There are currently 231 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
Influence of Brain Oscillation-Dependent TMS on Motor Function
Recruiting
Background: When people have a stroke, they often have difficulty moving their arms and hands. Transcranial magnetic stimulation (TMS) can improve how well people with and without stroke can move their arms and hands. But the effects of TMS are minor, and it doesn t work for everyone. Researchers want to study how to time brain stimulation so that the effects are more consistent. Objective: To understand how the brain responds to transcranial magnetic stimulation so that treatments for people... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy, Stroke, Normal Physiology, Aging
Effectiveness of Aquamin® in Mitigating Halitosis
Recruiting
The purpose of this study is to assess whether Aquamin®, a multi-mineral natural product from red marine algae, can help reduce halitosis when taken for 90 days.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/03/2024
Locations: University of Michigan School of Dentistry, Ann Arbor, Michigan
Conditions: Healthy, Halitosis
The Effects of External Nasal Dilator Strips on Sleep and Cardiovascular Health
Recruiting
The goal of this interventional study is to learn if wearing an external nasal dilator strip while sleeping changes objective and perceived sleep quality, immediate post-waking blood pressure, and immediate-post waking heart rate variability.
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
05/03/2024
Locations: Cardiovascular and Applied Physiology Laboratory, Tallahassee, Florida
Conditions: Healthy
Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity
Recruiting
Patients with sleep apnea are at increased risk of developing cardiovascular disease - with women at potentially greater risk than men. Contributing mechanisms are not well understood, but may be related to how women respond to low oxygen and, given over 70% of patients with sleep apnea are obese, the impact of obesity. This project seeks to increase our understanding of mechanisms that may contribute to sex differences in the cardiovascular response to low oxygen with the hope that this knowled... Read More
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
05/02/2024
Locations: University of Missouri-Columbia, Columbia, Missouri
Conditions: Obesity, Healthy, Vasoconstriction, Vasodilation
Imaging mGluR5 and Synaptic Density in Psychiatric Disorders
Recruiting
This research study is designed to look at the involvement of the glutamate system and synaptic density in depression and bipolar disorder. Each participant will undergo a screening appointment to determine study eligibility. Thereafter, the study will take 2 or 3 visits depending on schedule availability and will consist of a combination of one magnetic resonance imaging (MRI) or functional magnetic resonance imaging (fMRI) scan, one proton magnetic resonance spectroscopy (MRS) and/or one C13 M... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/02/2024
Locations: Yale University PET Center, New Haven, Connecticut
Conditions: Major Depressive Disorder, Bipolar Disorder, Healthy
A First-in-Human Safety Trial of MTX-463
Recruiting
A randomized, double-blind, placebo-controlled, single ascending dose (SAD) and multiple ascending dose (MAD) study to assess the safety, tolerability, and PK of single and multiple ascending doses of MTX-463 administered in healthy adults.
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/02/2024
Locations: ICON, Salt Lake City, Utah
Conditions: Healthy
1a/1b Study of OPT101 First in Human Study Assessing Safety and Tolerability of 15-mer Peptide.
Recruiting
This is a first-in-human study, Phase 1, randomized, placebo-controlled, double blinded study that will be conducted in 2 parts.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
05/01/2024
Locations: IMMUNOe Research, Centennial, Colorado
Conditions: Healthy
A Study to Test How Avenciguat (BI 685509) is Taken up in the Body of People With and Without Liver Problems
Recruiting
This study is open to people with and without severe liver problems. People can join the study if they are 18 to 80 years of age and have a body mass index (BMI) between 18.5 and 42 kg/m2. Avenciguat (BI 685509) is a medicine that is being developed to treat high blood pressure in the portal vein (main vessel going to the liver). The purpose of this study is to find out whether having liver problems influences how Avenciguat (BI 685509) is taken up in the body. All participants take Avenciguat... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/30/2024
Locations: Orlando Clinical Research Center, Orlando, Florida +1 locations
Conditions: Healthy, Liver Diseases
Reward and Drug Effects on Mood and Brain Response
Recruiting
The goal of the study is to better understand the neural mechanisms underlying the rewarding, reinforcing properties of delta-9-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, among healthy young adults.
Gender:
All
Ages:
Between 18 years and 25 years
Trial Updated:
04/29/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Cannabis Use, Healthy
Interhemispheric Connectivity and Compensation
Recruiting
The goal of this study is to determine which parts of the brain make it possible for some people to move skillfully with their left non-dominant hand.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/25/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Peripheral Nerve Injury Upper Limb, Healthy
RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
Recruiting
In this research study, the investigators are using examining how brain activity (electrical and blood flow) changes during tests of emotional processing and attention and memory in the magnetic resonance imaging (MRI) scanner. Investigators are also using non-invasive brain stimulation to probe different parts of the brain and measuring brain activity (electrical and blood flow). This study includes healthy participants and researchers hope this will help us develop improved brain-based treatme... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/25/2024
Locations: Medical Univeristy of South Carolina, Charleston, South Carolina
Conditions: Healthy
Mapping Auricular Vagus Nerve Circuitry
Recruiting
This study will determine how noninvasive nerve stimulation affects human brain, stomach, and autonomic activity.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/22/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Healthy