There are currently 241 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
Study of Healthy Cohort for Early Detection of Cancer
NCT05193305
Recruiting
Cancer produces a significant burden on society with a majority diagnosed at late stages when the chance of cure is low. Early diagnosis improves patient outcomes. Data consisting of lifestyle factors, medications, physical activity, years before conventional cancer diagnosis is also worthwhile for to determine early detection. This is only achievable with longitudinal tracking of a large number of healthy individuals and identifying those who do develop cancer over time.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/10/2025
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Healthy
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Effects of GH and Lirglutide on AgRP
NCT05681299
Recruiting
This is a randomized, placebo-controlled, cross-over study with 4 arms. Healthy and GH deficient adults ages 18-45 years will be studied. Arms will consist of 21-day treatment periods and be separated by 8-week washout periods. Subjects will receive, in random order: i) GH alone, ii) GH with liraglutide, iii) liraglutide alone and iv) placebo. Each phase of the study will consist of a 7-day baseline period including 2 days of testing and 21 days on therapy with visits on days 2, 7, 14 and 21. Te... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
02/10/2025
Locations: Neuroendocrine Unit and Pituitary Center, Columbia University Irving Medical Center, New York, New York
Conditions: Growth Hormone Deficiency, Healthy
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Effect of (TaVNS) on Anxiety and Brain Function in Distressed Health Care Workers
NCT05132881
Recruiting
The purpose of this research is to measure alterations in anxiety and brain activity associated with the use of an approved health device called Transauricular Vagal Nerve Stimulation (TaVNS) in distressed persons who work in a health care and distressed healthcare workers in the the Philadelphia, PA region. The Investigators will be using functional magnetic resonance imaging (or fMRI) to measure changes in each subject's brain function during the use of VNS. This study is designed to allow res... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
02/07/2025
Locations: Thomas Jefferson University, Marcus Institute of Integrative Health Centers, Philadelphia, Pennsylvania
Conditions: Anxiety, Distress, Emotional, Effects of Vibration, Healthy
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A Study of Adipose Tissue in Adaptive Responses to Exercise
NCT06053125
Recruiting
The purpose of this research is to determine how exercise affects fat (adipose) tissue and how changes to adipose tissue that occur during and after exercise might improve health in aging and obesity.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/06/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy, Obesity
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Alternation in the Human Microbiome With Commonly Used Topical Medications
NCT03437005
Recruiting
The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: 1. Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. 2. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2025
Locations: University of California, Davis, Department of Dermatology, Sacramento, California
Conditions: Healthy
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Bioenergetic Phenotypes and Cardiometabolic Health
NCT04427462
Recruiting
This research study is about how daily activities, behaviors, and fitness affect the health and function of blood cells and their mitochondria, which are the powerhouses of the cells. These small mitochondria inside the cells make energy, and are very important for the health of the body.
Gender:
ALL
Ages:
Between 8 years and 10 years
Trial Updated:
02/05/2025
Locations: Arkansas Children's Nutrition Center, Little Rock, Arkansas
Conditions: Healthy
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Intraoperative OCT Guidance of Intraocular Surgery II
NCT03713268
Recruiting
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes. The investigators believe this technology will enable novel ophthalmic and other microsurgeries not possible due to current limitations in surgical visualization.
Gender:
ALL
Ages:
4 weeks and above
Trial Updated:
02/03/2025
Locations: Duke University Eye Center, Durham, North Carolina
Conditions: Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment, Retinal Disease, Preretinal Fibrosis, Cataract, Ocular Tumor, Strabismus, Healthy
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Glowing and Expecting Follow Up
NCT03108001
Recruiting
This study will help us learn more about how a mother's health during pregnancy may influence her child's growth and development later in life.
Gender:
ALL
Ages:
Between 5 years and 14 years
Trial Updated:
01/29/2025
Locations: Arkansas Children's Nutrition Center, Little Rock, Arkansas
Conditions: Healthy
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A Phase 1 Study to Evaluate Safety, Tolerability and Pharmacokinetics of TIX100 in Healthy Subjects
NCT06800729
Recruiting
A Single Center, Single Dose, Randomized, Placebo-controlled Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
01/28/2025
Locations: ProSciento, Inc., Chula Vista, California
Conditions: Healthy
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A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease
NCT06057909
Recruiting
The purpose of this research study is to investigate how the brain, memory, thinking, and motor behavior change both in individuals with movement and/or cognitive disorders, as well as healthy individuals. Researchers will look at measurements of memory, thinking, brain wave and muscle activity, daily functioning, and brain scans to learn more about brain disorders such as Alzheimer disease and Lewy body disease.
Gender:
ALL
Ages:
Between 50 years and 95 years
Trial Updated:
01/27/2025
Locations: Mayo Clinic Arizona, Scottsdale, Arizona
Conditions: Lewy Body Disease, Alzheimer Disease, Healthy
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Viral Mucosal Reprogramming
NCT05331170
Recruiting
This is a mechanistic, controlled, open-label, single-site study to evaluate the effects of RG-RV16 inoculation on airway mucosal gene expression and airway remodeling in 25 healthy controls (HC), in 25 allergic rhinitis subjects (AR) with cat dander allergy, and in 25 allergic asthmatic subjects (AA) with cat dander allergy. Three groups (HC, AR, and AA) will undergo screening to establish clinical history, will undergo pulmonary function testing (spirometry), and will have blood drawn for clin... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
01/24/2025
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Asthma, Allergic Rhinitis, Cat Allergy, Healthy
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Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics
NCT05456295
Recruiting
Carbon fiber custom dynamic orthoses (CDOs) consist of a proximal cuff that wraps around the leg just below the knee, a posterior carbon fiber strut that stores and returns energy during gait, and a carbon fiber foot plate that supports the foot and allows bending of the posterior strut. The proximal cuff is a primary interface between the patient and the CDO and may influence comfort, preference, limb mechanics and loading, and effective stiffness of the CDO. The important role of the proximal... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/22/2025
Locations: University of Iowa, Iowa City, Iowa
Conditions: Healthy, Lower Limb Injury, Post-Traumatic Osteoarthritis
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