Illinois is currently home to 2681 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Personalized GI Motility Responses to Diet
Recruiting
The goal of this randomized, crossover, clinical trial is to link: 1) gastrointestinal motility patterns induced by acute consumption of whole and refined grains, 2) enteric microbial production of bioactive metabolites, and 3) circulating postprandial appearance of metabolites important to cardiometabolic health including glucose, triglycerides, and cholesterol. Participants will be asked to consume a Smartpill monitoring device that records metrics of gastrointestinal motility in response to... Read More
Gender:
All
Ages:
Between 21 years and 63 years
Trial Updated:
04/23/2024
Locations: University of Illinois at Urbana-Champaign, Urbana, Illinois
Conditions: Nutritional and Metabolic Diseases, Gastrointestinal Dysfunction, Cardiovascular Diseases, Dysbiosis
An Electronic Health Record-based Approach to Increase PrEP Knowledge and Uptake: the EMC2 PrEP Strategy
Recruiting
This study is being conducted to investigate a strategy that may improve knowledge and uptake of pre-exposure prophylaxis for HIV prevention (PrEP) among cisgender women in primary care.
Gender:
Female
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: HIV Infections, Electronic Health Record, Primary Health Care
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.
Recruiting
This is a Phase 1, multi-center, open-label study with a dose-escalation phase (Phase 1a) and a cohort expansion phase (Phase 1b), to evaluate the safety, tolerability, and PK profile of LP-118 under a once daily oral dosing schedule in up to 100 subjects.
Gender:
All
Ages:
13 years and above
Trial Updated:
04/23/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Non Hodgkin Lymphoma, Richter Transformation, Multiple Myeloma, T-cell-prolymphocytic Leukemia, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Myeodysplastic Syndrome, Myelofibrosis, Myelodysplastic/Myeloproliferative Neoplasm, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Chronic Myelomonocytic Leukemia-2, Myelodysplastic Neoplasm in Blast Phase
Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease
Recruiting
The goal of this observational study is to help us understand more about the best ways to help individuals living with Sickle Cell Disease (SCD) get the best care. The main question it aims to answer is: How to find individuals unaffiliated from SCD specialist care use three distinct pathways? Once unaffiliated individuals are found using the pathways, Investigators will employ linkage coordinators (trained staff) to engage these patients in care. Participants will be asked to fill out an assess... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: University of Illinois, Chicago, Illinois
Conditions: Sickle Cell Disease
Neurocognitive Mechanisms of Perimenstrual Estrogen Effects on Suicidality
Recruiting
This within-person, crossover, 2-condition, placebo-controlled study compares the impact of two perimenstrual conditions on severity of suicidal symptoms in females with past-month suicidality but minimal risk of imminent suicide attempt. The two conditions are (1) perimenstrual administration of estradiol and (2) natural perimenstrual withdrawal from estradiol during placebo.
Gender:
Female
Ages:
Between 20 years and 40 years
Trial Updated:
04/22/2024
Locations: University of Illinois Neuropsychiatric Institute, Chicago, Illinois
Conditions: Suicide
Phenotyping Adherence Through Technology-Enabled Reports and Navigation
Recruiting
This study is being conducted to adapt and pilot test a technology-enabled, primary care strategy for routinely monitoring medication use and adherence among older adults with multiple chronic conditions and polypharmacy.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/22/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Medication Adherence
Surgery Versus Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer
Recruiting
The development of stereotactic body radiation therapy (SBRT) for the treatment of stage I non-small cell lung cancer (NSCLC) has inspired a close partnership between thoracic surgery and radiation oncology. In this study, patients with stage I NSCLC will be screened prior to treatment and will be consented after their treatment plan has been determined. Prospectively collected patient-reported outcomes (PROs) will be collected for 3 years, as will outcomes data.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: Carle Cancer Institute, Urbana, Illinois
Conditions: Non Small Cell Lung Cancer, Non-small Cell Lung Cancer
Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus
Recruiting
Esophageal cancer is a deadly disease that is becoming increasingly common in the United States. Barrett's esophagus (BE) is a pre-cancerous state that can develop into esophageal cancer, but is highly treatable. Progression of BE to esophageal cancer is still common due to missed diagnosis of Barrett's esophagus recurrence following treatment. Wide-Area Trans-Epithelial Sampling (WATS-3D) is a new technology that uses brush sampling to examine larger areas of the esophagus as compared to conven... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: Northwestern Memorial Hospital, Chicago, Illinois
Conditions: Barrett Esophagus, Esophageal Cancer
Viral Infection and Respiratory Illness Universal Study[VIRUS]: COVID-19 Registry
Recruiting
Researchers are creating a real time COVID-19 registry of current ICU/hospital care patterns to allow evaluations of safety and observational effectiveness of COVID-19 practices and to determine the variations in practice across hospitals.
Gender:
All
Ages:
All
Trial Updated:
04/22/2024
Locations: Society of Critical Care Medicine (150+ sites), Chicago, Illinois
Conditions: Coronavirus
The Effect of IBD Flares on Serum PSA
Recruiting
This study will measure Prostate Specific Antigen (PSA) values in men with Inflammatory Bowel Disease (IBD) before, during, and following a flare. In addition, the effect of any PSA increase will be analyzed and correlated to the location of disease (rectal vs. other). Study findings may help men with IBD by identifying pitfalls in prostate cancer screening for this population and help to stratify and understand the effect IBD has on the prostatic milieu. By optimizing how men with IBD are scree... Read More
Gender:
Male
Ages:
Between 40 years and 69 years
Trial Updated:
04/22/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Inflammatory Bowel Diseases, Prostate Cancer
Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)
Recruiting
This is an 8-week, double-blind, randomized placebo-controlled trial of the efficacy of a combination of extended-release naltrexone (XR-NTX) and extended-release buprenorphine (XR-BUP) compared to matched placebo injections (PBO-Inj) for the treatment of cocaine use disorder (CUD).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/19/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Cocaine Use Disorder
Low Cost Socket for Lower Limb Amputees
Recruiting
The purpose of this research is to test an investigational fabrication system for transtibial prostheses. This fabrication method will be tested for comfort and function to determine feasibility of use for amputees in developing countries. To address the need for high quality and affordable prosthetic technology in developing countries, the investigators have developed a simplified socket fitting protocol using expandable rigid foam. The foam is formed by mixing small amounts of two liquid comp... Read More
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
04/19/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Amputation, Amputation; Traumatic, Limb, Amputation, Traumatic