There are currently 239 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
Study of Ciraparantag for Reversal of Anticoagulation Induced by Edoxaban, Apixaban or Rivaroxaban in Healthy Adults
NCT04593784
Recruiting
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ciraparantag for reversal of anticoagulation induced by different anticoagulant drugs in generally healthy adults as measured primarily by an automated coagulometer device.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/09/2024
Locations: Qps-Mra, Llc., South Miami, Florida +2 locations
Conditions: Healthy
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Brain Criticality, Oculomotor Control, and Cognitive Effort
NCT06344559
Recruiting
The project examines electroencephalography, MRI, and behavioral measures indexing flexibility (critical state dynamics) in the brain when healthy young adults do demanding cognitive tasks, and in response to transcranial magnetic stimulation.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/05/2024
Locations: Center for Advanced Human Brain Imaging Research, Piscataway, New Jersey
Conditions: Healthy
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Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices
NCT04835857
Recruiting
(1) To compare cuff-less wrist wearable radial artery blood pressure measurements utilizing ViTrack(developed by Dynocardia) to the cuff based commercially available blood pressure device, in healthy volunteers with normal or high blood pressure.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/05/2024
Locations: Dynocardia Inc, Newton, Massachusetts
Conditions: Hypertension, Healthy
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The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots
NCT04985630
Recruiting
Open labelled, virtual home based study to assess the test repeatability and the failure/rejection rate of the samples collected at home by participants.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/05/2024
Locations: Amazentis USA, San Francisco, California
Conditions: Healthy Aging, Healthy, Healthy Diet
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Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota
NCT06528041
Recruiting
The main aim of this study is to investigate differences in rate, extent of change and persistence of the gut microbiota in healthy adult volunteers in response to native chicory inulin. Along with investigating the impact of native chicory on bowl habits, mood and appetite. The two main questions this study aims to answer: * To what extent do differences exist in rate of change over time between individuals in gut microbiota response (Bifidobacterium growth) to native chicory inulin supplement... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/01/2024
Locations: Purdue University, West Lafayette, Indiana
Conditions: Healthy
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Multi-System Analysis of Opioid Receptor Binding
NCT05528848
Recruiting
This study will enroll up to 60 adults (including 30 females and 30 males) in three cohorts of up to 20 subjects each. In all three groups, \[11C\]carfentanil whole-body PET imaging will be used to examine the central nervous system (CNS) and broader systemic opioid binding in an initial scan session. In the two groups not receiving standard of care medication assisted treatment (MAT) for opioid use disorder (OUD) the effects on \[11C\]carfentanil binding potential of the blockade of opioid bind... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
07/23/2024
Locations: University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania
Conditions: Healthy, Opioid Use Disorder
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Endothelial Derived Hyperpolarization Factor and Vascular Control
NCT05176379
Recruiting
Most cardiometabolic diseases are characterized by increased muscle sympathetic nerve activity (MSNA) during rest and exercise which contributes to poor health outcomes. In healthy humans during muscle contraction, there is a blunting of skeletal muscle vascular responsiveness to increases in MSNA. However, the exact mechanisms involved are unknown although, best evidence suggests that the mechanism is endothelium derived, but nitric oxide (NO) and prostaglandin (PG) independent. Endothelium-der... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
07/19/2024
Locations: Department of Health and Exercise Science, Norman, Oklahoma
Conditions: Healthy
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Characterization of Gastric Evoked Potentials
NCT05924009
Recruiting
This is an exploratory study that will determine and standardize how best to record gastric evoked potentials (GEPs) elicited by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS), by optimizing the TMS parameters and cortical sites necessary to evoke GEPs.
Gender:
ALL
Ages:
Between 21 years and 60 years
Trial Updated:
07/15/2024
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Healthy
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Fluid Loading Countermeasures
NCT06467812
Recruiting
The purpose of Fluid Loading Countermeasures is to determine how the volume of blood and of plasma (liquid part of blood) change during a normal day, how these are affected by drinking an additional amount of fluid either as water and salt tablets (as astronauts do) or an electrolyte beverage (similar to but tastes saltier than Gatorade®), and how altering the timing at which the additional fluid is consumed affects blood and plasma volume. This study observes how blood volume changes over \~9 h... Read More
Gender:
ALL
Ages:
Between 25 years and 55 years
Trial Updated:
07/08/2024
Locations: NASA, Houston, Texas
Conditions: Healthy
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Identification of Biomarkers for Stress Vulnerability and Resilience
NCT05498207
Recruiting
The purpose of this research study is to understand the biological mechanisms of stress vulnerability (being susceptible to stress) and stress resilience (being able to recover readily from stress), obtain biomarkers (a biological indicator) for stress resilience and to devise strategies for prevention and treatment of stress-related disorders.
Gender:
ALL
Ages:
Between 18 years and 22 years
Trial Updated:
07/08/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Healthy
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Effects of Experimental Sleep Disturbances on Receptor Function of Study Drug
NCT04299490
Recruiting
The overall goal of this project is to determine whether common sleep disturbance patterns, sleep continuity disturbance (SCD) and Sleep Fragmentation (SF), alter cerebral study drug receptor availability, drug-based analgesia, and drug abuse liability. The investigators specifically aim to: 1) evaluate whether experimental SCD and/or SF alter resting or pain-evoked receptor binding potential in brain regions associated with pain inhibition; 2) examine whether SCD and/or SF alters the analgesic... Read More
Gender:
ALL
Ages:
Between 18 years and 48 years
Trial Updated:
07/01/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Sleep Disorder, Healthy
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tFUS Induced Transient Scotoma for Individual Dosing
NCT06426498
Recruiting
The purposes of this research study is to: 1. Develop a technique of transcranial Focused Ultrasound Stimulation (tFUS) where meaningful effects on the brain can be easily measured. 2. Use this technique to measure threshold for effective tFUS in individuals. 3. Determine whether disruption of conscious visual detection, versus non-conscious visually-guided behavior have different thresholds for disruption with tFUS.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/01/2024
Locations: Medical University of South Carolina Brain Stimulation Division, Charleston, South Carolina
Conditions: Healthy
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