Illinois is currently home to 2668 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
Recruiting
Durable left ventricular assist devices (dLVAD) have been increasingly utilized since the mid to late 1990s, with an uptick of utility starting in 2010 following expanded indications for therapy to not only include a bridge to transplantation strategy, but also for those individuals who suffer from advanced heart failure (HF) and do not qualify for cardiac transplantation. Despite the decreasing size of the newest generation devices leading to a lessened occurrence of adverse events, bleeding an... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/08/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: LVAD, Frailty, GI Bleed, Right Heart Failure, Infections, Hypertension, Arrhythmias, Stroke
R01.Aim 2.Study 1: IsoReach
Recruiting
To determine the effects of 3D isometric movement training in healthy participants and impaired participants due to a stroke.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/07/2025
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Stroke
Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors
Recruiting
The purpose of this study is to evaluate the safety, feasibility, and efficacy of an exoskeletal network of passive, multi-joint springs for forearm supination. Also known as the forearm ExoNET, the device is a passive, robotic device that will properly assist forearm supination in the post-stroke adult population.
Gender:
ALL
Ages:
Between 40 years and 70 years
Trial Updated:
01/07/2025
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Stroke, Cerebral Vascular Accident
Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy
Recruiting
Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention that identifies hospitalized African Americans with advanced chronic kidney disease (CKD) and provides them with hospital- and community-based education, navigation and self-management support. Participants will be randomized to the iPREP-RRT intervention versus enhanced usual care.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
01/07/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Chronic Kidney Disease, Hypertension
Interactive Computer-adaptive Chronic Kidney Disease Education Program
Recruiting
The goal of this pilot clinical trial is to evaluate a culturally tailored computerized education program in hospitalized African-American patients with advanced chronic kidney disease (CKD). The main question it aims to answer are: does computerized adaptive education (CAE) increase patients' knowledge about CKD self-care and renal replacement therapy (RRT) options compared to usual care (UC) and will CAE will be increase patients' intent to participate in CKD self-care and RRT preparation comp... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
01/07/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Chronic Kidney Diseases, Hypertension
Prospective Validation Study of High Volume Urine DNA Testing in Individuals with Suspicion of Urothelial Cancer
Recruiting
Urothelial cancers of the bladder and upper urinary tract account for over 200,000 deaths and 600,000 diagnoses annually worldwide. The most common presenting symptom is hematuria (blood in urine), triggering a cascade of tests, including an invasive examination of the bladder using a flexible scope (cystoscopy). Millions of cystoscopies are performed every year worldwide for patients presenting with hematuria, but only 10% result in a cancer diagnosis. The UROSCOUT-1 trial is a prospective mult... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/07/2025
Locations: Jesse Brown Department Of Veterans Affairs Medical Center, Chicago, Illinois
Conditions: Urothelial Carcinoma
Improvement of Hyperglycemia/Diabetes in Patients to Improve Safety
Recruiting
The goal of this project is to bring together staff and clinicians from Northwestern University/Northwestern Medical Group/Northwestern Memorial Hospital as well as patients and caregivers to assess and redesign the identification and management of hyperglycemia and diabetes during and in transitions of care. There will be 3 different groups for the study: a group of providers \[Group 1\], a group of patients/caregivers and laypersons \[Group 2\], and a stakeholder group \[Group 3\]. Participant... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/07/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Diabetes Mellitus, Type 2
Empowering Vulnerable and Resilient Latinas to Obtain Breast Cancer Care
Recruiting
The investigator and study staff will identify, recruit and randomize Latina participants with elevated genetic and Social Determinants of Heath (SDH) risks. Within 1 week of enrollment, all Latina Aim 1 participants in both study arms will engage in three 30-minute, individual, phone-based sessions with the study team across 3 consecutive weeks
Gender:
FEMALE
Ages:
30 years and above
Trial Updated:
01/07/2025
Locations: University of Illinois, Chicago, Illinois
Conditions: Breast Cancer
Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities
Recruiting
This is a pivotal, prospective, multi-center, randomized, concurrent control, patient and assessor-blinded study with two arms: a treatment arm (where subjects will be treated with the EP Granules with Tobramycin investigational device in the 1st stage of a staged revision for periprosthetic joint infection (PJIs), and a control arm (where subjects are treated with the standard-of-care revision for infected PJIs).
Gender:
ALL
Ages:
22 years and above
Trial Updated:
01/07/2025
Locations: Endeavor Health Skokie Hospital, Skokie, Illinois
Conditions: Periprosthetic Joint Infections
Intrathecal Morphine for Analgesia in Video-assisted Thoracic Surgery
Recruiting
VATS is widely used for diagnosis and treatment of intrathoracic conditions. Despite many benefits, postoperative pain continues to be intense after VATS. The optimal strategy for pain management has not been defined. In this randomized, placebo-controlled, double-blinded clinical investigation, investigators hypothesize that 5 mcg/kg intrathecal morphine will decrease postoperative analgesic consumption and reduce pain.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
01/07/2025
Locations: University of Chicago, Chicago, Illinois
Conditions: Pain, Postoperative
Surgical Treatments for Postamputation Pain
Recruiting
This is a double-blind randomised controlled trial (RCT) which compares the effectiveness of three surgical techniques for alleviating residual limb pain (RLP), neuroma pain and phantom limb pain (PLP). The three surgical treatments are Targeted Muscles Reinnervation (TMR), Regenerative Peripheral Nerve Interface (RPNI), and an active control (neuroma excision and muscle burying). Patients will be follow-up for 4 years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/07/2025
Locations: Northwestern Memorial Hospital, Chicago, Illinois
Conditions: Amputation Neuroma, Phantom Limb Pain, Pain, Neuropathic, Pain, Nerve, Residual Limb Pain
Blood Flow Restriction Following Hip Arthroscopy
Recruiting
This study will be a prospective randomized, double-blinded, placebo-controlled trial of patients undergoing primary hip arthroscopy for FAIS and/or labral pathology. All patients who sign the consent form will be enrolled in the study and randomized to one of the two treatment arms. Follow-up will take place at 1-month, 3-months, 6-months, and 1-year.
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
01/07/2025
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Labral Tear, Glenoid, Femoral Acetabular Impingement