There are currently 228 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and Maryland.
Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
NCT05337982
Recruiting
The investigators are studying a new rehabilitation treatment for individuals trying to recover walking after spinal cord injury (SCI). The investigators will test conditions in the blood and spinal fluid to determine the best time to start this new training program. This will include checking for certain features called biomarkers by testing participants' spinal fluid and blood and compare these features to individuals without SCI. These features will help investigators determine when to start... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
12/19/2023
Locations: The Ohio State University, Columbus, Ohio +1 locations
Conditions: Spinal Cord Injuries, Healthy
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Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)
NCT05628974
Recruiting
This is a single-center study at the Cleveland Clinic Main Campus designed to study biomarkers in healthy individuals to identify novel mechanisms of platelet activation and how platelets drive vascular inflammation and thrombosis in diseases.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
11/24/2023
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Healthy
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Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
NCT05650112
Recruiting
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2). Eligible participants receive investigational product and undergo safety monitoring, evaluations and subsequent follow-up after investigational product administration.
Gender:
All
Ages:
Between 18 years and 74 years
Trial Updated:
01/23/2023
Locations: Medpace Clinical Pharmacology Unit, Cincinnati, Ohio
Conditions: Healthy, Enteric Hyperoxaluria
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A Study to Test How Avenciguat (BI 685509) is Taken up in the Body of People With and Without Liver Problems
NCT06272058
Recruiting
This study is open to people with and without severe liver problems. People can join the study if they are 18 to 80 years of age and have a body mass index (BMI) between 18.5 and 42 kg/m2. Avenciguat (BI 685509) is a medicine that is being developed to treat high blood pressure in the portal vein (main vessel going to the liver). The purpose of this study is to find out whether having liver problems influences how Avenciguat (BI 685509) is taken up in the body. All participants take Avenciguat... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/30/2024
Locations: Orlando Clinical Research Center, Orlando, Florida +1 locations
Conditions: Healthy, Liver Diseases
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Reward and Drug Effects on Mood and Brain Response
NCT04512365
Recruiting
The goal of the study is to better understand the neural mechanisms underlying the rewarding, reinforcing properties of delta-9-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, among healthy young adults.
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
04/29/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Cannabis Use, Healthy
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Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung
NCT05027958
Recruiting
Background: Tuberculosis (TB) is a lung disease. It is caused by inhaling a type of airborne bacterium. Tuberculin Purified Protein Derivative (PPD) is used to test for TB exposure. It is usually injected under a person s skin. In this study, it will be applied in the lung. Objective: To learn how the cells within the lung react (immune response) when exposed to PPD. Eligibility: Adults ages 18-64 who (1) have been exposed to TB but do not have active disease or symptoms or (2) have never b... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
04/25/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy, Latent Tuberculosis Infection (LTBI)
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RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
NCT05977439
Recruiting
In this research study, the investigators are using examining how brain activity (electrical and blood flow) changes during tests of emotional processing and attention and memory in the magnetic resonance imaging (MRI) scanner. Investigators are also using non-invasive brain stimulation to probe different parts of the brain and measuring brain activity (electrical and blood flow). This study includes healthy participants and researchers hope this will help us develop improved brain-based treatme... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/25/2024
Locations: Medical Univeristy of South Carolina, Charleston, South Carolina
Conditions: Healthy
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A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants
NCT06186622
Recruiting
The main purpose of this study is to determine effect of orforglipron capsule formulation on the amount of digoxin, rosuvastatin, acetaminophen, midazolam, and simvastatin (each given alone and together with orforglipron) that enters the bloodstream and how long it takes the body to eliminate them when administered orally in healthy overweight and obese participants. In addition, the effect of the orforglipron tablet on the amount of simvastatin that enters the bloodstream and how long it takes... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
04/25/2024
Locations: Fortrea Clinical Research Unit Inc., Daytona Beach, Florida +1 locations
Conditions: Healthy, Obese, Overweight
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Interhemispheric Connectivity and Compensation
NCT05207878
Recruiting
The goal of this study is to determine which parts of the brain make it possible for some people to move skillfully with their left non-dominant hand.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/25/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Peripheral Nerve Injury Upper Limb, Healthy
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Study of New Magnetic Resonance Imaging Methods of the Brain
NCT00004577
Recruiting
The purpose of this investigation is to develop improved magnetic resonance imaging (MRI) techniques and hardware for studying brain function. MRI is a diagnostic tool that provides information about brain chemistry and physiology. This study will evaluate new MRI methods for monitoring blood flow to regions of the brain in response to simple tasks. The MRI machine used in this study is more powerful than those in most hospitals, permitting a higher visual resolution. Normal healthy volunteers... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
04/24/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy, Magnetic Resonance Imaging, Adult, Brain Mapping, fMRI, Healthy Volunteer
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A Study to Learn How Different Products of the Study Medicine Called PF-07940367 Are Taken up Into the Blood in Healthy Adults
NCT06190561
Recruiting
The purpose of this study is to compare two finished products of PF-07940367 in terms of the uptake into the blood stream. This study is seeking participants who are: - Healthy male or female participants aged 18 years or older. All participants in this study will receive PF-07940367 once by mouth. The participants may receive different tablets by mouth for PF-07940367. The study will compare experiences of people receiving two different products of PF-07940367. This will help understand how... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Anaheim Clinical Trials, LLC, Anaheim, California
Conditions: Healthy
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Cardiovascular Effects of Exposure to Wood Smoke in Healthy Human Adults
NCT04297761
Recruiting
MASKOFF Clinical Trials 8/22/23 Brief Summary: Purpose: The study is designed to investigate cardiovascular effects of young healthy human subjects exposed to wood smoke. Participants: Approximately 80 young (18-35 years old) healthy subjects to complete. Procedure (methods): After consenting to participate in the study, subjects will be exposed first to filtered air and on the next exposure day to approximately 500 µg/m^3 wood smoke. Both exposures will be 2 hours long with alternating 15 m... Read More
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
04/22/2024
Locations: U.S. Environmental Protection Agency Human Studies Facility, Chapel Hill, North Carolina
Conditions: Healthy
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