Illinois is currently home to 2661 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)
NCT04187105
Recruiting
Pre-transplant conditioning will include targeted total marrow irradiation (TMI) at a dose of 6Gy. Graft-versus-host disease prophylaxis will include cyclophosphamide 50 mg/kg on Day +3 and 4 along with tacrolimus and mycophenolate mofetil
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
12/11/2024
Locations: University of Illinois Cancer Center, Chicago, Illinois
Conditions: Acute Leukemia, MDS
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The Effect of Cupping on Spasticity and Function of the Lower Extremity During Rehabilitation After Stroke
NCT06653855
Recruiting
Physical therapists use dry static cupping for the treatment of many conditions, including spasticity for patients post-stroke. While research better describes the effects of dry static cupping for patients with orthopedic conditions, information is lacking on central conditions, such as stroke and resulting spasticity.
Gender:
ALL
Ages:
Between 30 years and 80 years
Trial Updated:
12/10/2024
Locations: Ascension Rehabilitation of Joliet, Joliet, Illinois
Conditions: Stroke Gait Rehabilitation
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Oral Iron Supplementation on Alternate Vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy
NCT06492512
Recruiting
This will be a randomized clinical trial. Enrolled subjects will be randomized (1:1) into two study arms to receive either daily (Group 1) or alternate day (Group 2) supplementation with one oral pill containing ferrous sulfate with an equivalent elemental iron dose of 65 mg per pill.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
12/10/2024
Locations: Southern Illinois University School of Medicine, Springfield, Illinois
Conditions: Iron-deficiency Anemia (IDA), Pregnancy
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Investigational MRI Clinical Software and Hardware
NCT05215132
Recruiting
Patients and healthy volunteers will be scanned in order to test new sequences.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
12/10/2024
Locations: Northwestern University- Feinberg School of Medicine, Chicago, Illinois
Conditions: Image, Body
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Noninvasive Brain Stimulation in Adult Amblyopia
NCT06712849
Recruiting
The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1. What are the effects of non-invasive brain stimulation on neuronal plasticity in the visual cortex of adults with amblyopia, and does it produce lasting changes? 2. Do cumulative sessions of non-invasive brain stimulation influence neural plasticity and higher-order visual functions in adults with ambly... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
12/09/2024
Locations: Midwestern University Eye Institute, Downers Grove, Illinois
Conditions: Amblyopia
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The NaBu Effect on Menstruation in Women
NCT06653426
Recruiting
The purpose of this study is to evaluate the effect of once-daily Sodium butyrate (NaBu) on menstrual symptoms in women. The investigators posit that the use of NaBu will reduce menstrual symptoms after taking NaBu for 12 weeks.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/09/2024
Locations: Northwestern University - Northwestern Medicine, Lavin Family Pavilion, Chicago, Illinois
Conditions: Menstrual Symptoms
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Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL
NCT05289687
Recruiting
In this study, the investigators are hypothesizing that daratumumab-hyaluronidase will effectively treat T-ALL in patients who have persistent or recurrent MRD following treatment with chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/09/2024
Locations: Northwestern, Chicago, Illinois
Conditions: T-cell Acute Lymphoblastic Leukemia
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Utilization of a Videoscope in Periodontal Regeneration
NCT05275192
Recruiting
Clinical and preclinical studies confirm that regeneration of supporting tissues of teeth lost due to periodontal disease can be achieved using the principles of minimally invasive surgery (MIS). Although this therapeutic approach is well established in clinical settings and can rescue teeth with poor or questionable prognosis, MIS approaches often suffer from lack of predictability due to poor intraoral visibility of the bony lesion and inability to confirm thorough removal of etiological facto... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
12/09/2024
Locations: University of Illinois, Chicago, College of Dentistry, Periodontics, Chicago, Illinois
Conditions: Chronic Periodontitis
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Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System
NCT03831386
Recruiting
Malignant pleural effusion remains a debilitating complication of end stage cancer, which can be greatly improved by the introduction of the indwelling tunneled pleural catheter (IPC). However, there is no standard of care regarding drainage and limited data on the utility of different drainage techniques. In addition, many patients develop discomfort and chest pain during drainage. The investigators propose to evaluate gravity drainage and suction drainage on quality of life measures and outcom... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/09/2024
Locations: Northwest Community Healthcare, Arlington Heights, Illinois
Conditions: Pleural Effusion
Register for Updates
Phase 1 Study of INBRX-109 in Subjects with Locally Advanced or Metastatic Solid Tumors Including Sarcomas
NCT03715933
Recruiting
This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody targeting the human death receptor 5 (DR5).
Gender:
ALL
Ages:
Between 12 years and 85 years
Trial Updated:
12/09/2024
Locations: The University of Chicago, Chicago, Illinois
Conditions: Colorectal Adenocarcinoma, Ewing Sarcoma
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A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRĪ±)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
NCT04300556
Recruiting
The primary objectives of the study are: (1) in the dose-escalation part: to evaluate safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of farletuzumab ecteribulin (MORAb-202) in participants with selected tumor types (ovarian cancer \[OC\], endometrial cancer \[EC\], non-small cell lung carcinoma \[NSCLC\], triple-negative breast cancer \[TNBC\]), and (2) in dose-confirmation part: to evaluate preliminary efficacy measured by objective response rate (ORR) of farletuzu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/06/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Solid Tumor
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Brain Oxygen Optimization in Severe TBI, Phase 3
NCT03754114
Recruiting
BOOST3 is a randomized clinical trial to determine the comparative effectiveness of two strategies for monitoring and treating patients with traumatic brain injury (TBI) in the intensive care unit (ICU). The study will determine the safety and efficacy of a strategy guided by treatment goals based on both intracranial pressure (ICP) and brain tissue oxygen (PbtO2) as compared to a strategy guided by treatment goals based on ICP monitoring alone. Both of these alternative strategies are used in s... Read More
Gender:
ALL
Ages:
14 years and above
Trial Updated:
12/06/2024
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Brain Injuries, Traumatic
Register for Updates