Illinois is currently home to 2669 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-2)
NCT06456567
Recruiting
The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of moderately to severely active SLE.
Gender:
ALL
Ages:
Between 12 years and 70 years
Trial Updated:
09/13/2024
Locations: Rockford site, Rockford, Illinois
Conditions: Systemic Lupus Erythematosus
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Evaluation of a Smartphone-based Screening Tool (Picterus JP) for Neonatal Jaundice (Chicago)
NCT05521607
Recruiting
A cross-sectional conductive study at the University of Chicago Medicine facilities (hospital and outreach clinics) to enable high qualitative estimation of bilirubin levels in the blood of newborns, independent of skin color, using Picterus JP.
Gender:
ALL
Ages:
Between 1 day and 14 days
Trial Updated:
09/13/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Neonatal Jaundice
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DNA Methylation and Vascular Function
NCT03527420
Recruiting
The main objective is to examine DNA hypomethylation as an underlying mechanism for the increased production of inflammatory cytokines and the impaired vascular function in obese individuals and as a potential target for nonpharmacological preventive/therapeutic interventions such as aerobic exercise.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
09/13/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Obesity, Vascular Dysfunction
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Single-Sided Deafness and Asymmetric Hearing Loss
NCT04506853
Recruiting
The purpose of the study is to evaluate the long-term safety and effectiveness of cochlear implantation of the approved population in adults and children with single-sided deafness and asymmetric hearing loss.
Gender:
ALL
Ages:
5 years and above
Trial Updated:
09/12/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Hearing Loss, Unilateral, Hearing Loss, Sensorineural
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Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population
NCT06538584
Recruiting
Dexmedetomidine (Dex), a selective α2-adrenergic receptor agonist, is the most used sedative for procedural sedation in children and in pediatric Intensive Care Unit (PICU) because it is associated with less respiratory depression and also less neurotoxicity; rather Dex appears neuroprotective. Unfortunately, Dex is associated with very long emergence times and may cause bradycardia and hypotension. However, using sedation dosing guidelines (by consensus among SPS members) 1-3 mcg/kg bolus and a... Read More
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
09/11/2024
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Enhanced Recovery After Surgery in a Pediatric Population
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Quantitative Assessment of Autologous Fat Transfer
NCT06343831
Recruiting
This is a single-arm, prospective pilot study that will objectively assess outcomes in patients electively undergoing Autologous Fat Transfer (AFT) for breast or chest wall reconstruction. Patients planning to undergo autologous fat transfer for breast or chest wall reconstruction will be enrolled prospectively. Participants will undergo standard photographs (2-D imaging) of their chest wall and torso, including the breasts, and complete a validated questionnaire (BREAST-QTM) to evaluate patient... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/11/2024
Locations: The University of Chicago, Chicago, Illinois
Conditions: Autologous Fat Grafting
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Effectiveness of Remote Foot Temperature Monitoring
NCT05728411
Recruiting
Diabetic foot ulcers are common, debilitating, and costly complications of diabetes, disproportionately impacting Black and rural Veterans. Forty percent of individuals have an ulcer recurrence within a year of ulcer healing and 65% within 5 years. Monitoring plantar foot temperatures is one of the few interventions that reduces the risk of ulcer recurrence. Despite the evidence, adoption has been poor because the original procedures, including the use of handheld thermometers, were burdensome a... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
09/11/2024
Locations: Edward Hines Jr. VA Hospital, Hines, IL, Hines, Illinois
Conditions: Diabetic Foot
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HF Patients With LVADs Being Treated With SGLT2i
NCT05278962
Recruiting
The main purpose of this study is to observe outcomes of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in heart failure (HF) patients with left ventricular assist devices (LVAD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/11/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Heart Failure With Reduced Ejection Fraction
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ENhancing Exercise with LIGHT to Improve Functioning in PAD
NCT06399900
Recruiting
The ENLIGHTEN PAD Trial will collect preliminary data to test whether daily 660 nm light treatment of the lower extremities immediately before home-based walking exercise sessions improves six-minute walk distance at 4-month follow-up, compared to sham light, in people with lower extremity peripheral artery disease (PAD).
Gender:
ALL
Ages:
50 years and above
Trial Updated:
09/10/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
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SMART Exercise for PAD
NCT06032065
Recruiting
Supervised exercise therapy (SET), consisting of treadmill exercise conducted three times weekly at a center while supervised by healthcare personnel, is first line therapy for people disabled by lower extremity peripheral artery disease (PAD). However, travelling three times/week to a center for SET is burdensome. Compared to SET, home-based exercise is more accessible and less burdensome. Yet, evidence-based guidelines recommend SET over home-based exercise for PAD. Walking exercise is first l... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
09/10/2024
Locations: Northwestern University Feinberg School of Medicine, Chicago, Illinois
Conditions: Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
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A Phase 2 Open Label Study of BA3021 in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT05271604
Recruiting
This is a multi-center, open-label Phase 2 study designed to evaluate the efficacy and safety of BA3021 as monotherapy and combination therapy in patients with recurrent or metastatic squamous cell carcinoma of the head and neck.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/10/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Head and Neck Cancer, Squamous Cell Carcinoma of Head and Neck, Recurrent Squamous Cell Carcinoma of the Head and Neck, Metastatic Cancer, Metastatic Squamous Cell Carcinoma of the Head and Neck
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TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers
NCT05108870
Recruiting
Doctors leading this study hope to learn about the safety and effectiveness of combining medications HB-201 and HB-202 (also known as TheraT® vectors) with chemotherapy using carboplatin and paclitaxel in the beginning of the study (induction) and if combining these medications can increase tumor shrinkage after therapy and reduce the amount of radiotherapy and chemotherapy that will later be needed. In addition, the study is looking at ways to reduce side effects overall using robotic surgery,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/10/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Human Papilloma Virus, HPV, HPV Positive Oropharyngeal Squamous Cell Carcinoma, Head and Neck Cancer
Register for Updates