Colorado is currently home to 1810 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Safety and Efficacy of Radio Frequency for the Treatment of Mild to Severe Inflammatory Acne
NCT05830968
Recruiting
The aim of this trial is to evaluate the safety and efficacy of the InMode RF Pro System with the Morpheus8 face tip (24 pins) applicator for the treatment of mild, moderate and severe, facial acne vulgaris
Gender:
ALL
Ages:
16 years and above
Trial Updated:
05/28/2024
Locations: AboutSkin Research, LLC, Greenwood Village, Colorado
Conditions: Inflammatory Acne Vulgaris
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Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
ALL
Ages:
All
Trial Updated:
05/24/2024
Locations: Colorado Neurodiagnostics, Littleton, Colorado
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
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Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults (TANDEM Study)
NCT06311487
Recruiting
This study plans to learn more about metabolic responses to aerobic exercise at different times of the day (morning or evening) under fasting versus fed conditions.
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
05/22/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Overweight and Obesity, Healthy
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Swelling Management After Knee Replacement
NCT06095401
Recruiting
To determine if inelastic adjustable compression garment results in improved surgical limb swelling control (bioimpedance assessment - primary outcome) after TKA compared to control (TED hose).
Gender:
ALL
Ages:
Between 50 years and 120 years
Trial Updated:
05/22/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Arthroplasties, Knee Replacement
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Decision Aid for Parents of Infants With UPJO
NCT05900375
Recruiting
Ureteropelvic junction obstruction (UPJO) is the most common etiology of high-grade hydronephrosis, affecting approximately 4,000-10,000 infants annually in the U.S. The goal of surgical treatment of UPJO is to minimize the risk of kidney damage associated with obstruction, which may occur in 30-60% of infants with high-grade hydronephrosis.1-However, the benefit of early surgery compared to observation and potential later surgery to preserve kidney function has not been well-defined. Consequent... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/22/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Ureteropelvic Junction Obstruction, Ureteropelvic Junction; Obstruction, Congenital
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Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure
NCT04160000
Recruiting
Heart failure (HF) with preserved left ventricular function (pEF) is difficult clinical syndrome to treat effectively with few evidence based therapies. Atrial fibrillation (AF) is now an important co-morbidity being observed in 43% of patients with HFpEF. Rhythm control has not been studied in this population. Catheter ablation and antiarrhythmic drugs are rhythm control therapies that have been used for treatment of AF without HF or HF with reduced systolic function but have not been widely ap... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/22/2024
Locations: South Denver Cardiology, Littleton, Colorado
Conditions: Atrial Fibrillation, Heart Failure, Diastolic Heart Failure
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Treatment of Exercise-Induced Pulmonary Vascular Dysfunction After Pulmonary Thromboendarterectomy or Balloon Pulmonary Angioplasty
NCT03409588
Recruiting
This is an open label study of Riociguat in patients with continued exercise intolerance at least 6 months following pulmonary endarterectomy (PEA).
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/22/2024
Locations: University of Colorado, Anschutz Medical Campus, Aurora, Colorado
Conditions: Chronic Thromboembolic Disease (CTED), Exercise Intolerance Post PEA Surgery
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Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block
NCT04559425
Recruiting
Few studies are specifically designed to address health concerns that are already relevant during pregnancy. The consequence is a lack of evidence on best clinical practice. This includes mothers and their babies when pregnancy is complicated by an abnormally slow heart rate due to maternal antibody-mediated heart disease in the unborn baby (fetus). Since the late seventies, it has been possible to detect and monitor fetal disease by ultrasound images and to treat selected conditions with pharma... Read More
Gender:
FEMALE
Ages:
Between 16 years and 50 years
Trial Updated:
05/21/2024
Locations: Children's Hospital Colorado, Denver, Colorado
Conditions: Heart Block Complete, Heart Block Second Degree
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Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies
NCT04404101
Recruiting
Pancreatic cystic lesions (PCLs) are a common incidental finding in cross sectional imaging (up to 27% on CT scan and 41% on MRI) and pose a management challenge to physicians. According to society guidelines, PCLs with specific features should prompt additional workup with endoscopic ultrasound (EUS) for cyst characterization as well as cyst sampling. This can help determine if the cyst is mucinous or non-mucinous which has implications for its malignant potential. Cyst fluid has traditionally... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/20/2024
Locations: University of Colorado - Anschutz Medical Campus, Aurora, Colorado
Conditions: Pancreatic Cyst
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Prospective Evaluation of the Efficacy and Safety of Endoscopic Tissue Apposition
NCT03626194
Recruiting
This study is a prospective registry of patients undergoing endoscopic suturing and/or clip placement at our institution to assess the efficacy and safety of endoscopic tissue apposition. 1.1 Hypothesis: Endoscopic tissue apposition is efficacious and safe in the practice of gastrointestinal endoscopy. 1.2 Aims: To prospectively evaluate the efficacy and safety of Endoscopic Tissue Apposition in the practice of gastrointestinal endoscopy.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/20/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Endoscopic Tissue Apposition, Endoscopic Suturing, Endoscopic Clipping, Bariatric Endoscopy, Transoral Outlet Reduction, Endoscopic Sleeve Gastroplasty
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Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)
NCT04474223
Recruiting
Fetal complete (i.e., third degree, 3°) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally associated with maternal anti-Ro autoantibodies and results in death in a fifth of cases. To date treatment of 3° AVB has been ineffective in restoring normal rhythm (NR) which may be because current surveillance is limited to once- weekly fetal echocardiograms. It is hypothesized that there may be a vital transition p... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: University of Colorado, Denver (UCD), Aurora, Colorado
Conditions: AVB - Atrioventricular Block, Fetal AVB
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A Room Temperature Atomic Magnetrode System for Telemetry of Epileptic Seizures
NCT04515316
Recruiting
This study is being done to help scientists learn about the use of a device called an atomic magnetometer. The device uses sensors called optically-pumped magnetometers (OPM) which function at room temperature. This research will compare the non-invasive brain imaging application of the OPM sensors to the present SQUID-based cryogenic sensor technique used in conventional Magnetoencephalography (MEG). This study is being conducted in conjunction with the University of Colorado Boulder's Mechani... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
05/14/2024
Locations: University of Colorado School of Medicine - Anschutz Medical Campus, Aurora, Colorado
Conditions: Epilepsy
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