There are currently 226 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and Maryland.
Early Detection of Vascular Dysfunction Using Biomarkers From Lagrangian Carotid Strain Imaging
Recruiting
The purpose of this research is assess imaging and identification of soft plaque that undergoes large deformations or strain will identify plaque vulnerable to rupture which could lead to 'silent strokes'. Validation of current study results with MRI will foster use of real-time ultrasound (US) strain imaging and strain indices as a screening tool for identifying normal human participants susceptible to increased vascular aging and developing plaque prone to rupture or micro-embolization. Curre... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: Department of Medical Physics, University of Wisconsin, Madison, Wisconsin
Conditions: Healthy, Carotid Artery Diseases
Brain Changes in Psoriasis After Secukinumab Treatment
Recruiting
The purpose of this study is to assess the effect of a biologic drug targeting the Interleukin (IL)-17 pathway (secukinumab) on brain plasticity and examine whether the plastic changes correlate with the improvement of perception of well-being, itch, and pain in participants with psoriasis.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/18/2024
Locations: University of Miami, Miami, Florida
Conditions: Psoriasis, Healthy
Longitudinal At Home Smell Testing to Detect Infection by SARS-CoV-2
Recruiting
The purpose of this study is to learn more about how to better track smell recovery in people who have been infected with the SARS-CoV-2 virus (which causes COVID-19). Many people who have been infected by this virus develop changes in their sense of smell (olfaction). We are interested in measuring smell function objectively via smell cards that test odor intensity, identification, and discrimination. Objective and precise olfactory testing that can be performed in the convenience of one's home... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
03/18/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Anosmia, Asymptomatic COVID-19, COVID-19 Respiratory Infection, Influenza, Healthy
Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought
Recruiting
This research study will use computerized tasks, electroencephalography (EEG), and magnetic resonance imaging (MRI) to look at how the drug psilocybin, a naturally occurring compound contained in hundreds of species of psychoactive mushrooms, changes thoughts and brain activity.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/13/2024
Locations: Johns Hopkins Center for Psychedelic and Consciousness Research, Baltimore, Maryland
Conditions: Healthy
Project 2 Airway Potential Hydrogen (pH) in Asthma
Recruiting
This study is testing a non invasive way to measure airway pH in individuals with Asthma and Cystic Fibrosis using a new inhaled drug. The airway pH will help health care providers in creating tailored treatment plans for individuals suffering from these specific conditions.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
03/13/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana +1 locations
Conditions: Cystic Fibrosis, Asthma, Severe Persistent Asthma, Healthy
Engineering Evaluation of a Breast Pump Device
Recruiting
This research involves feasibility testing of design concepts to support device development of an electric breast pump. The purpose is to evaluate a prototype device for feasibility purposes and not health outcomes.
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Blur Product Development, Cary, North Carolina
Conditions: Healthy, Breast Pumping
Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function
Recruiting
This study is being done to assess the effects of S. boulardii CNCM I-745 compared to placebo on impaired intestinal permeability, which is the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall into the rest of the body.
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
03/11/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
Pharmacokinetics of Transdermal Metronidazole
Recruiting
This is a crossover pharmacokinetic clinical study in healthy volunteers to compare metronidazole delivery through skin when a gel or cream metronidazole product is applied to skin treated with a micropatch.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/10/2024
Locations: University of Iowa, Iowa City, Iowa
Conditions: Healthy
LPFC Organization in Emotion-Duration Difference Estimation
Recruiting
To support optimal behavior in daily life, goals and responses following emotional events should ideally incorporate not only the valence and intensity of prior emotional episodes but also their temporal features, such as the relative duration of positive vs. negative attributes. However, how specific brain regions contribute to the integration of temporal and emotional information and promote goal-directed response remains unknown. The goal of this study is to examine how specific brain region... Read More
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
03/04/2024
Locations: University of California, Santa Barbara, Santa Barbara, California
Conditions: Healthy
Adipose Tissue Blood Flow in Aging Humans
Recruiting
The goal of this basic science clinical trial is to understand whether adipose tissue blood flow changes between younger and older healthy adults. The main question[s] it aims to answer are: Is basal and nutrient responsive adipose tissue blood flow (ATBF) different between younger and older adults What molecular and systemic signatures related to adipose tissue blood flow are altered between these two groups. Participants will undergo measurements of adipose tissue blood flow using the xenon... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/28/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Healthy, Aging
SV2A Density Cannabis Use Disorder
Recruiting
The main purpose of this study is to determine whether hippocampal synaptic vesicle density estimated by hippocampal [11C]APP-311/[11C]UCB-J binding in individuals diagnosed with cannabis use disorder (CUDs) improves with at least 4 weeks of confirmed abstinence from cannabis, in comparison to healthy controls (HCs). Furthermore, any change in synaptic vesicle density will be placed in functional context by measuring verbal memory, which is sensitive to hippocampal function, before and after at... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/28/2024
Locations: Yale University School of Medicine, New Haven, Connecticut
Conditions: Cannabis Use Disorder, Healthy
Clinical Trial of Two Study Drinks in Detoxification of Environmental Toxicants and Carcinogens
Recruiting
The goal of this research is to determine if consuming one of two study drinks will help enhance the detoxification of multiple environmental toxicants and cancer causing agents, particularly in subjects who are null for glutathione-S-transferase M1 (GSTM1), glutathione-S-transferase T1 (GSTT1), or both. If our research supports this idea, this drink could be an inexpensive dietary component, which could promote good health.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Healthy