Illinois is currently home to 2616 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Safety and Efficacy of Venetoclax With Escalating Doses of Omacetaxine in Patients With Acute Myeloid Leukemia Safety and Efficacy of Venetoclax With Escalating Doses of Omacetaxine in Patients With Acute Myeloid Leukemia (AML)
NCT04926285
Recruiting
This will be a single arm, open label Phase Ib dose-escalation study of the combination of VEN and OM, conducted using an innovative Bayesian Optimal Interval-design, to find the MTD in participants with AML failing treatment with venetoclax-containing regimens. Treatment plan will consist of an induction phase, followed by a consolidation phase if applicable.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/30/2024
Locations: University of Illinois Cancer Center, Chicago, Illinois
Conditions: Relapsed or Refractory Hematologic Malignancies
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Optimization of NIBS for Treatment of Addiction
NCT04379115
Recruiting
The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate use disorder with chronic pain. The investigators hypothesize that there will be a decrease in drug use and improved psychosocial assessments with active stimulation, when compared to sham stimulation.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
05/30/2024
Locations: University of Illinois Health/ University of Illinois at Chicago, Hinsdale, Illinois
Conditions: Opioid-use Disorder, Chronic Pain
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Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas
NCT02598349
Recruiting
The prognosis for patients with localized pancreatic adenocarcinoma who are not surgical candidates is poor. Patients characterized as having "borderline resectable" disease treated with preoperative chemo-radiotherapy fair somewhat better - although many of these patients are not converted to resectability. It may be argued that intensification of local and regional therapy might 1.) Increase the share of patients able to undergo curative surgery and 2.) Improve the local disease control interv... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/30/2024
Locations: Northwestern Medicine Chicago Proton Center, Warrenville, Illinois
Conditions: Pancreatic Cancer
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Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
NCT01766297
Recruiting
The purpose of this research study is to compare the effects (good and bad) on women and their cancer using proton radiation therapy. This study is being done to see if proton radiation therapy will prove to be beneficial for women with early stage breast cancer. A clinical study is necessary to compare the results (good or bad) of proton radiation therapy.
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
05/30/2024
Locations: Northwestern Medicine Chicago Proton Center, Warrenville, Illinois
Conditions: Breast Cancer, Breast Neoplasm, Breast Tumor, Cancer of the Breast
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Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer
NCT01492972
Recruiting
The purpose of this study is to compare the effects, good and/or bad of two treatment methods on subjects and their cancer. Proton beam radiation therapy is one of the treatments for men with prostate cancer who have localized disease. The benefit of the combination with androgen suppression is not completely understood. This study will compare the use of hypofraction proton therapy (28 treatments) alone to proton therapy with androgen suppression therapy.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
05/30/2024
Locations: Northwestern Medicine Chicago Proton Center, Warrenville, Illinois
Conditions: Prostate Cancer
Register for Updates
Registry Study for Radiation Therapy Outcomes
NCT01255748
Recruiting
The purpose of this research study is to collect and analyze information from patients being treated with various forms of radiation therapy.
Gender:
ALL
Ages:
All
Trial Updated:
05/30/2024
Locations: Northwestern Medicine Chicago Proton Center, Warrenville, Illinois
Conditions: Neoplasms
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Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy
NCT00969111
Recruiting
The purpose of this study is to see what effects, good and/or bad, proton radiation, and/or conventional radiation and hormonal therapy (if applicable), has on prostate cancer that has already returned or the risk of prostate cancer returning.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
05/30/2024
Locations: Northwestern Medicine Chicago Proton Center, Warrenville, Illinois
Conditions: Prostate Cancer
Register for Updates
Elements Vital to Treat Obesity Study
NCT04708769
Recruiting
The overall objective of this study is to evaluate the first rigorously optimized, remotely delivered treatment for obesity against the current gold standard treatment in a head-to-head randomized controlled trial. The investigators will be comparing the previously developed and optimized behavioral weight loss intervention (APP) to the Diabetes Prevention Program (DPP), to evaluate program weight-loss success and cost-effectiveness.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/29/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Obesity
Register for Updates
Biology and Benefits of Music Play and Stories for Kids/Parents During ALL Treatment
NCT04400071
Recruiting
Music therapy has become a standard palliative care service in many pediatric and adult hospitals; however, a majority of music therapy research has focused on the use of music to improve psychosocial dimensions of health, without considering biological dimensions. This study builds on prior work examining the psychosocial mechanisms of action underlying an Active Music Engagement (AME) intervention, designed to help manage emotional distress and improve positive health outcomes in young childre... Read More
Gender:
ALL
Ages:
Between 3 years and 8 years
Trial Updated:
05/29/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Acute Lymphoblastic Leukemia, Pediatric, Pediatric Cancer
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Understanding How Powered Componentry Impacts K2-Level Transfemoral Amputee Gait
NCT06433648
Recruiting
The goal of this study is to understand how providing power at the knee or ankle individually, or providing power at both the knee and ankle, impacts ambulation for K2 level transfemoral amputees. Aim 1: measure functional performance of K2 level ambulators when using a commercially available passive microprocessor knee prosthesis (Ottobock Cleg/Ottobock foot) or a powered knee and ankle prosthesis (SRALab Hybrid Knee and SRAlab Polycentric Powered Ankle. Aim 2: Participants will be evaluated... Read More
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
05/28/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Amputation, Amputation, Traumatic, Amputation of Knee, Amputation; Traumatic, Limb
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Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion
NCT06123026
Recruiting
The goal of this clinical trial is to compare breast symptoms (lactation, engorgement, etc) of individuals who undergo a procedure for second trimester of pregnancy loss between 16 weeks and 20 weeks gestational age. The participants will be randomly placed in two groups, one with a placebo tablet and one with medication called "cabergoline" which are taken immediately after their procedure. Researchers will compare groups to see if there are any significant differences in breast symptoms.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
05/28/2024
Locations: Northwestern Medical Center, Chicago, Illinois
Conditions: Lactation Suppressed, Second Trimester Abortion
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Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials
NCT05886764
Recruiting
This trial will study different outreach methods to assess impact on enrollment of underrepresented minorities (specifically African Americans) to early phase cancer clinical treatment trials. Both patients and providers (those seeing enrolled patients) will be enrolled and receive the study interventions or no intervention (control arm).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: University of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois
Conditions: Cancer, Malignancy, Malignant Neoplasm
Register for Updates