Colorado is currently home to 1804 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Cannabidiol and Older Adult Cannabis Users
NCT06290063
Recruiting
Cannabis use increased 10 fold among adults over the age of 65 between 2014 and 2016 but very little data exists on the extent of their harmful effects on health and behavior. The overarching goal of this project is to test a novel harm reduction strategy in which older individuals who seek to use cannabis for pain, anxiety or mood problems (depression/anxiety) will be randomly assigned to one of three conditions in an 8 week randomized controlled trial: hemp-derived CBD+THC, hemp-derived CBD-TH... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/06/2024
Locations: University of Colorado at Boulder, Boulder, Colorado
Conditions: Sleep, Anxiety, Depression, Pain
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Levonorgestrel 52 mg IUD for Emergency Contraception and Same-Day Start
NCT05444582
Recruiting
This is a prospective clinical research study to test the effectiveness of the Levonorgestrel (LNG) 52 mg Intrauterine Device (IUD) for emergency contraception (EC) and same-day start use that will enroll people receiving care at Planned Parenthood affiliates across the U.S. Our prior work demonstrated efficacy (shows that it works in an ideal setting) for the LNG 52 mg IUD for these uses and this study will test effectiveness (how well it works in the real world) in a larger, heterogenous popul... Read More
Gender:
FEMALE
Ages:
Between 16 years and 35 years
Trial Updated:
05/06/2024
Locations: Planned Parenthood of the Rocky Mountains, Denver, Colorado
Conditions: Contraception
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WayToServePlus: Improving Responsible Alcohol Service Ph II
NCT05779774
Recruiting
Responsible beverage service (RBS) training for alcohol servers is a promising intervention for reducing driving while intoxicated (DWI) by alcohol. Training, certification, and in-service contact improves professionalism and effectiveness of prevention interventions delivered by community members such as alcohol servers. This SBIR Fast-track project will develop and test an in-service professional development component to the WayToServe® online RBS training to improve the effectiveness of RBS t... Read More
Gender:
ALL
Ages:
19 years and above
Trial Updated:
05/02/2024
Locations: Klein Buendel, Inc, Golden, Colorado
Conditions: Alcohol Drinking, Alcohol Intoxication, Alcohol Use, Unspecified
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A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
NCT06399393
Recruiting
The purpose of this study is to compare the efficacy, safety, and tolerability of ide-cel with lenalidomide (LEN) maintenance to that of LEN maintenance alone in adult participants with Newly Diagnosed Multiple Myeloma (NDMM) who have achieved a suboptimal response post autologous stem cell transplantation (ASCT).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Colorado Blood Cancer Institute, Denver, Colorado
Conditions: Multiple Myeloma
Register for Updates
1a/1b Study of OPT101 First in Human Study Assessing Safety and Tolerability of 15-mer Peptide.
NCT04589403
Recruiting
This is a first-in-human study, Phase 1, randomized, placebo-controlled, double blinded study that will be conducted in 2 parts.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
05/01/2024
Locations: IMMUNOe Research, Centennial, Colorado
Conditions: Healthy
Register for Updates
Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease
NCT06397677
Recruiting
A study to identify patients with Rheumatoid Arthritis - Associated Interstitial Lung Disease (RA-ILD) that are at the highest risk for progression. The goal of the investigators is to recruit a group of patients with RA-ILD and collect information to help us understand more about disease progression. The investigators will do this using a combination of clinical, radiologic, and biologic features.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/29/2024
Locations: University of Colorado Denver, Aurora, Colorado
Conditions: Rheumatoid Arthritis, Interstitial Lung Disease
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THRIVE Study: Positive Affect Training for Endocrine Therapy Medication Adherence
NCT06388304
Recruiting
The purpose of this study is to pilot and refine an online behavioral intervention based on Positive Affect Training (PAT) that aims to increase positive emotional attitudes and decrease negative emotional attitudes toward endocrine therapy (ET, i.e., anti-hormonal medication) and to increase positive affect and decrease negative affect more generally, among post-treatment breast cancer survivors who are prescribed ET to prevent recurrence of breast cancer.
Gender:
FEMALE
Ages:
21 years and above
Trial Updated:
04/24/2024
Locations: University of Colorado Boulder, Boulder, Colorado
Conditions: Breast Cancer, DCIS
Register for Updates
The Effect of Adipose-Derived Stem Cells for Knee Osteoarthritis
NCT03014401
Recruiting
The purpose of this study is to compare the clinical and functional outcomes of patients with mild to moderate arthroscopically confirmed osteoarthritis between the following two groups: 1. Partial fat pad harvest with Adipose-Derived Stem Cell (ADSC) transplantation with standard arthroscopic treatment consisting of: partial meniscectomy, cartilage stabilization, loose body removal and selective synovectomy. 2. Standard arthroscopic treatment (above) without cell transplant.
Gender:
ALL
Ages:
Between 35 years and 70 years
Trial Updated:
04/24/2024
Locations: UC Health Steadman Hawkins Clinic - Denver Inverness, Denver, Colorado
Conditions: Knee Osteoarthritis
Register for Updates
Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects
NCT02090140
Recruiting
The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the subchondral bone marrow to the site of cartilage loss. The second method is the application of adipose-derived stem cells (ADSCs) to the defect site. In theory, ADSCs on a collagen scaffold should enable the delivery of more specific progenitor cells to the site of injury... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
04/24/2024
Locations: UC Health Steadman Hawkins Clinic - Denver Inverness, Denver, Colorado
Conditions: Degenerative Lesion of Articular Cartilage of Knee
Register for Updates
Ultrasound Investigation Into Swimming Induced Pulmonary Edema in Open Water Swimming Athletes
NCT06384885
Recruiting
Swimming-induced pulmonary edema (SIPE) is a potentially life-threatening condition that can affect swimmers of all abilities. The pathophysiology is not well understood and early identification strategies are not established. Handheld ultrasound is a validated tool for the identification of pulmonary edema and is not well-studied in this population. Understanding the incidence of signs of pulmonary edema and its usefulness as a sign of early pulmonary edema would be beneficial This study evalua... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: Rocky Vista University, Parker, Colorado
Conditions: Swimming Induced Pulmonary Edema
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Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling
NCT06129110
Recruiting
The goal of this intervention study is to learn about how weight loss impacts molecular signaling of intermuscular adipose tissue (IMAT) in individuals with obesity. The main question it aims to answer is how inflammatory molecules secreted by IMAT promote muscle insulin resistance and inflammation, and how these same molecules are diminished after weight loss. Following screening visits involving body composition measures, blood testing, strength testing, and a thigh muscle biopsy, participants... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
04/22/2024
Locations: University of Colorado Anschutz, Aurora, Colorado
Conditions: Obesity, Insulin Sensitivity, Muscle Weakness, Adiposity, Insulin Resistance
Register for Updates
Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus
NCT05056051
Recruiting
Esophageal cancer is a deadly disease that is becoming increasingly common in the United States. Barrett's esophagus (BE) is a pre-cancerous state that can develop into esophageal cancer, but is highly treatable. Progression of BE to esophageal cancer is still common due to missed diagnosis of Barrett's esophagus recurrence following treatment. Wide-Area Trans-Epithelial Sampling (WATS-3D) is a new technology that uses brush sampling to examine larger areas of the esophagus as compared to conven... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Barrett Esophagus, Esophageal Cancer
Register for Updates