Illinois is currently home to 2636 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Testing "SupporT for ADHD and Related Treatment" (START) for Families of Children With ADHD
NCT05796427
Recruiting
The randomized control trial (RCT) study includes 2 aims; one being to test whether START increases access to treatment for ADHD. Investigators believe the intervention group will demonstrate improved treatment engagement and access to all treatments compared to controls. The second aim is to explore whether START leads to functional improvements across home, social and academic domains for the child and family. Investigators believe the intervention group will show better functioning including... Read More
Gender:
ALL
Ages:
Between 6 years and 12 years
Trial Updated:
02/26/2024
Locations: Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois
Conditions: ADHD
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Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
NCT01574053
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Huntington's Disease
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SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD)
NCT05701098
Recruiting
The goal of this clinical trial is to test the Break Wave™ system in patients with upper urinary tract stones. The main question it aims to answer is whether the device is safe and effective in fragmenting (breaking) stones. Participants will a) undergo the Break Wave™ procedure, b) have a telehealth visit at 2 weeks, and c) return for an imaging study at approximately 10 weeks post-procedure.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Kidney Stone, Urolithiasis, Nephrolithiasis, Renal Calculi, Kidney Calculi, Nephrolith, Urinary Calculi
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Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration
NCT05657301
Recruiting
VAN-2201 is Phase I clinical trial to assess the safety and tolerability of KH631 in subjects with neovascular AMD. KH631 is gene therapy designed to deliver a protein which targets and blocks VEGF via an adeno-associated viral vector. The standard of care for patients with neovascular AMD are anti-VEGF treaments, which have demonstrated improvement in vision and reduction in fluid. A one time placement of a product which inhibits VEGF has the potential to reduce the patient burden of regular in... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
02/23/2024
Locations: Kanghong Investigative Site, Lemont, Illinois
Conditions: Age-Related Macular Degeneration
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Intra-articular Platelet-Rich Plasma Compared With Viscosupplementation in the Treatment of Knee Osteoarthritis
NCT03491761
Recruiting
This is a single-center, prospective, randomized, single-blind, comparator therapy, parallel group study for symptomatic patients diagnosed with knee osteoarthritis. The aim is to demonstrate superior efficacy of platelet-rich plasma (PRP) as compared to hyaluronic acid (HA) in treating knee osteoarthritis. This aim will be objectively measured by endpoint consisting of changes in cartilage thickness from baseline in the MRI. The Knee Injury and Osteoarthritis Outcome Score (KOOS) Questionnaire... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/23/2024
Locations: NorthShore University HealthSystems, Skokie, Illinois
Conditions: Knee Osteoarthritis
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Cardiogenic Shock Working Group Registry
NCT04682483
Recruiting
The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Cardiogenic Shock
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Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration
NCT05643118
Recruiting
This is a Phase 1, multicenter, open-label, single- and multi-dose, dose-escalating study of OLX10212 in patients with neovascular age-related macular degeneration (AMD). This study is composed of 2 parts: Part A and Part B. Part A is a single ascending dose study, and Part B is a multiple ascending dose study. The primary objective is to evaluate the safety and tolerability of single and multiple intravitreal injection(s) of OLX10212 in patients with neovascular AMD. The exploratory objectives... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
02/20/2024
Locations: University Retina, Oak Forest, Illinois
Conditions: Neovascular Age-related Macular Degeneration
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Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal
NCT04477330
Recruiting
Achieving functional ambulation post stroke continues to be a challenge for stroke survivors, clinicians, and researchers. In the effort to enhance outcomes of motor training, cortical priming using brain stimulation has emerged as a promising adjuvant to conventional rehabilitation. This project focuses on the development of a long term gait rehabilitation protocol using brain stimulation to improve walking outcomes in people with stroke. The project will also aim to understand the neural mecha... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2024
Locations: Physical Therapy, Chicago, Illinois
Conditions: Stroke
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A Randomized Controlled Trial of Geriatric Emergency Department Innovations
NCT04115371
Recruiting
This study evaluates the Geriatric Emergency Department Innovations (GEDI) program at Northwestern Memorial Hospital to care for older adults in the emergency department. Half of the patients will be cared for by a standard ED team plus the GEDI team, while half of the patients will receive usual ED care.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
02/20/2024
Locations: Northwestern University Department of Emergency Medicine, Chicago, Illinois
Conditions: Frailty
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Prophylactic Minimally Invasive Surfactant Evaluation
NCT06007547
Recruiting
The purpose of this study is to explore the question: Does prophylactic administration of exogenous surfactant in the delivery room, using a minimally-invasive technique, improve outcome in preterm infants 22-29 weeks' gestation compared to rescue treatment using the same technique?
Gender:
ALL
Ages:
15 minutes and below
Trial Updated:
02/19/2024
Locations: Northshore University Healthsystem, Evanston, Illinois
Conditions: Respiratory Distress Syndrome, Newborn, Premature Birth
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Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia
NCT05953428
Recruiting
This is a prospective randomized, double-blinded, controlled trial that will enroll 75 subjects undergoing laparoscopic hiatal hernia repair surgery. Participants who meet eligibility criteria will be randomized in a 1:1 ratio to receive either the opioid sparring anesthesia protocol (OSA) or the opioid based anesthesia protocol (OBA). The purpose of this study is to investigate if an opioid sparring protocol for laparoscopic hiatal hernia repair will reduce opioid consumption during discharge.... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
02/19/2024
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: Hiatal Hernia
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VivAer: A Correlation Between Symptom Scores and Objective Findings
NCT05573919
Recruiting
This is a prospective, single-center study. This study seeks to determine the objective improvement in nasal airflow in patients after undergoing the VivAer procedure, which involves the use of a stylus to deliver controlled and targeted low energy radiofrequency heating (heating by applying high-frequency radio waves) to the nasal sidewall to gently reshape the tissues. Patients who experience refractory, or medically unexplained, nasal obstruction often have symptoms that are not alleviated or... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2024
Locations: Swedish Covenant Hospital, Chicago, Illinois
Conditions: Nasal Obstruction, Medically Unexplained Symptoms, Airway Obstruction, Airway Remodeling
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