Illinois is currently home to 2642 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Performance of Inherited Risk Assessment for Predicting Prostate Cancer From Prostate Biopsy
NCT05295407
Recruiting
Condition: Prostate cancer Intervention: Biopsy and inherited risk assessment
Gender:
MALE
Ages:
Between 40 years and 69 years
Trial Updated:
03/25/2024
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: Prostate Cancer
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VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain
NCT06336447
Recruiting
This study will examine the impact of virtual reality used in conjunction with sedation compared to sedation alone in patients undergoing watervcooled genicular nerve ablations for chronic knee pain. The goals of the study is to determine the relative efficacy of virtual reality as a distraction modality when used as an adjuvant to procedural sedation compared to sedation alone for procedure related pain. To assess procedural satisfaction, and 1-month pain and functional outcomes.To explore whe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2024
Locations: Northwestern Medicine Pain Center, Chicago, Illinois
Conditions: Pain, Chronic
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Impact of Virtual Reality on Anxiety in Patients Undergoing Interventional Procedures
NCT05744336
Recruiting
Periprocedural anxiety is a common problem for patients who undergo interventional pain procedures. Virtual Reality (VR) is an immersive experience that has gained acceptance in the medical field as a tool for reducing anxiety and pain for patients.Research Aim: To evaluate the effect of immersive virtual reality (VR) on periprocedural anxiety related to therapeutic cervical epidural steroid injections (ESI). The investigators hypothesize that immersive virtual reality will result in a clinica... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/21/2024
Locations: Anesthesiology Pain Medicine Center, Chicago, Illinois
Conditions: Anxiety
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Imaging of Retinochoroidal Vasculature in Patients Being Assessed for Cardiovascular Disease
NCT05082402
Recruiting
This study aims to determine whether changes in retinal vasculature seen on SS-OCTA can be correlated to degree of cardiovascular disease as measured by carotid duplex ultrasonography.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/21/2024
Locations: Northwestern University/Northwestern Medical Group, Department of Ophthalmology, Chicago, Illinois
Conditions: Cardiovascular Diseases, Retina; Change
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Metastatic Tumor Research and Outcomes Network
NCT02830451
Recruiting
The registry aims to collect patient information such as patient demographics, co-morbidities, clinical, diagnostic, and therapeutic data, as well as information on adverse events and HRQOL outcomes specific for patients with metastatic spine tumor(s).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Rush University Medical Center University Neurosurgery, Chicago, Illinois
Conditions: Metastatic Spine Tumor
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I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients
NCT04488081
Recruiting
The goal of this project is to rapidly screen promising agents, in the setting of an adaptive platform trial, for treatment of critically ill COVID-19 patients. In this phase 2 platform design, agents will be identified with a signal suggesting a big impact on reducing mortality and the need for, as well as duration, of mechanical ventilation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: COVID-19
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A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
NCT06322693
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: GSK Investigational Site, Arlington Heights, Illinois
Conditions: Neoplasms
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KIDney Injury in Times of COVID-19 (KIDCOV)
NCT04705766
Recruiting
There is an unmet need to evaluate the impact of sub-clinical/mild COVID19 disease in the outpatient setting on prevalent and incident renal injury, as this data is currently unavailable. To capture the diversity of race/ethnic risk and COVID19 related municipal shelter-in-place guidance, the investigators will enroll COVID19-negative and COVID19-positive samples balanced by race/ethnicity from 3 different states, California, Michigan, and Illinois. Study endpoints will be assayed from urine sam... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: Rush University, Chicago, Illinois
Conditions: SARS-CoV Infection, Covid19, Corona Virus Infection, Acute Kidney Injury, Kidney Injury
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Ketamine as a Supplement to Local Anesthesia for Minor Procedures
NCT06284473
Recruiting
This trial is a double-blind randomized controlled clinical trial of adults and children (ages 7 to less than 70 years). Patients who present to the ED and who undergo minor bedside procedures that require local anesthesia will be divided into two groups: The first group will be treated with 0.7 mg/kg intranasal ketamine as well as standard local anesthesia for the procedure (treatment cohort). The second group will be treated with a volume-based dose of intranasal saline solution as well as sta... Read More
Gender:
ALL
Ages:
Between 7 years and 70 years
Trial Updated:
03/13/2024
Locations: Loyola University Medical Center, Maywood, Illinois
Conditions: Pain, Procedural, Minor Laceration, Abscess
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Evaluation of the PrevisEA Device for Predicting Gastrointestinal Impairment
NCT04880473
Recruiting
PrevisEA is a noninvasive, disposable device that uses audio spectral analysis of sounds produced by the gastrointestinal tract to predict gastrointestinal impairment (GII). GII is most commonly associated with postoperative ileus (POI), but could be the result of other causes, such as early postoperative bowel obstruction. GII is defined as failure of successful early oral re-feeding in a subject undergoing major abdominal surgery. For subjects who are allowed to resume a diet during the first... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
03/11/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Gastrointestinal Complication
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LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
ALL
Ages:
All
Trial Updated:
03/11/2024
Locations: Comprehensive Cardiovascular Care, Gurnee, Illinois
Conditions: Homozygous Familial Hypercholesterolemia
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Combining Topical Imiquimod With Local Radiotherapy for Treatment of Mycosis Fungoides
NCT05838599
Recruiting
Mycosis fungoides (MF) is the most common subtype of cutaneous T cell lymphoma (MF) and presents as cutaneous patches, plaques, and tumors. Radiation therapy (RT) is a frequently pursued management option for CTCL, especially in patients with more advanced skin disease. Imiquimod stimulates a Th1 lymphocyte response with increased IL-2 and IFN-α, but also induces IFN-α, TNF-α, IL-1α, IL-6, and IL-8, thereby bridging both innate and adaptive immunity. Dosing of both radiotherapy (RT) and imiquimo... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
03/08/2024
Locations: Northwestern University Department of Dermatology, Chicago, Illinois
Conditions: Mycosis Fungoides
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