Illinois is currently home to 2636 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Phase I Study of RiMO-401 With Radiation in Advanced Tumors
NCT06182579
Recruiting
This is a single arm study of RiMO-401 with radiation in patients with advanced tumors. A single escalation dose of RiMO-401 is intratumorally injected in a 3+3 study design to identify the recommended dose.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Advanced Solid Tumor, Intratumoral Injection
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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
NCT05442567
Recruiting
The study is an extension of two parent studies (MLN0002-3024 \[NCT04779307\] and MLN0002-3025 \[NCT04779320\]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
03/05/2024
Locations: Advocate Children's Hospital Park Ridge, Park Ridge, Illinois
Conditions: Ulcerative Colitis, Crohn's Disease
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Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery
NCT04885244
Recruiting
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Rush University, Department of Neurosurgery, Chicago, Illinois
Conditions: Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
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Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0
NCT04194996
Recruiting
Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Rush University, Department of Neurosurgery, Chicago, Illinois
Conditions: Cervical Deformity
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Safety and Feasibility of the ELIOS System in POAG Patients
NCT05999006
Recruiting
Evaluation of the safety and effectiveness of the ELIOS System procedure to reduce intraocular pressure (IOP) in adult subjects with mild to moderate primary open-angle glaucoma (POAG)
Gender:
ALL
Ages:
45 years and above
Trial Updated:
03/02/2024
Locations: Elios Vision Clinical Site, Rock Island, Illinois
Conditions: Glaucoma, Primary Open Angle
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Corticospinal Function After Spinal Cord Injury
NCT02451683
Recruiting
The investigator's overall goal is to develop new strategies to test optimization of Spike-timing-dependent plasticity (STDP) doses to maximize strategy to restore upper and lower-limb motor function in individuals with spinal cord injury (SCI). The investigator proposes to use modern electrophysiological methods to enhance the efficacy of residual corticospinal connections. Defining the neural basis by which corticospinal volleys generate muscle responses will provide crucial information requir... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/01/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Spinal Cord Injury
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Dronabinol After Arthroscopic Surgery
NCT05335252
Recruiting
The purpose of the proposed study is to evaluate the efficacy of dronabinol for postoperative pain after arthroscopic surgery of the knee. The investigators hypothesize that dronabinol will relieve pain, reduce opioid consumption and will result in few negative side effects. If this pilot study shows promising results the investigators will expand the trial to include additional arthroscopic surgeries (hip, shoulder) and other types of orthopaedic surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Northwestern University Feinberg School of Medicine, Chicago, Illinois
Conditions: Knee Osteoarthritis, Knee Injuries, Meniscus Tear, Synovitis of Knee, Knee Ligament Injury, Chondral Injury of Left Knee, Chondral Injury of Right Knee, Loose Body Knee
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Non Inferiority Trial Investigating Surfactants Administered Via MIST
NCT06074380
Recruiting
RESEARCH DESIGN Multicenter, randomized, controlled trial. RECRUITMENT Entry criteria Preterm infants 28-35 6/7 weeks' gestation and less than 48 hours of age who have a clinical diagnosis of respiratory distress syndrome. Infants who are on NCPAP and FiO2 ≥0.30 will randomized to curosurf or infasurf via MIST. Exclusion criteria Infants will be excluded if there is a congenital anomaly or an alternative cause for respiratory distress. Babies who require emergent intubation will not be enrolle... Read More
Gender:
ALL
Ages:
48 hours and below
Trial Updated:
02/28/2024
Locations: Northshore University Healthsystem, Evanston, Illinois
Conditions: Respiratory Distress Syndrome
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Effectiveness of Relationship Education for Reducing HIV Incidence Among SGM
NCT05678556
Recruiting
The purpose of this study is to upgrade an existing relationship education and HIV prevention program. This program is designed for gay, bisexual, queer, and transgender and non-binary people who partner with cisgender men. This means the program is designed for gay, bisexual and queer men, including both cisgender and transgender men. It is also designed for transgender and non-binary people who partner with cisgender men, including both transfeminine and transmasculine people. The investigator... Read More
Gender:
ALL
Ages:
Between 16 years and 34 years
Trial Updated:
02/27/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Hiv, Chlamydia, Gonorrhea
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Contingency Management for Drug Use: Does Age Matter?
NCT05521854
Recruiting
The OVERALL AIM is to assess whether app-based incentives are effective for older adults and to quantify the associations between age and both the efficacy and take-up of app-based incentives. This will allow us to determine if older adults with substance use disorders (SUDs) are willing to engage with app-based incentives and whether they perform similarly to their younger counterparts. Because the study will leverage data from an existing study on app-based incentives, a small add-on study is... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Advocate Health Care, Chicago, Illinois
Conditions: Opioid Use Disorder, Methamphetamine Abuse, Cocaine Use Disorder
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Chronic Pain in Rheumatoid Arthritis
NCT05038553
Recruiting
The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Arthritis, Rheumatoid, Pain
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Food Cravings Strategies During Dietary Weight Loss
NCT06280339
Recruiting
The purpose is to optimize the EMPOWER program by integrating strategies to reduce food cravings, a critical yet often overlooked factor for long-term success in weight management. The objective of this study is to determine the efficacy of craving coping strategies on weight loss outcomes by conducting a randomized controlled trial. Participants will be randomized to receive one of the two strategies to manage food cravings.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/26/2024
Locations: Bevier HAll UIUC, Urbana, Illinois
Conditions: Obesity, Food Cravings, Weight Loss
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