There are currently 241 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
Investigating Electroencephalographic Predictors of Default Mode Network Anticorrelation in Healthy Adults
NCT05592600
Recruiting
Healthy adult subjects will participate in two sessions. The first session will involve measurements of brain activity using simultaneous recordings with electroencephalography (EEG) and functional Magnetic Resonance Imaging (fMRI). During brain activity measurement, participants will perform cognitive tasks assessing attention. The second will involve fMRI-based neurofeedback during simultaneous EEG-fMRI recording. Participants will receive real-time visual feedback of signals measured from spe... Read More
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
11/06/2023
Locations: Drexel University, Philadelphia, Pennsylvania
Conditions: Healthy
Register for Updates
Effects of MIB-626 With and Without A High-Intensity Multi-Dimensional Exercise Training Program
NCT05878119
Recruiting
A single-center, randomized, placebo-controlled study in community dwelling, healthy, regularly exercising, highly physically fit men and women, 19 to 40 years. Eligible participants will be randomized to receive either 1000 mg NMN or placebo twice daily for 10 weeks.
Gender:
ALL
Ages:
Between 19 years and 40 years
Trial Updated:
11/01/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Healthy
Register for Updates
MAD Study of IA-14069
NCT05533372
Recruiting
The purpose of this study is to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending oral doses of IA-14069 in healthy subjects and in patients with RA on stable dosese of MTX, with preliminary assessment of efficacy in RA patients.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
10/11/2023
Locations: ICON plc., Lenexa, Kansas
Conditions: Healthy, Rheumatoid Arthritis
Register for Updates
To Study the Oral Bioavailability of a New Combination Formation of Decitabine and Tetrahydrouridine in Healthy Males
NCT05816356
Recruiting
This is an open-label, randomized, single-dose per period, two-period, crossover study to evaluate the relative bioavailability of decitabine and tetrahydrouridine ingested as a modified-release combination formulation compared to THU and decitabine ingested as immediate-release capsules
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
09/05/2023
Locations: Worldwide Clinical Trails Early Phase Services, San Antonio, Texas
Conditions: Healthy
Register for Updates
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
NCT00573339
Recruiting
The purpose of this research is to understand how to apply cardiac magnetic resonance imaging (CMR) to women with small artery heart disease by looking at the CMRs of women without heart disease. The investigators will study 40 women with no heart disease to learn more about the usefulness of CMR. Women suffer more than men from this disorder of the small vessels compared to the large vessels. This results in delays in diagnosis, missed opportunities for treatment, and likely contributes to the... Read More
Gender:
FEMALE
Ages:
Between 35 years and 65 years
Trial Updated:
08/30/2023
Locations: Cedars-Sinai Women's Heart Center, Los Angeles, California
Conditions: Healthy
Register for Updates
Imaging Brain Fluids During Breathing
NCT05180981
Recruiting
This study will perform magnetic resonance imaging (MRI) measurements of hemodynamics and cerebrospinal fluid flow across breathing tasks and during breath-locked neuromodulation.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/14/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Healthy
Register for Updates
Lower Extremity BFR-randomized Controlled Trial Healthy Volunteers
NCT05868304
Recruiting
The purpose of this research is to determine the effects of low-load blood flow restriction (BFR) training compared to conventional strengthening using dynamic force plate and isometric force frame analyses in healthy subjects.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/10/2023
Locations: Cedar Sinai Kerlan jobe orthopedic institute, Los Angeles, California
Conditions: Healthy
Register for Updates
Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments, Using Multiomics
NCT05736029
Recruiting
The goal of this exploratory study is understand the mechanisms of response to immunotherapy in Non-Small Cell Lung Cancer patients. The investigators are going to search for correlation between specific biological features and response to immunotherapy, and to use those associations for developing an algorithm enabling to identify patients that could benefit from the immune check inhibitor based anti cancer treatment. Patients will provide biological samples before and during their treatment,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/09/2023
Locations: Baylor Scott and White Research Institute, Dallas, Texas
Conditions: Non Small Cell Lung Cancer, Healthy
Register for Updates
Selective PET Imaging of Astrocytes and Microglia in Alzheimer's Disease
NCT05582200
Recruiting
Inflammation occurs in many brain diseases including Alzheimer's disease. In Alzheimer's disease, amyloid starts accumulating decades before the start of forgetfulness. Basic scientists have reported that inflammation but not amyloid is linked to forgetfulness. When people pinch a finger, it gets swollen. Similar changes occur in brain from various causes. New medications are under development to help healing and prevent permanent damages in the brain. When people pinch a finger, they can check... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
01/20/2023
Locations: Houston Methodist Research Institute, Houston, Texas
Conditions: Alzheimer Disease, Healthy
Register for Updates
Collection and Distribution of Biospecimens for Novel Research Uses
NCT03848962
Recruiting
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with annotated biospecimens for use in biomarker discovery and validation; diagnostic test and instrumentation development and validation; therapeutics development; other medical research including the impact that various specimen collection and handling methods and conditions have... Read More
Gender:
ALL
Ages:
Between 1 month and 89 years
Trial Updated:
11/08/2022
Locations: iSpecimen, Huntsville, Alabama +1 locations
Conditions: Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases, Infectious Disease, Women's Health: High-Risk Pregnancy, Dermatologic Disease, Blood Disease
Register for Updates
New Orleans Pulmonary Hypertension Biobank
NCT03269630
Recruiting
Pulmonary hypertension (PH) is a serious condition characterized by a mean pulmonary artery pressure \>=25mmHg on right heart catheterization (RHC). Despite advances in PH care, outcomes are still sub-optimal and further research is required into the pathobiology of the disease and development of biomarkers that can guide clinical care. The investigators are establishing a biobank to collect samples (blood, urine, stool) from patients with pulmonary hypertension, patients at high risk for pulmon... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2021
Locations: University Medical Center-New Orleans, New Orleans, Louisiana
Conditions: Pulmonary Hypertension, Systemic Sclerosis, Mixed Connective Tissue Disease, Heart Failure With Normal Ejection Fraction, Healthy
Register for Updates
A SAD/MAD Study to Evaluate the Safety, Tolerability, PK and PD of MT2004
NCT04768452
Recruiting
This is a randomized, double-blind, placebo-controlled, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of a single dose of MT2004 following oral single and multiple ascending dose administration.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
02/20/2021
Locations: Pharmaron CPC, Baltimore, Maryland
Conditions: Healthy
Register for Updates