Colorado is currently home to 1810 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Denver, Aurora, Colorado Springs and Englewood. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase
NCT05820919
Recruiting
This study seeks to improve clinical outcomes for an important, growing, and vulnerable population-nursing home residents with Alzheimer's disease or related dementias-by testing an evidence-based intervention to improve these residents' sleep. It will also examine the implementation and sustainment of this intervention.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
03/11/2024
Locations: Vivage/Beecan Corporation, Lakewood, Colorado
Conditions: Alzheimer Disease, Dementia, Sleep Disorder, Sleep Disturbance
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LOWER: Lomitapide Observational Worldwide Evaluation Registry
NCT02135705
Recruiting
This global product exposure registry is a multicentre, long-term, prospective, observational cohort study (exposure registry), designed to evaluate the long term safety and effectiveness of lomitapide.
Gender:
ALL
Ages:
All
Trial Updated:
03/11/2024
Locations: University of Colorado Health, Aurora, Colorado
Conditions: Homozygous Familial Hypercholesterolemia
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Mitigation of Arthrofibrosis After Total Knee Arthroplasty Using Losartan
NCT06108063
Recruiting
The purpose of this study is to evaluate the efficacy of Losartan use post-operatively for reducing or preventing the development of arthrofibrosis and the associated adverse impacts on clinical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: The Steadman Clinic, Vail, Colorado
Conditions: Knee Arthroplasty, Total
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Evaluation of Symphony™ Posterior Cervical System for Surgical Treatment of Adult Cervical Deformity
NCT04912674
Recruiting
Multi-center, prospective, non-randomized study to evaluate Symphony™ Posterior Cervical System in the setting of surgical treatment of adult cervical deformity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Denver International Spine Center, Rocky Mountain Hospital for Children and Presbyterian St. Luke's Medical Center, Denver, Colorado
Conditions: Cervical Deformity
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Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0
NCT04194996
Recruiting
Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Denver International Spine Center, Rocky Mountain Hospital for Children and Presbyterian St. Luke's Medical Center, Denver, Colorado
Conditions: Cervical Deformity
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Complex Adult Deformity Surgery (CADS)
NCT04194138
Recruiting
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Denver International Spine Center, Rocky Mountain Hospital for Children and Presbyterian St. Luke's Medical Center, Denver, Colorado
Conditions: Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
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Cerebral Hemorrhage Risk in Hereditary Hemorrhagic Telangiectasia
NCT01158807
Recruiting
This study is one of the three projects of an NIH Rare Disease Clinical Research Consortium. A "consortium" is a group of centres sharing information and resources to perform research. The consortium research focuses on brain blood vessel malformations in three different rare diseases. The focus of this specific study is on Hemorrhagic Telangiectasia (HHT). HHT is a condition characterized by blood vessel malformations, called telangiectasia and arteriovenous malformations (AVMs), occurring in... Read More
Gender:
ALL
Ages:
All
Trial Updated:
03/04/2024
Locations: UCHealth Pulmonary Vascular Disease Clinic - Anschutz Medical, Aurora, Colorado
Conditions: Hereditary Hemorrhagic Telangiectasia
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Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes
NCT06297980
Recruiting
The objectives of this study are to examine how sex hormones (use of hormonal birth control, menstrual cycle phase) impact glycemic control among women with type 1 diabetes (T1D), and to test adjustments to insulin dosing and food intake to ameliorate cycle-related glycemic variability. A secondary aim is to examine how the menstrual cycle and use of hormonal birth control impact patient-reported outcomes and glycemic responses to physical activity.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
02/29/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Type 1 Diabetes, Hypoglycemia, Hyperglycaemia Due to Type 1 Diabetes Mellitus, Menstruation Disturbances
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Biomarkers for Peripheral Circadian Clocks in Humans
NCT06296823
Recruiting
The purpose of this project is to improve our understanding of peripheral circadian rhythms in humans. Circadian clocks are present in most tissues of the body with importance for optimal physiological function, health, and behavior. This project will utilize simulated jetlag protocols to systematically test novel hypotheses about the regulation of peripheral circadian rhythms in humans. Specifically, we will examine how changes in the time of when we are exposed to light and the timing of when... Read More
Gender:
ALL
Ages:
Between 17 years and 35 years
Trial Updated:
02/29/2024
Locations: Sleep and Chronobiology Laboratory, Boulder, Colorado
Conditions: Circadian Rhythms
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5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece.
NCT06287346
Recruiting
The goal of this cohort observational study is to compare in the survival rate of ceramic dental implants placed in patients with missing or hopeless teeth . The main question\[s\] it aims to answer are: * Are there any significant differences in survival rate between the use of one-piece ceramic implant versus the two-piece (TL) variant? * What are the complications associated to the procedure and differences between the two groups.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Family Holistic Dentistry, Boulder, Colorado
Conditions: Edentulism, Tooth Loss
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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
NCT06008197
Recruiting
Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Aurora, CO Investigative Site, Aurora, Colorado
Conditions: Heart Failure, Acute Heart Failure
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A Prospective Study of a Mosaic Embryo Transfer
NCT04472156
Recruiting
This research is a prospective study in which the purpose is to investigate the clinical outcomes following the transfer of a mosaic embryo (presence of both chromosomally normal and abnormal cells) that has been screened for preimplantation genetic testing (PGT).
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
02/28/2024
Locations: Colorado Center for Reproductive Medicine, Lone Tree, Colorado
Conditions: Infertility
Register for Updates