Illinois is currently home to 2636 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
STAT: Standard Therapy Plus Active Therapy
NCT04368117
Recruiting
The objective of the study is to assess the efficacy of STAT, an activity-based therapy protocol compared to standard therapy (ST) to improve functional outcome and reduce disability in patients recovering from burn injury. This randomized multi-center trial is designed with two parallel treatment groups: STAT and ST. Efficacy of the STAT protocol will be determined through comparison to the ST only group. It will be conducted at seven burn centers.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/31/2024
Locations: Loyola University Medical Center, Maywood, Illinois
Conditions: Burn Injury, Physical Injury, Thermal Burn
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The Acute Burn ResUscitation Multicenter Prospective Trial
NCT04356859
Recruiting
This is a prospective randomized multi-center study which will compare acute fluid resuscitation using a colloid strategy (LR + 5% Albumin) to a crystalloid strategy (LR alone), in adults with an acute burn involving at least 25% of their total body surface area.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: Loyola Medicine, Maywood, Illinois
Conditions: Burn Injury
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Study Evaluating Safety and Efficacy of UCART123v1.2 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
NCT03190278
Recruiting
Phase I, open-label, dose-escalation and dose-expansion study evaluating the safety and efficacy of Universal Chimeric Antigen Receptor T-cell (UCART) targeting the Cluster of Differentiation 123 (CD123) in patients with relapsed/refractory acute myeloid leukemia (AML). The purpose of this study is to evaluate the safety and clinical activity of Universal Chimeric Antigen Receptor T-cells targeting CD123 (UCART123v1.2) and determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/31/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
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Foundation for Sarcoidosis Research Advanced Cures Registry (FSR-SARC Registry)
NCT06234384
Recruiting
The goal of the study is to create a longitudinal study of patient reported outcomes for people living with sarcoidosis that maintains privacy. Patients report on the following: demographics, disease symptoms, diagnostic journey, provider experience, disease treatment, and burden of disease. The goal is to create a natural history of sarcoidosis, support research, and better understand the needs of the sarcoidosis community.
Gender:
ALL
Ages:
7 years and above
Trial Updated:
01/29/2024
Locations: Foundation For Sarcoidosis Research, Chicago, Illinois
Conditions: Sarcoidosis
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AnovaOS Network Powered Patient Registry
NCT05013944
Recruiting
The objective of this study is the development, implementation and management of a registry of patient data that captures clinically meaningful, real-world, data on the diagnosis, nature, course of infection, treatment(s) and outcomes in patients with complex disease globally.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Anova Enterprises, Inc., Arlington Heights, Illinois
Conditions: Infectious Disease, Neoplasms, Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89), Endocrine, Nutritional and Metabolic Diseases (E00-E89), Mental and Behavioural Disorders, Diseases of the Nervous System, Diseases of the Eye and Adnexa, Diseases of the Ear and Mastoid Process, Diseases of the Circulatory System, Diseases of the Respiratory System, Diseases of the Digestive System, Diseases of the Skin and Subcutaneous Tissue, Diseases of the Musculoskeletal System and Connective Tissue, Diseases of the Genitourinary System, Pregnancy, Childbirth and the Puerperium, Certain Conditions Originating in the Perinatal Period, Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-Q99), Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified, Injury, Poisoning and Certain Other Consequences of External Causes, External Causes of Morbidity and Mortality, Factors Influencing Health Status and Contact With Health Services
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Robotic Mechanical Coring for the Treatment of Moderate to Severe Facial Wrinkles
NCT05091788
Recruiting
This study is a prospective, up to 4 center study of the safety and efficacy of mechanical coring with skin closure of cored holes, intended for the improvement in the appearance of wrinkles of the cheeks in up to 70 subjects after two treatments.
Gender:
ALL
Ages:
Between 22 years and 75 years
Trial Updated:
01/24/2024
Locations: DeNova Research, Chicago, Illinois
Conditions: Wrinkle
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A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: NASH - Nonalcoholic Steatohepatitis
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Multimodal Haptic Feedback for Plantar Sensory Substitution
NCT06232512
Recruiting
The study will explore the use of a haptic device for sensory substitution in individuals with a movement disorder that has caused loss of plantar sensation. The haptic device consists of two components. The first element is a flexible insole with embedded pressure-sensing elements that transmit the spatial patterns of applied foot pressure over time. The second element is a haptic receiver with embedded actuators that vibrate or heat up in proportion to the transmitted pressure patterns, thus s... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/22/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Hypoesthesia
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Improving Adherence to Spinal Cord Injury Exercise Guidelines Using Smartphone Technology and E-coaching
NCT05424172
Recruiting
The goal of this research is to increase physical activity among individuals with a spinal cord injury (SCI) through a customized, interactive smartphone-based health app and e-coaching using three phases: (1) leading focus groups of potential app users and clinicians to gain information regarding health apps preferences for optimal consumer use, (2) conducting a usability study of the customized app to determine the quality and implement further changes for optimization, and (3) conducting a se... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
01/22/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Spinal Cord Injuries
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MANAGE-AF Registry -MANAGEment of Atrial Fibrillation Outcomes Registry (MANAGE-AF)
NCT05978466
Recruiting
The purpose of this research is to learn more about the normal care of patients with a new or pre-existing diagnosis of atrial fibrillation (AF). These abnormal and irregular heartbeats place patients at increased risk of developing clots in their bloodstream that could potentially lead to stroke. Normal care is designed to help prevent this from happening and to lessen or eliminate the symptoms patients may have. There are many different types of AF as well as numerous ways in which a variety o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/17/2024
Locations: CorVita Science Foundation (NFP), Chicago, Illinois
Conditions: Atrial Fibrillation
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Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes
NCT06212518
Recruiting
The primary objective of this study is to analyze smart phone-based Transdermal Optical Imaging (TOI) features to develop a model that can discern hydration status, including: 1) at various timepoints throughout a 24-hour period in healthy adults from the general population (GENPOP), and 2) before and after a team coach-led training session in athletes competing in a sport (ATHLETE). TOI data will be collected alongside standard reference measures of hydration status. In this study each subject... Read More
Gender:
ALL
Ages:
Between 14 years and 65 years
Trial Updated:
01/13/2024
Locations: PepsiCo R&D Gatorade Sports Science Institute, Chicago, Illinois
Conditions: Dehydration
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BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer
NCT06085742
Recruiting
This is a non-randomized, single arm phase 2 trial of oral CMC based on conversion of doses that would be delivered with conventional metronomic CMF chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/10/2024
Locations: University of Illinois, Chicago, Illinois
Conditions: Breast Cancer
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