There are currently 241 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
EvaluatIng Normal Values for TraditionaL AnorectaL FUnction ParaMeters with AIr Charged and Solid State HRAM CatheTErs ("ILLUMINATE" Study)
NCT06805240
Recruiting
The research study will be conducted to obtain baseline, or "normative" information to compare an air charged HRAM catheter to traditional solid catheter measures using the IAPWG standardized testing protocol and London classification.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
03/18/2025
Locations: Augusta University Digestive Health Center, Augusta, Georgia +2 locations
Conditions: Healthy
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Adipose Tissue Blood Flow in Aging Humans
NCT06096532
Recruiting
The goal of this basic science clinical trial is to understand whether adipose tissue blood flow changes between younger and older healthy adults. The main question\[s\] it aims to answer are: * Is basal and nutrient responsive adipose tissue blood flow (ATBF) different between younger and older adults * What molecular and systemic signatures related to adipose tissue blood flow are altered between these two groups. Participants will undergo measurements of adipose tissue blood flow using the... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/17/2025
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Healthy, Aging
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A Study to Evaluate the Impact of Lactobacillus Rhamnosus GG on Proton Pump Inhibitor-Induced Gut Dysbiosis
NCT05517928
Recruiting
The purpose of this study is to investigate the impact of the probiotic Lactobacillus rhamnosus (LGG) on proton pump inhibitor (PPI)-induced changes to the microbes that live in the gastrointestinal tract and are passed out in the stool. PPI medicines reduce stomach acid and are commonly used to treat acid reflux disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/13/2025
Locations: Mayo Clinic Arizona, Scottsdale, Arizona
Conditions: Healthy
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A Community Health Education Intervention for Increasing Community-driven Actions to Reduce the Cancer Burden in Western New York
NCT06681077
Recruiting
This clinical trial evaluates a community health education intervention (I CAN) for increasing community-driven actions to reduce the cancer burden in Western New York. Engaging community members is a critical component of designing impactful programs to reduce the cancer burden. Leaders at the national, state, and local levels have all called for more community partnerships and engagement in design of health intervention and policies. The I CAN intervention is a workshop that includes a present... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/11/2025
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Healthy
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High-resolution Phosphocreatine and Creatine Mapping of Human Muscle and Brain
NCT04234880
Recruiting
In this study, we aim to develop and validate a noninvasive approach for quantifying and imaging energy metabolism, without contrast agents, on widely available clinical MRI scanners. Briefly, this technique allows specific and selective imaging of the energy metabolite phosphocreatine (PCr), in vivo and non-invasively. PCr is one of the predominant high-energy phosphates present in brain and muscle and one that is altered by common diseases. Although energy metabolism and PCr play a vital role... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/05/2025
Locations: F. M. Kirby Center and Johns Hopkins University Medical School, Baltimore, Maryland
Conditions: Healthy
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A Study to Test the Effects of Nezavist At Different Doses in Healthy Adults
NCT06633562
Recruiting
The goal of this clinical trial is to determine the safety, tolerability and effects of Nezavist in healthy adults. The main questions it aims to answer are: * What is the safety and maximum tolerated dose (MTD) of orally administered Nezavist formulated as a spray dried dispersion (SDD) in healthy volunteers? * What are the pharmacokinetics (PK) of orally administered Nezavist SDD and its major metabolite (DCUKA) across a range of doses in healthy volunteers? Researchers will compare the acti... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
02/28/2025
Locations: The Altman Clinical and Translational Research Institute, La Jolla, California
Conditions: Healthy, Safety Evaluation of Escalating Doses, Tolerability
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Drug Discovery for Parkinson's with Mutations in the GBA Gene
NCT05536388
Recruiting
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate Parkinson's disease research and drug development by using cells from the body (such as skin or blood cells) to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and/or store the samples for future use. Through this research, researchers hope to identify future treatments or even cures for Parkinson's disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: The New York Stem Cell Foundation Research Institute, New York, New York
Conditions: Parkinson Disease, Gaucher Disease, Healthy, GBA Gene Mutation
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Observational Study of Exposure to Environmental Toxicants Among Firefighters
NCT05643014
Recruiting
Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Healthy
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Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for IPSC Generation and Biobanking
NCT06203093
Recruiting
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate Charcot-Marie-Tooth disease research and drug development by using cells from the body (such as skin or blood cells) to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and/or store the samples for future use. Through this research, researchers hope to identify future treatments or even cures for Charcot-Marie-Tooth disease.
Gender:
ALL
Ages:
5 years and above
Trial Updated:
02/27/2025
Locations: New York Stem Cell Foundation Research Institute, New York, New York
Conditions: Charcot-Marie-Tooth Disease, Healthy
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Spectral Characteristics of Memory Transformation
NCT05946616
Recruiting
Sometimes, it is necessary to re-learn a previously learned movement behavior, for example, a bad posture during the golf drive or while playing the piano. Unlearning or relearning an intensively trained behavior is particularly important if the behavior is hampering recovery, for example, in chronic pain or after a stroke. With this pilot study, the brain mechanisms that control the change of pre-existing stable memories of a motor skill will be tested with electroencephalography (EEG). Non-inv... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Healthy
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A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers
NCT06667661
Recruiting
The goal of this clinical trial is to evaluate whether a home-based mHealth intervention can improve adherence to the 24-Hour Movement Guidelines in preschool-aged children (3-4 years old) who currently meet 0 or 1 of the guidelines for physical activity, sedentary behavior, and sleep. The main questions it aims to answer are: * Can the intervention increase the proportion of children meeting all three 24-Hour Movement Guidelines (physical activity, screen-time, and sleep)? * Is the interventio... Read More
Gender:
ALL
Ages:
Between 3 years and 4 years
Trial Updated:
02/25/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Healthy, 24-Hour Movement Guidelines, Feasibility Studies, Sleep, Physical Activity, Screen Time, Sedentary Behaviors, Motor Skills, Cognition, Parent-Child Relations, Mobile Application, Health Education, Child Development
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A Study of Invasive Hemodynamic for MACHD Registry
NCT05849025
Recruiting
This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Congenital Heart Disease
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