There are currently 243 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
A Trial to Evaluate Tolerability and Immunogenicity of V540D in Healthy Adults (V540D-004)
NCT06688058
Recruiting
Researchers are looking for new ways to prevent cancers related to human papillomavirus (HPV). HPV is a common virus that can cause an infection. There are many different types of HPV. Most people's immune system can fight HPV infection and it goes away without treatment. For some people, HPV infections can last longer and may cause cancer years later. A standard vaccine to prevent HPV-related cancers is GARDASIL®9 (G9). G9 protects against 9 types of HPV but it does not protect against other t... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
01/27/2025
Locations: Research Centers of America ( Hollywood ) ( Site 0001), Hollywood, Florida
Conditions: Healthy
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Viral Mucosal Reprogramming
NCT05331170
Recruiting
This is a mechanistic, controlled, open-label, single-site study to evaluate the effects of RG-RV16 inoculation on airway mucosal gene expression and airway remodeling in 25 healthy controls (HC), in 25 allergic rhinitis subjects (AR) with cat dander allergy, and in 25 allergic asthmatic subjects (AA) with cat dander allergy. Three groups (HC, AR, and AA) will undergo screening to establish clinical history, will undergo pulmonary function testing (spirometry), and will have blood drawn for clin... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
01/24/2025
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: Asthma, Allergic Rhinitis, Cat Allergy, Healthy
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A Study of LY3437943 in Participants With Impaired and Normal Liver Function
NCT05916560
Recruiting
The main purpose of this study is to measure how much of LY3437943 gets into the bloodstream and how long it takes the body to eliminate it in participants with mild, moderate and severe impaired liver function compared to healthy participants with normal liver function. The safety and tolerability of LY3437943 will also be evaluated. The study may last up to 9 weeks for each participant including the screening period.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/24/2025
Locations: Arizona Clinical Trials - Chandler, Chandler, Arizona +4 locations
Conditions: Healthy, Hepatic Insufficiency
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Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors
NCT00785525
Recruiting
The purpose of the study is to: * Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors * Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis * Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated donor hematopoietic stem cell transplant recipients * Determine the acceptability of stem cell donation by filgrastim stimulated apheresis in nor... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
01/23/2025
Locations: Gift of Life Bone Marrow Foundation, Boca Raton, Florida +3 locations
Conditions: Healthy
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Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics
NCT05456295
Recruiting
Carbon fiber custom dynamic orthoses (CDOs) consist of a proximal cuff that wraps around the leg just below the knee, a posterior carbon fiber strut that stores and returns energy during gait, and a carbon fiber foot plate that supports the foot and allows bending of the posterior strut. The proximal cuff is a primary interface between the patient and the CDO and may influence comfort, preference, limb mechanics and loading, and effective stiffness of the CDO. The important role of the proximal... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/22/2025
Locations: University of Iowa, Iowa City, Iowa
Conditions: Healthy, Lower Limb Injury, Post-Traumatic Osteoarthritis
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A Study of Olomorasib (LY3537982) in Participants With Hepatic Impairment and Healthy Participants
NCT06719128
Recruiting
The main purpose of this study is to assess how olomorasib gets into the blood stream and how long it takes the body to remove it when administered to participants with mild, moderate and severe impaired liver function compared to participants with normal liver function. The safety and tolerability of olomorasib will also be evaluated. The study may last up to 6 weeks for each participant including the screening period.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/22/2025
Locations: Orange County Research Center, Lake Forest, California +3 locations
Conditions: Hepatic Insufficiency, Healthy
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Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff
NCT06127264
Recruiting
The primary purpose of this research study is to determine if forces within carbon fiber custom dynamic orthoses (CDOs) can be reliability assessed using Loadpad and Loadsol force measuring sensors (Novel GMBH, St. Paul, MN). An improved understanding of the forces acting within orthoses may help to guide future orthosis related research studies, provision methods, and patient education. Study participants will consist of two groups; 1) healthy, able-bodied adult participants using generic size... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
01/22/2025
Locations: University of Iowa, Iowa City, Iowa
Conditions: Healthy, Ankle Foot Orthosis (AFO)
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Blood Flow Restriction (BFR) Training on the Ulnar Collateral Ligament (UCL)
NCT06664827
Recruiting
The goal of this clinical trial is to identify any differences in elbow ulnar collateral ligament (UCL) relative thickness and joint space laxity in the dominant arm following an 8-week course of low intensity resistance exercises with blood flow restriction (BFR) exercises in healthy volunteers. The main questions it aims to answer are: 1. Do BFR exercises contribute to a change in the relative ligament thickness of the UCL, and changes in the ulnohumeral joint space? 2. Are there changes in a... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
01/21/2025
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Healthy, Healthy Male and Female Subjects, Healthy Volunteers
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Clinical Study to Assess the Effects of Prebiotic and Probiotic Supplement
NCT06794619
Recruiting
Randomized, Crossover, Double-Blind, Placebo-Controlled, Single-Center Clinical Study with Daily Food Log, Stool Samples, Blood Draws, and Validated Questionnaires (GSRS, Bristol stool chart, and DQLQ) with Oral Dietary Supplement
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
01/21/2025
Locations: Princeton Consumer Research, Saint Petersburg, Florida
Conditions: Healthy
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The Accuracy of a Novel Platelet Activity Assay in Humans on Antiplatelet Agents: Pharmacodynamics and Comparison with Light Transmission Aggregometry
NCT04822363
Recruiting
The purpose of this study is to test a novel diagnostic immunoassay of platelet function and compare it to the current gold standard platelet function assay by testing the response to aspirin and clopidogrel in a group of healthy volunteers and severely obese individuals and comparing the accuracy of the two tests. The secondary goals will be to evaluate the pharmacodynamic parameters of the antiplatelet agents across the two testing modalities and refine the cutoffs used for the novel assay.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2025
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Platelet Activation Testing Before/After Anti-platelet Therapy, Healthy
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SV2A Density Cannabis Use Disorder
NCT05472818
Recruiting
The main purpose of this study is to determine whether hippocampal synaptic vesicle density estimated by hippocampal \[11C\]APP-311/\[11C\]UCB-J binding in individuals diagnosed with cannabis use disorder (CUDs) improves with at least 4 weeks of confirmed abstinence from cannabis, in comparison to healthy controls (HCs). Furthermore, any change in synaptic vesicle density will be placed in functional context by measuring verbal memory, which is sensitive to hippocampal function, before and after... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/21/2025
Locations: Yale University School of Medicine, New Haven, Connecticut
Conditions: Cannabis Use Disorder, Healthy
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The BrainHealth Project
NCT04869111
Recruiting
For an overview of the study and link TO REGISTER please go to -- https://brainhealth.utdallas.edu/programs/the-brainhealth-project/ The BrainHealth Project is a ten-year, longitudinal study focused on identifying determinants of brain health and performance. Participants will have the opportunity to complete semi-annual (twice a year) online assessments to track their performance over time. In between semi-annual assessments, participants will have access to online trainings and ongoing supple... Read More
Gender:
ALL
Ages:
Between 18 years and 110 years
Trial Updated:
01/21/2025
Locations: The Center for BrainHealth at The University of Texas at Dallas, Dallas, Texas
Conditions: Healthy
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