Illinois is currently home to 2642 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study
NCT05802186
Recruiting
This phase II trial tests the effectiveness and safety of artificial intelligence (AI) to determine dose recommendation during stereotactic body radiation therapy (SBRT) planning in patients with primary lung cancer or tumors that has spread from another primary site to the lung (metastatic). SBRT uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses over a shorter period and cause less damage to normal... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Lung Carcinoma, Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Lung, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8
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Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors
NCT05394103
Recruiting
Multicenter, open-label, dose-escalation, safety, tolerability, PK and pharmacodynamic study with a dose expansion at the RP2D to evaluate safety and potential antitumor activity of Q901 as a monotherapy and in combination with pembrolizumab
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Advanced Cancer, Metastatic Cancer
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Prospective SPINE Registry
NCT04176562
Recruiting
This study is a prospective, multi-center, open label registry designed to collect real-world data on performance and safety data on RTI's spine products.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Suburban Orthopaedics, Bartlett, Illinois
Conditions: Sacroiliac; Fusion, Sacroiliac, Joint Diseases, Musculoskeletal Diseases, Spinal Disease, Spinal Stenosis, Spinal Instability, Fusion of Joint, Fusion of Spine, Spinal Fusion, Spine
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Characterization of the Microbiome in Cutaneous T Cell Lymphoma
NCT03932279
Recruiting
Investigators plan to perform a pilot study that aims to characterize the microbiome of human cutaneous T cell lymphoma patients and compare this to the microbiome of age and sex matched controls.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
03/08/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Cutaneous T Cell Lymphoma
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Dietary Supplementation on Gastrointestinal Barrier Function
NCT06262880
Recruiting
The purpose of the current study is to examine the effects of a dietary supplement containing plant derived phenolics at two different dose levels on parameters of gastrointestinal (GI) health in otherwise generally healthy adults with risk factors (high BMI and waist circumference) for increased GI permeability. The primary hypothesis is that supplementation with plant derived phenolics will improve gut health compared to placebo.
Gender:
ALL
Ages:
Between 30 years and 69 years
Trial Updated:
03/06/2024
Locations: Biofortis, Addison, Illinois
Conditions: Intestinal Permeability
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Phase I Study of RiMO-401 With Radiation in Advanced Tumors
NCT06182579
Recruiting
This is a single arm study of RiMO-401 with radiation in patients with advanced tumors. A single escalation dose of RiMO-401 is intratumorally injected in a 3+3 study design to identify the recommended dose.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Advanced Solid Tumor, Intratumoral Injection
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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
NCT05442567
Recruiting
The study is an extension of two parent studies (MLN0002-3024 \[NCT04779307\] and MLN0002-3025 \[NCT04779320\]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
03/05/2024
Locations: Advocate Children's Hospital Park Ridge, Park Ridge, Illinois
Conditions: Ulcerative Colitis, Crohn's Disease
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Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery
NCT04885244
Recruiting
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Rush University, Department of Neurosurgery, Chicago, Illinois
Conditions: Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
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Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0
NCT04194996
Recruiting
Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Rush University, Department of Neurosurgery, Chicago, Illinois
Conditions: Cervical Deformity
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Corticospinal Function After Spinal Cord Injury
NCT02451683
Recruiting
The investigator's overall goal is to develop new strategies to test optimization of Spike-timing-dependent plasticity (STDP) doses to maximize strategy to restore upper and lower-limb motor function in individuals with spinal cord injury (SCI). The investigator proposes to use modern electrophysiological methods to enhance the efficacy of residual corticospinal connections. Defining the neural basis by which corticospinal volleys generate muscle responses will provide crucial information requir... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/01/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Spinal Cord Injury
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Non Inferiority Trial Investigating Surfactants Administered Via MIST
NCT06074380
Recruiting
RESEARCH DESIGN Multicenter, randomized, controlled trial. RECRUITMENT Entry criteria Preterm infants 28-35 6/7 weeks' gestation and less than 48 hours of age who have a clinical diagnosis of respiratory distress syndrome. Infants who are on NCPAP and FiO2 ≥0.30 will randomized to curosurf or infasurf via MIST. Exclusion criteria Infants will be excluded if there is a congenital anomaly or an alternative cause for respiratory distress. Babies who require emergent intubation will not be enrolle... Read More
Gender:
ALL
Ages:
48 hours and below
Trial Updated:
02/28/2024
Locations: Northshore University Healthsystem, Evanston, Illinois
Conditions: Respiratory Distress Syndrome
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Effectiveness of Relationship Education for Reducing HIV Incidence Among SGM
NCT05678556
Recruiting
The purpose of this study is to upgrade an existing relationship education and HIV prevention program. This program is designed for gay, bisexual, queer, and transgender and non-binary people who partner with cisgender men. This means the program is designed for gay, bisexual and queer men, including both cisgender and transgender men. It is also designed for transgender and non-binary people who partner with cisgender men, including both transfeminine and transmasculine people. The investigator... Read More
Gender:
ALL
Ages:
Between 16 years and 34 years
Trial Updated:
02/27/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Hiv, Chlamydia, Gonorrhea
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