Illinois is currently home to 2661 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR
NCT06376916
Recruiting
The purpose of this prospective, randomized, double-blinded study is to further evaluate the safety and efficacy of varying doses of intravenous magnesium in the treatment of AFF RVR.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: Advocate Christ Medical Center Emergency Department (ACMC ED), Oak Lawn, Illinois
Conditions: Tachycardia Atrial, Atrial Fibrillation, Atrial Flutter With Rapid Ventricular Response
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Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients with Sickle Cell Disease
NCT05861453
Recruiting
To assess the pharmacokinetics, pharmacodynamics and safety of Epeleuton capsules in adult SCD patients who are aged ≥18 years.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/13/2024
Locations: UI Health Sickle Cell Center, Chicago, Illinois
Conditions: Sickle Cell Disease
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Eosinophilic Gastrointestinal Disorders Registry
NCT05199532
Recruiting
The purpose of this study is to learn more about Eosinophilic Gastrointestinal Disorders (EGIDs). With this registry we hope to find out more about the symptoms that patients have during their treatment, the quality of life they have with the diagnosis, what the disease looks like throughout the different treatment methods, and if there is a connection between EGIDs and connective tissue disorders. The goal of this study is to be able to better understand EGIDs and use information gained from a... Read More
Gender:
ALL
Ages:
Between 1 year and 25 years
Trial Updated:
11/13/2024
Locations: Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Eosinophilic Esophagitis, Eosinophilic Gastroenteritis, Eosinophilic Colitis, Eosinophilic Gastrointestinal Disease
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Atypical Hemolytic-Uremic Syndrome (aHUS) Registry
NCT01522183
Recruiting
Post-marketing safety data on patients treated and untreated with eculizumab or ravulizumab.
Gender:
ALL
Ages:
All
Trial Updated:
11/13/2024
Locations: Clinical Trial Site, Chicago, Illinois
Conditions: Atypical Hemolytic-Uremic Syndrome
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Bowel Dysfunction and HoLEP Outcomes
NCT06688500
Recruiting
The objective of this prospective study is to examine the correlation and effects of bowel dysfunction on outcomes for patients undergoing holmium laser enucleation of prostate (HoLEP) for lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH).The investigator hypothesizes that patients who have more bowel dysfunction based on higher severity scores on patient-reported validated questionnaires will experience more symptoms in the immediate post-operative period and may have... Read More
Gender:
MALE
Ages:
Between 18 years and 89 years
Trial Updated:
11/12/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Urologic Injuries
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Laser Outcomes Associated With (Holmium Laser Enucleation of the Prostate) HoLEP Procedures
NCT06531473
Recruiting
The primary aim is to assess the impact of laser setting frequency and wattage during holmium laser enucleation of the prostate. There is currently no gold-standard laser settings for HoLEP procedures. In the investigator's current high-volume practice, the following settings for enucleation are: 2j 50hz. These settings are conventional settings, but there is no literature to prove optimal laser settings. The investigators hypothesizes that utilization of higher laser settings may be associated... Read More
Gender:
MALE
Ages:
Between 18 years and 89 years
Trial Updated:
11/12/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Urologic Diseases, Prostate Obstruction
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Segmentectomy After Induction Therapy (SAINT)
NCT06496659
Recruiting
The primary objective will be to determine the feasibility of performing a high-quality sublobar anatomic resection (segmentectomy) with R0 margin status on final pathology for patients who received induction therapy for NSCLC and are downstaged to ≤ycT1cN0M0 (TDi 3cm or less). T1c is tumor staging 1 and c stands for tumor is considered larger than 2cm but no larger than 3cm across; N0 is No regional lymph node metastasis; M0 is No distant metastasis.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
11/12/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Segmentectomy
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Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
NCT06426628
Recruiting
The goal of this observational study is to learn how a physician uses the results of the Percepta® Nasal Swab test to manage people with a newly identified pulmonary nodule. The main questions it aims to answer are: * Does the use of the Percepta Nasal swab test reduce the number of invasive procedures in people with a low-risk result and whose nodule is benign? * Does the use of the Percepta Nasal swab test decrease the time to treatment in people with a high-risk result and whose nodule is c... Read More
Gender:
ALL
Ages:
Between 29 years and 85 years
Trial Updated:
11/12/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Pulmonary Nodule, Solitary, Lung Cancer
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Resilience in East Asian Immigrants for Advance Care Planning Discussions
NCT06035549
Recruiting
The purpose of the study is to develop a culturally tailored digital resilience-building intervention to help East Asian immigrants engage in advance care planning discussions with their family caregivers.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/12/2024
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Neoplasms, Advance Care Planning
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RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer
NCT05966194
Recruiting
The purpose of this study is to determine if RRx-001, which is added on to the cisplatin and radiation treatment, reduces the incidence of severe oral mucositis in patients with head and neck cancers. All patients in this study will receive 7 weeks of standard of care radiation therapy given with the chemotherapy agent, cisplatin. Patients will receive RRx-001 or placebo before start of standard of care treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/12/2024
Locations: Northwestern University Feinberg School of Medicine, Chicago, Illinois
Conditions: Oral Mucositis
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Investigating Outcomes of Elective Robotic Transhiatal Esophagectomy
NCT05950438
Recruiting
The primary goal of this study is to collect short-term and long-term health outcomes of a robotic transhiatal esophagectomy procedure. Clinical (or health) outcomes measure the effect of the procedure on your overall health status. During this procedure, the surgeon will remove all or part of your esophagus. We want to identify patients who will have this procedure. We will look at data elements before, during, and after your procedure to understand the impact of this surgery on your post-opera... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
11/12/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Esophagectomy
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DREAM: Double Lung Transplant REgistry Aimed for Lung-limited Malignancies
NCT05671887
Recruiting
This is a prospective observational registration trial for patients who undergo lung transplantation for the treatment of the select groups of medically refractory cancers affecting the lungs alone without extrapulmonary nodal and distant metastasis.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/12/2024
Locations: Thoracic Surgery, Canning Thoracic Institute (Northwestern Memorial Hospital), Chicago, Illinois
Conditions: Lung Cancer, Bilateral Cancer, Lung Transplant
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