Colorado is currently home to 1784 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2
Recruiting
This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinical remission in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhibitors, anti-integrin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
07/25/2024
Locations: Kaiser Foundation Research Institute, a Division of Kaiser Permanente Hospitals, Aurora, Colorado
Conditions: Ulcerative Colitis
Intervention to Educate and Improve Underrepresented Populations' Participation in Clinical Trials
Recruiting
This proposal aims to leverage ongoing community outreach efforts and the Cancer Center's aims to improve recruitment to clinical trials by educating the catchment and making referrals to engage current UCCC patients not taking advantage of available CTs at this institution and affiliated hospitals. The Cancer Prevention and Control Program within UCCC works to develop and evaluate novel approaches to primary prevention, disseminate preventative interventions in population-based settings, and to... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Cancer
Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis
Recruiting
The objectives of this multicenter pragmatic clinical trial are to compare the effectiveness and relative safety of balanced fluid resuscitation versus 0.9% "normal" saline in children with septic shock, including whether balanced fluid resuscitation can reduce progression of kidney injury.
Gender:
ALL
Ages:
Between 2 months and 17 years
Trial Updated:
07/25/2024
Locations: Children's Colorado: University of Colorado, Denver, Colorado
Conditions: Shock, Septic
Breast Cancer Patient Engagement With Patient Reported Outcome Measure Survey
Recruiting
The purpose of this research protocol is to measure Patient Reported Outcome Measures (PROMs) in breast cancer patients. PROM results will be provided to patients and providers and the investigators will evaluate the relationship between patient engagement with PROM results and patient and clinicopathologic variables, utilization of supportive and hospital services, and patient satisfaction with patient-provider communication.
Gender:
FEMALE
Ages:
All
Trial Updated:
07/25/2024
Locations: University of Colorado Hospital, Denver, Colorado
Conditions: Breast Cancer
Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
Recruiting
This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting. Optional addendums 1 and 2 included in the protocol are intended to establish comparative groups and focused subgroups within the registry.
Gender:
ALL
Ages:
All
Trial Updated:
07/25/2024
Locations: Sensation-NOW: University of Colorado School of Medicine, Aurora, Colorado
Conditions: Peripheral Nerve Injuries
Relationships Between Physical Activity and Different Measures of Fatigue in Cancer Survivors
Recruiting
This is an investigation of possible relationships between daily physical activity (PA) and different measurements of fatigue in cancer survivors participating in a cancer exercise program.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: University of Colorado Cancer Center, Aurora, Colorado
Conditions: Cancer Remission
Adjustable Continence Therapy (ACT) for the Treatment of Female SUI
Recruiting
A prospective, single arm, non-randomized, multicenter, prospective case-series trial. The purpose of this trial is to demonstrate the safety and effectiveness of using the Adjustable Continence Therapy (ACT) to provide a clinically relevant improvement in stress urinary incontinence.
Gender:
FEMALE
Ages:
22 years and above
Trial Updated:
07/22/2024
Locations: University of Colorado, Denver, Colorado
Conditions: Urinary Incontinence, Urinary Incontinence,Stress
Study to Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors
Recruiting
The objective of this study is to evaluate the safety, tolerability, and efficacy of BL-B01D1 in patients with Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/19/2024
Locations: SystImmune Recruiting Site, Boulder, Colorado
Conditions: Non Small Cell Lung Cancer, NSCLC, Lung Cancer, Breast Cancer, Esophageal Cancer, SCLC, Small Cell Lung Cancer, NPC, Nasopharyngeal Cancer
Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation
Recruiting
The "Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation" study is open to a subset of patients with disorders of sex development (DSD) which is associated with the risk of malignancy and a high risk of infertility or sterility. For these patients, experimental gonadal tissue cryopreservation is the only fertility preservation option available. The overall objective of this study is to determine the safety and efficacy of gonadal tissue cryopreservation as a method of preservin... Read More
Gender:
ALL
Ages:
30 years and below
Trial Updated:
07/18/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Ovarian Cancer
Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function
Recruiting
This study will be conducted to determine the effect of daily Tetrasol consumption in supporting gut health using assessments of gastrointestinal symptoms (GSRS) and bowel habits (BSS) as primary outcome measures. The investigators also intend to explore fecal and blood biomarkers of intestinal permeability/function, determination of anxiety and stress levels through both validated assessments and saliva and blood biomarkers, establishment of intervention safety and tolerability through comprehe... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/18/2024
Locations: Food and Nutrition Clinical Research Lab(FNCRL), Colorado State University, Fort Collins, Colorado
Conditions: Gastrointestinal Problem, Anxiety, Stress, Gastrointestinal Symptoms
MYLUNG Consortium Part 3: Observational Study
Recruiting
This longitudinal study looks to quantify the testing timeline, operational barriers, and outcomes of biomarker-guided therapy in a large, community-based, and largely unselected patient population with early stage and advanced stage, treatment-naive non-small cell lung cancer, whether squamous or non-squamous.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2024
Locations: Rocky Mountain Cancer Center, Denver, Colorado
Conditions: Carcinoma, Non-Small-Cell Lung
A Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship
Recruiting
More than 80% of childhood cancer survivors develop serious or life-threatening late effects after cancer therapy, but \<20% receive recommended survivorship care offered at cancer center survivorship clinics. In a shared care model, the investigators propose to investigate an innovative multi-level intervention consisting of: 1) patient survivorship education via telehealth with the cancer center, 2) ongoing patient-tailored education program within the electronic health record patient portal,... Read More
Gender:
ALL
Ages:
2 years and above
Trial Updated:
07/17/2024
Locations: Children's Hospital Colorado, Denver, Colorado
Conditions: Childhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, Practice, Adherence, Patient