Colorado is currently home to 1810 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry
NCT04496687
Recruiting
The aim of "iSCAD," the International Spontaneous Coronary Artery Dissection (SCAD) Registry, is to serve as an internationally collaborative, multicenter registry coordinated by an experienced and centralized coordinating center in an effort to increase the pace of participant recruitment, and thereby increase statistical power of studies related to SCAD. The ultimate goal of iSCAD Registry is to facilitate the development of best practices and clinical guidelines for preventing SCAD or its re... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/12/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Spontaneous Coronary Artery Dissection
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ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)
NCT05388708
Recruiting
ASCEND researchers are partnering with families of children who receive extracorporeal membrane oxygenation (ECMO) after a sudden failure of breathing named pediatric acute respiratory distress syndrome (PARDS). ECMO is a life support technology that uses an artificial lung outside of the body to do the lung's work. ASCEND has two objectives. The first objective is to learn more about children's abilities and quality of life among ECMO-supported children in the year after they leave the pediatr... Read More
Gender:
ALL
Ages:
Between 14 days and 20 years
Trial Updated:
12/11/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation
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Creative Arts Program to Reduce Burnout in Healthcare Professionals
NCT04276922
Recruiting
This study plans to learn if creative arts programs that include visual, musical, written, or physical expression can reduce symptoms of burnout syndrome, Post Traumatic Stress Disorder (PTSD), depression, and anxiety in critical care healthcare professionals. This study also explores if creative arts can enhance the connection to the purpose of work, the development of adequate coping skills, while providing time to connect with peers.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
12/11/2024
Locations: University of Colorado - Anschutz Medical Campus, Aurora, Colorado
Conditions: Burn-Out Syndrome, Post-Traumatic Stress Disorder, Depression, Anxiety
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Phase 1 Study of INBRX-109 in Subjects with Locally Advanced or Metastatic Solid Tumors Including Sarcomas
NCT03715933
Recruiting
This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody targeting the human death receptor 5 (DR5).
Gender:
ALL
Ages:
Between 12 years and 85 years
Trial Updated:
12/09/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Colorectal Adenocarcinoma, Ewing Sarcoma
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Accuracy of Continuous Glucose Monitors During the Perioperative Period in Youth With Type 1 Diabetes
NCT06575842
Recruiting
This study is assessing the accuracy of continuous glucose monitors during surgical procedures requiring anesthesia.
Gender:
ALL
Ages:
Between 2 years and 26 years
Trial Updated:
12/06/2024
Locations: Barbara Davis Center, Aurora, Colorado
Conditions: Type 1 Diabetes
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Comparison of Methods in Post Operative Hip Arthroscopy Rehabilitation
NCT05165927
Recruiting
The investigators plan to investigate the efficacy of blood flow restriction (BFR) therapy in post operative rehabilitation following hip arthroscopy. BFR has shown to be great at helping the recovery process. SAGA is a well-known smart training technology company, and the investigators aim to partner with SAGA to use the BFR cuffs as the intervention method. The BFR cuff will be added to the current SOC for hip scope PT for the intervention group.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/06/2024
Locations: UCHealth Steadman Hawkins Clinic Denver, Englewood, Colorado
Conditions: Hip Injuries
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Brain Oxygen Optimization in Severe TBI, Phase 3
NCT03754114
Recruiting
BOOST3 is a randomized clinical trial to determine the comparative effectiveness of two strategies for monitoring and treating patients with traumatic brain injury (TBI) in the intensive care unit (ICU). The study will determine the safety and efficacy of a strategy guided by treatment goals based on both intracranial pressure (ICP) and brain tissue oxygen (PbtO2) as compared to a strategy guided by treatment goals based on ICP monitoring alone. Both of these alternative strategies are used in s... Read More
Gender:
ALL
Ages:
14 years and above
Trial Updated:
12/06/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Brain Injuries, Traumatic
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ET1 Concentration, Metabolic Pathway Activation, and Pulmonary Blood Flow in Infants Undergoing Superior Cavo-Pulmonary Anastomosis
NCT03404258
Recruiting
This is a novel preliminary study of biomarkers of pathologic pre-operative pulmonary vascular development, elevated pre-operative Pulmonary Vascular Resistance Index (PVRi), and complications associated with decreased post-operative pulmonary blood flow in single ventricle patients undergoing superior cavo-pulmonary anastomosis (SCPA). The study will utilize a combined targeted and untargeted approach to both optimize translation of a promising existing biomarker and efficiently identify novel... Read More
Gender:
ALL
Ages:
Between 1 month and 2 years
Trial Updated:
12/06/2024
Locations: Children's Hospital Colorado, Denver, Colorado
Conditions: Single-ventricle, Pulmonary Vascular Resistance Abnormality, Superior Cavo-Pulmonary Anastomosis, Endothelin, Metabolomics
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The Immune System's Response to Young Women's Breast Cancer
NCT01503190
Recruiting
This study plans to learn more about the immune system's response to breast cancer in young women.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/06/2024
Locations: University of Colorado Denver, Aurora, Colorado
Conditions: Breast Cancer, Breast Cancer and Pregnancy
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Assessment of Safety of the Use of Fenfluramine in Children With Dravet Syndrome Under 24 Months of Age
NCT06598449
Recruiting
Dravet syndrome is a genetic epilepsy associated with pathogenic variants in SCN1A that codes for Nav1.1, a protein necessary for sodium channels. Children with Dravet syndrome classically present in the first year of life with prolonged seizures, often hemiclonic and in the setting of fever or temperature changes such as getting in or out of bath water. Many anti-seizure medications are sodium channel blockers and exacerbate seizures in this patient population. This creates some limitations in... Read More
Gender:
ALL
Ages:
Between 12 months and 24 months
Trial Updated:
12/05/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Dravet Syndrome (DS), Children Under 2 Years
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Using Simplified Meal Boluses Versus Carbohydrate Counting in Adolescents With Hybrid Closed Loop Systems
NCT06575790
Recruiting
The goal of this trial is to evaluate blood sugar control in patients with type 1 diabetes when using a simple meal bolus strategy (small, medium, large meals) compared to carbohydrate counting when on a hybrid closed loop system. The main question it aims to answer are: What is the blood sugar time in range when using simple meal boluses versus carbohydrate counting? Participants will: Use the simple meal bolus plan for 4 weeks. Do precise carbohydrate counting for 4 weeks. Provide their con... Read More
Gender:
ALL
Ages:
Between 14 years and 26 years
Trial Updated:
12/05/2024
Locations: Barbara Davis Center, Aurora, Colorado
Conditions: Type 1 Diabetes
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Vafseo Outcomes In-Center Experience
NCT06520826
Recruiting
This trial is an investigator-initiated, multi-center, randomized (1:1), open-label, active-controlled, pragmatic study of the safety of vadadustat administered three times per week for the treatment of anemia in in-center hemodialysis patients with End Stage Kidney Disease (ESKD). This study will obtain long-term safety data in a large sample of subjects receiving in-center hemodialysis to support adoption of three times per week vadadustat dosing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: USRC Kidney Research, Lone Tree, Colorado
Conditions: Anemia of Chronic Kidney Disease
Register for Updates