-blind nonsurgical trial conducted in approximately 216 primiparous postpartum women at high risk for prolonged/sustained pelvic floor disorders with symptomatic, bothersome urinary incontinence (UI) amenable to nonsurgical treatment. TULIP is a 3-Arm trial with two active interventions (Arms 1 and 2) and a Patient Education control arm (Arm 3). Arm 1 consists of pelvic floor muscle training (PFMT). Arm 2 uses a home biofeedback device (leva®). The prim... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Urinary Incontinence, Delivery Complication
Register for Updates
Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR
NCT06376916
Recruiting
The purpose of this prospective, randomized, double-blinded study is to further evaluate the safety and efficacy of varying doses of intravenous magnesium in the treatment of AFF RVR.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Advocate Christ Medical Center Emergency Department (ACMC ED), Oak Lawn, Illinois
Conditions: Tachycardia Atrial, Atrial Fibrillation, Atrial Flutter With Rapid Ventricular Response
Register for Updates
Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients with Sickle Cell Disease
NCT05861453
Recruiting
To assess the pharmacokinetics, pharmacodynamics and safety of Epeleuton capsules in adult SCD patients who are aged ≥18 years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: UI Health Sickle Cell Center, Chicago, Illinois
Conditions: Sickle Cell Disease
Register for Updates
Eosinophilic Gastrointestinal Disorders Registry
NCT05199532
Recruiting
The purpose of this study is to learn more about Eosinophilic Gastrointestinal Disorders (EGIDs). With this registry we hope to find out more about the symptoms that patients have during their treatment, the quality of life they have with the diagnosis, what the disease looks like throughout the different treatment methods, and if there is a connection between EGIDs and connective tissue disorders. The goal of this study is to be able to better understand EGIDs and use information gained from a... Read More
Gender:
ALL
Ages:
Between 1 year and 25 years
Trial Updated:
11/13/2024
Locations: Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Eosinophilic Esophagitis, Eosinophilic Gastroenteritis, Eosinophilic Colitis, Eosinophilic Gastrointestinal Disease
Register for Updates
Atypical Hemolytic-Uremic Syndrome (aHUS) Registry
NCT01522183
Recruiting
Post-marketing safety data on patients treated and untreated with eculizumab or ravulizumab.
Gender:
ALL
Ages:
All
Trial Updated:
11/13/2024
Locations: Clinical Trial Site, Chicago, Illinois
Conditions: Atypical Hemolytic-Uremic Syndrome
Register for Updates
Bowel Dysfunction and HoLEP Outcomes
NCT06688500
Recruiting
The objective of this prospective study is to examine the correlation and effects of bowel dysfunction on outcomes for patients undergoing holmium laser enucleation of prostate (HoLEP) for lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH).The investigator hypothesizes that patients who have more bowel dysfunction based on higher severity scores on patient-reported validated questionnaires will experience more symptoms in the immediate post-operative period and may have... Read More
Gender:
MALE
Ages:
Between 18 years and 89 years
Trial Updated:
11/12/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Urologic Injuries
Register for Updates
A Study to Assess How the Drug Moves Through the Body, Adverse Events, and Tolerability of Oral ABBV-722 Capsules of Single and Multiple Ascending Doses in Adult Participants and Single Doses in Adult Asian Participants
NCT06673238
Recruiting
This is a Phase 1, first-in-human study to investigate safety, tolerability, and pharmacokinetics of ABBV-722 after oral dosing in healthy adult participants.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/12/2024
Locations: Acpru /Id# 270279, Grayslake, Illinois
Conditions: Healthy Volunteer
Register for Updates
Laser Outcomes Associated With (Holmium Laser Enucleation of the Prostate) HoLEP Procedures
NCT06531473
Recruiting
The primary aim is to assess the impact of laser setting frequency and wattage during holmium laser enucleation of the prostate. There is currently no gold-standard laser settings for HoLEP procedures. In the investigator's current high-volume practice, the following settings for enucleation are: 2j 50hz. These settings are conventional settings, but there is no literature to prove optimal laser settings. The investigators hypothesizes that utilization of higher laser settings may be associated... Read More
Gender:
MALE
Ages:
Between 18 years and 89 years
Trial Updated:
11/12/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Urologic Diseases, Prostate Obstruction
Register for Updates
Segmentectomy After Induction Therapy (SAINT)
NCT06496659
Recruiting
The primary objective will be to determine the feasibility of performing a high-quality sublobar anatomic resection (segmentectomy) with R0 margin status on final pathology for patients who received induction therapy for NSCLC and are downstaged to ≤ycT1cN0M0 (TDi 3cm or less). T1c is tumor staging 1 and c stands for tumor is considered larger than 2cm but no larger than 3cm across; N0 is No regional lymph node metastasis; M0 is No distant metastasis.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
11/12/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Segmentectomy
Register for Updates
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
NCT06426628
Recruiting
The goal of this observational study is to learn how a physician uses the results of the Percepta® Nasal Swab test to manage people with a newly identified pulmonary nodule. The main questions it aims to answer are: * Does the use of the Percepta Nasal swab test reduce the number of invasive procedures in people with a low-risk result and whose nodule is benign? * Does the use of the Percepta Nasal swab test decrease the time to treatment in people with a high-risk result and whose nodule is c... Read More
Gender:
ALL
Ages:
Between 29 years and 85 years
Trial Updated:
11/12/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Pulmonary Nodule, Solitary, Lung Cancer
Register for Updates
Resilience in East Asian Immigrants for Advance Care Planning Discussions
NCT06035549
Recruiting
The purpose of the study is to develop a culturally tailored digital resilience-building intervention to help East Asian immigrants engage in advance care planning discussions with their family caregivers.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/12/2024
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Neoplasms, Advance Care Planning
Register for Updates
Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: a Pilot Project
NCT06004674
Recruiting
The goal of this randomized clinical trial is to evaluate if we can use placental pathology in a prior pregnancy which had an adverse outcome, such as early delivery, stillbirth, a baby born smaller than expected, or severe forms of high blood pressure during pregnancy, to guide treatment in the subsequent pregnancy and reduce risk of recurrent adverse pregnancy events. The main questions it aims to answer are: * Whether enoxaparin prevents recurrent adverse pregnancy outcomes among patients w... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
11/12/2024
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: Adverse Pregnancy Outcome
Register for Updates