There are currently 231 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
SV2 PET Imaging With [11C]APP311
Recruiting
The aim of this study is to evaluate a new SV2A tracer, [11C]APP311, in healthy aging and neuropsychiatric disorders including psychotic disorders and cannabis use disorders.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
02/12/2024
Locations: Conneticut Mental Health Center, New Haven, Connecticut
Conditions: Schizophrenia and Other Psychotic Disorders, Cannabis Use Disorder, Healthy
Computational Drug Repurposing for All EBS Cases
Recruiting
The study will compare gene expression differences between blistered and non-blistered skin from individuals with all subtypes of EB, as well as normal skin from non-EB subjects. State of the art computational analysis will be performed to help identify new drugs that might help all EB wound healing and reduce pain. Researchers will focus on drugs that have already been approved for treatment of other dermatologic or non-dermatologic diseases, and therefore be repurposed for treatment of EB. Dru... Read More
Gender:
All
Ages:
0 years and above
Trial Updated:
02/11/2024
Locations: Pediatric Dermatology Clinic at Stanford Children's Hospital, Palo Alto, California
Conditions: Epidermolysis Bullosa Simplex, Healthy, Genetic Skin Disease, Epidermolysis Bullosa, Epidermolysis Bullosa, Junctional, Epidermolysis Bullosa Dystrophica
Fully Automated High-Throughput Quantitative MRI of the Liver
Recruiting
The purpose of this research is to see if a new automated magnetic resonance imaging (MRI) method will be able to improve the images taken of the liver. Participants will have either known or suspected liver disease, known or suspected iron overload syndrome, or be a healthy adult. Participants will be in the research study for one day.
Gender:
All
Ages:
7 years and above
Trial Updated:
02/09/2024
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Healthy, Iron Overload, Liver Fat
Observational Study of Exposure to Environmental Toxicants Among Firefighters
Recruiting
Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/08/2024
Locations: Masonic Cancer Center, Minneapolis, Minnesota
Conditions: Healthy
Safety of Ashwagandha (Withania Somnifera) Root Extract
Recruiting
The primary objective is to evaluate the laboratory safety of Ashwagandha standardized root extract 500 mg capsules in healthy adults over 12-week therapy based on Complete Blood Count, Renal Function Test, Liver Function Test, Lipid Profile and Thyroid Function Test, Fasting blood sugar and HbA1c Test. The secondary objectives are to evaluate the clinical safety of Ashwagandha standardized root extract 500 mg capsules in healthy adults over 12-week therapy and to evaluate the effect of the Ashw... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/07/2024
Locations: SF Research Institute, San Francisco, California
Conditions: Healthy
Study of Healthy Cohort for Early Detection of Cancer
Recruiting
Cancer produces a significant burden on society with a majority diagnosed at late stages when the chance of cure is low. Early diagnosis improves patient outcomes. Data consisting of lifestyle factors, medications, physical activity, years before conventional cancer diagnosis is also worthwhile for to determine early detection. This is only achievable with longitudinal tracking of a large number of healthy individuals and identifying those who do develop cancer over time.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/07/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Healthy
Protein Requirements for Active Children
Recruiting
There is reason to believe the current dietary reference intakes for dietary protein for children are too low. Furthermore, children with high levels of physical activity and fitness may require a higher requirement. To better understand the protein requirements in minimally and highly physically fit and active children 8-10 y old, investigators will use the indicator amino acid oxidation technique.
Gender:
All
Ages:
Between 8 years and 10 years
Trial Updated:
02/01/2024
Locations: Arkansas Children's Nutrition Center, Little Rock, Arkansas
Conditions: Healthy
The Validation Study of Bioelectronics
Recruiting
The purpose of this study is to investigate the safe wearability and basic functions of the multi-modality sensors fabricated in the PI lab.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
01/31/2024
Locations: Kenan Laboratories at the University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Healthy, Health Behavior
[18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy Subjects
Recruiting
Background: Inflammation in the brain plays a role in many diseases. Being able to measure inflammation in a person s brain might help to diagnose and treat these diseases. One protein (TSPO) appears in higher numbers when inflammation affects the brain. To see TSPO when a person s body is scanned, researchers need a substance called a radiotracer that will attach to this protein and no other molecules. Objective: This study will test whether a new radiotracer ([18F]SF12051) can make TSPO app... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
01/30/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy
A Study of LY3502970 in Participants With Impaired and Normal Liver Function
Recruiting
The main purpose of this study is to measure how much of LY3502970 gets into the bloodstream and how long it takes the body to eliminate it in participants with mild, moderate and severe impaired liver function compared to participants with normal liver function. The safety and tolerability of LY3502970 will also be evaluated. The study may last up to 6 weeks for each participant including the screening period.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/29/2024
Locations: Clinical Pharmacology of Miami, Miami, Florida +3 locations
Conditions: Healthy, Hepatic Insufficiency
Genesis Electrical Impedance Tomography (EIT): A Preliminary Study
Recruiting
The purpose of this study is to evaluate the Genesis Electrical Impedance Tomography (EIT) imaging system for use in pediatric respiratory disease populations including neuromuscular and bronchopulmonary dysplasia, as well as in age and height matched controls. The EIT does not use radiation, and is read through electrodes.
Gender:
All
Ages:
Between 14 days and 40 years
Trial Updated:
01/25/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Premature Infant, Chronic Respiratory Disease, Neuromuscular Diseases, Healthy, Bronchopulmonary Dysplasia, Pulmonary Vein Stenoses
PK and Safety in Participants Taking Obicetrapib With Moderate Hepatic Impairment Relative to Normal Hepatic Function
Recruiting
To investigate the safety and pharmacokinetics in patients with moderate hepatic impairment compared to healthy participants after a single oral dose of obicetrapib (10 mg).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
01/20/2024
Locations: Nucleus Network, Saint Paul, Minnesota +1 locations
Conditions: Hepatic Impairment, Healthy