Illinois is currently home to 2681 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Non-Invasive Quantification of Liver Health in NASH (N-QUAN)
NCT04054310
Recruiting
To evaluate, in patients with suspected NASH referred for liver biopsy, the diagnostic performance of CT1 at discriminating those with NAS≥4 & F≥2 from those without.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
09/07/2023
Locations: RUSH University Medical Center, Chicago, Illinois
Conditions: NASH - Nonalcoholic Steatohepatitis
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Registry of Sarcoma Patients Treated With Permanently Implantable LDR CivaSheet®
NCT04033081
Recruiting
This patient study will determine the safety and toxicity of a permanently implantable brachytherapy source - CivaSheet® - which is designed to deliver a therapeutic dose of low dose rate (LDR) radiation with polymer encased Palladium-103. CivaSheet will be implanted in sarcoma patients with disease presenting in the retroperitoneum, abdomen, pelvis and trunk.
Gender:
All
Ages:
All
Trial Updated:
09/07/2023
Locations: Rush University Cancer Center, Chicago, Illinois
Conditions: Sarcoma
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Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis
NCT05177107
Recruiting
This is a phase IIa randomized trial designed to evaluate bacteriophage therapy in patients with diabetic foot osteomyelitis.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
09/05/2023
Locations: Podiatry 1st / Gateway Clinical Trials, O'Fallon, Illinois
Conditions: Osteomyelitis, Diabetic Foot Osteomyelitis
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To Determine the Best Feeding Practice in Preterm Infants on Non-invasive Ventilation.
NCT05824377
Recruiting
To evaluate the duration to reach full feeds by comparing continuous gavage feeds versus bolus feeds in preterm infants who are on non-invasive respiratory support (RAM cannula - short binasal prongs).
Gender:
All
Ages:
All
Trial Updated:
08/29/2023
Locations: Cook County Helath, Chicago, Illinois
Conditions: Prematurity; Extreme, Feeding Patterns, Ventilator Lung; Newborn
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Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments
NCT05479006
Recruiting
Significant motor impairments occur in 80% of individuals after moderate to severe stroke and impact the body side to the lesioned hemisphere. Typical motor impairments involve loss of dexterity with highly prevalent upper limb flexion synergy. Advances in treating flexion synergy impairments have been hampered by a lack of precision rehabilitation. Previous studies suggest and support the role of cortico-reticulospinal tract (CRST) hyperexcitability in post-stroke flexion synergy. CRST hyperexc... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
08/28/2023
Locations: Carle Foundation Hospital, Urbana, Illinois
Conditions: Stroke
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Wheelchair Backs That Support the Spinal Curves
NCT05068648
Recruiting
The overall objective of this fully powered clinical trial is to investigate if using a solid backrest on a manual wheelchair (MWC) will improve postural alignment, function and wheelchair mobility, as compared with an upholstery backrest, and to explore the impact of overall back height, contour, and seat gap when using a solid backrest in individuals with spinal cord injury (SCI).
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
08/28/2023
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Spinal Cord Injuries
Register for Updates
Surgical or Medical Treatment
NCT04128995
Recruiting
This study will test the hypothesis that metabolic bariatric surgery will be more effective at providing durable glycemic control and reduce co-morbidities than intensive medical therapy in youth with type 2 diabetes.
Gender:
All
Ages:
Between 13 years and 19 years
Trial Updated:
08/28/2023
Locations: Lurie Children's Hospital, Chicago, Illinois
Conditions: Diabetes Mellitus, Type 2, Pediatric Obesity, Bariatric Surgery Candidate
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Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments
NCT04056247
Recruiting
This study will develop an algorithm of identifying patients with stage IV NSCLC and Melanoma who could benefit from cancer treatment they receive.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/25/2023
Locations: Northwest Community Healthcare, Rolling Meadows, Illinois
Conditions: Stage IV Non-small Cell Lung Cancer, Stage IV Small Cell Lung Cancer, Stage III Malignant Melanoma, Stage IV Malignant Melanoma
Register for Updates
The Anabolic Properties of a Lipid-rich Pork Matrix
NCT05876299
Recruiting
The amount and quality of skeletal muscle mass determines physical performance, but also a significant contributor to metabolic health. As such, the maintenance of skeletal muscle mass is relevant across the lifespan to remain active in family and community life. Food ingestion, particularly protein, is one of the main anabolic to skeletal muscle tissue by stimulating muscle protein synthesis rates. There have been multiple attempts to identify specialized performance nutrition products (e.g., v... Read More
Gender:
All
Ages:
Between 20 years and 50 years
Trial Updated:
08/24/2023
Locations: Louise Freer Hall (University of Illinois Urbana-Champaign), Urbana, Illinois
Conditions: Muscle Protein Synthesis
Register for Updates
Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients
NCT05586958
Recruiting
The aim of this 6-month randomized multi-regional double-blind parallel group placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/24/2023
Locations: Healthcare Research Network II, LLC, Flossmoor, Illinois
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
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A Dose Finding Study to Treat Bone Tumor(s)
NCT06008483
Recruiting
To determine the Maximum Tolerated Dose (MTD) of CycloSam®, Samarium-153-DOTMP (Sm-153-DOTMP), a radiopharmaceutical that delivers radiation to the bone when injected, given as a tandemly administered pair of doses to subjects with one or more solid tumor(s) in the bone or metastatic solid tumors to the bone that are visible on bone scan.
Gender:
All
Ages:
Between 15 years and 75 years
Trial Updated:
08/18/2023
Locations: Clinical Trial Site, Chicago, Illinois
Conditions: Bone Cancer, Bone Tumor, Solid Tumor, Metastatic Cancer to the Bone, Metastatic Tumor to the Bone
Register for Updates
Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors
NCT02715284
Recruiting
This is a multi-center, open-label, first-in-human Phase 1 study evaluating the anti-programmed death receptor 1 (anti-PD-1) antibody dostarlimab (also known as TSR-042) n participants with advanced solid tumors who have limited available treatment options. The study will be conducted in 2 parts with Part 1 consisting of safety evaluation, pharmacokinetics (PK), and pharmacodynamics (PDy) of escalating doses of dostarlimab. Dose escalation will be based on ascending weight-based dose levels (DLs... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/18/2023
Locations: GSK Investigational Site, Chicago, Illinois
Conditions: Neoplasms
Register for Updates