There are currently 241 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
Real-time fMRI for Insular Cortex Brain State-triggered Experience Sampling
NCT05855525
Recruiting
In a neuroimaging session, study participants will repeatedly and intermittently report the content of their ongoing, self-generated experiences based on an experience-sampling protocol in which self-report ratings will be triggered based on real-time analysis of the participant's current brain state. The protocol will be conducted while participants are undergoing MRI scanning.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
08/21/2024
Locations: Drexel University, Philadelphia, Pennsylvania
Conditions: Healthy
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Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound
NCT03192436
Recruiting
Neuromodulation is a fast growing field that offers a wide range of applications for both understanding and treating the brain. Future research for non-invasive neuromodulation will need to elucidate the optimal frequency, duration, and intensity of stimulation for a variety of technologies and diseases. Closed loop stimulation is thus a promising research area that allows for responsive stimulation and real time symptom management. Our project is proposed to develop and test a novel noninvasive... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
08/19/2024
Locations: Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania
Conditions: Healthy
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Testing the Contribution of Orbitofrontal Cortex Networks to Decision-making
NCT05111223
Recruiting
This research study examines the contribution of orbitofrontal cortex (OFC) networks to decision-making.
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
08/16/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Healthy
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A Phase 1 Safety and Tolerability Study of TML-6 in Healthy and Elderly Volunteers for Alzheimer's Disease Treatment
NCT06562114
Recruiting
The purpose of this study is to evaluate the safety, tolerability, single-ascending dose (SAD), multiple-ascending dose (MAD), food effect, and pharmacokinetic (PK) Study of TML-6.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/15/2024
Locations: Parexel International, Glendale, California
Conditions: Healthy
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CBD-Microglia PET Study
NCT04398719
Recruiting
This study aims to examine the effect of cannabidiol (CBD) pre-treatment on brain microglial activation in healthy human subjects. Secondarily, this study aims to examine the effect of cannabidiol (CBD) pre-treatment on central pain-sensitization in healthy human subjects.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
08/14/2024
Locations: Connecticut Mental Health Center, New Haven, Connecticut
Conditions: CBD, Healthy
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Study of Ciraparantag for Reversal of Anticoagulation Induced by Edoxaban, Apixaban or Rivaroxaban in Healthy Adults
NCT04593784
Recruiting
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ciraparantag for reversal of anticoagulation induced by different anticoagulant drugs in generally healthy adults as measured primarily by an automated coagulometer device.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/09/2024
Locations: Qps-Mra, Llc., South Miami, Florida +2 locations
Conditions: Healthy
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Brain Criticality, Oculomotor Control, and Cognitive Effort
NCT06344559
Recruiting
The project examines electroencephalography, MRI, and behavioral measures indexing flexibility (critical state dynamics) in the brain when healthy young adults do demanding cognitive tasks, and in response to transcranial magnetic stimulation.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/05/2024
Locations: Center for Advanced Human Brain Imaging Research, Piscataway, New Jersey
Conditions: Healthy
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The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots
NCT04985630
Recruiting
Open labelled, virtual home based study to assess the test repeatability and the failure/rejection rate of the samples collected at home by participants.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/05/2024
Locations: Amazentis USA, San Francisco, California
Conditions: Healthy Aging, Healthy, Healthy Diet
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Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices
NCT04835857
Recruiting
(1) To compare cuff-less wrist wearable radial artery blood pressure measurements utilizing ViTrack(developed by Dynocardia) to the cuff based commercially available blood pressure device, in healthy volunteers with normal or high blood pressure.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/05/2024
Locations: Dynocardia Inc, Newton, Massachusetts
Conditions: Hypertension, Healthy
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Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota
NCT06528041
Recruiting
The main aim of this study is to investigate differences in rate, extent of change and persistence of the gut microbiota in healthy adult volunteers in response to native chicory inulin. Along with investigating the impact of native chicory on bowl habits, mood and appetite. The two main questions this study aims to answer: * To what extent do differences exist in rate of change over time between individuals in gut microbiota response (Bifidobacterium growth) to native chicory inulin supplement... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/01/2024
Locations: Purdue University, West Lafayette, Indiana
Conditions: Healthy
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Multi-System Analysis of Opioid Receptor Binding
NCT05528848
Recruiting
This study will enroll up to 60 adults (including 30 females and 30 males) in three cohorts of up to 20 subjects each. In all three groups, \[11C\]carfentanil whole-body PET imaging will be used to examine the central nervous system (CNS) and broader systemic opioid binding in an initial scan session. In the two groups not receiving standard of care medication assisted treatment (MAT) for opioid use disorder (OUD) the effects on \[11C\]carfentanil binding potential of the blockade of opioid bind... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
07/23/2024
Locations: University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania
Conditions: Healthy, Opioid Use Disorder
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Endothelial Derived Hyperpolarization Factor and Vascular Control
NCT05176379
Recruiting
Most cardiometabolic diseases are characterized by increased muscle sympathetic nerve activity (MSNA) during rest and exercise which contributes to poor health outcomes. In healthy humans during muscle contraction, there is a blunting of skeletal muscle vascular responsiveness to increases in MSNA. However, the exact mechanisms involved are unknown although, best evidence suggests that the mechanism is endothelium derived, but nitric oxide (NO) and prostaglandin (PG) independent. Endothelium-der... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
07/19/2024
Locations: Department of Health and Exercise Science, Norman, Oklahoma
Conditions: Healthy
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