There are currently 239 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study
NCT06220396
Recruiting
The purpose of this study is to evaluate pulmonary capillary wedge pressure (PCWP) and other hemodynamic measurements at rest and during exercise in healthy volunteers across the age spectrum.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/08/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
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Studying the Hedonic and Homeostatic Regulation of Food Intake Using Functional MRI
NCT05525845
Recruiting
The purpose of this study is to investigate how gut hormones and brain areas respond differently to gastric distention, tasteless calories, or palatable food and how this alters appetite.
Gender:
ALL
Ages:
Between 21 years and 50 years
Trial Updated:
01/07/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy
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Effects of Caffeine on Reinforcement Learning in Healthy Adults Using PET/MRI
NCT06763172
Recruiting
This research study aims to determine whether and how caffeine intake affects learning process through reward feedback compared to placebo. The data acquired from this study would improve our understanding on the consequence and mechanism of caffeine intake in the aspect of learning process. Participants will perform a reinforcement learning task (i.e. Probabilistic Selection Task) and a motor inhibition task (i.e. Go/NoGo task) in a brain scan. The scan will be done with the Siemens Biograph m... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
01/07/2025
Locations: Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts
Conditions: Healthy, Caffeine, Adenosine, Dopamine D2/3 Receptor Availability
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NPWT Reduction Mammaplasty
NCT06725459
Recruiting
In this prospective, randomized, split-body control trial, we aim to compare complications, patient-reported outcomes, and cost differentials following reduction mammaplasty with prophylactic closed incision negative pressure wound therapy versus standard adhesive dressing.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
01/03/2025
Locations: Medstar Georgetown University Hospital, Washington, District of Columbia
Conditions: Healthy, Macromastia, Negative Pressure Therapy, Mammaplasty, Wound Healing
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Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function
NCT05538247
Recruiting
This study is being done to assess the effects of S. boulardii CNCM I-745 compared to placebo on impaired intestinal permeability, which is the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall into the rest of the body.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
01/02/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
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How Does the Type of Waveform Affect Tolerability With Transcutaneous Auricular Vagus Nerve Stimulation?
NCT06614933
Recruiting
The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS). The research team is interested in how the different forms affect comfort and tolerability, as well as how well it works.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
12/29/2024
Locations: University of Miami, Plumer Building, Coral Gables, Florida
Conditions: Healthy
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Dinner Time 2: Effect of Delayed Eating or Sleeping on Metabolism
NCT04671797
Recruiting
This study examines the acute impact of eating an "early" versus "late" dinner. "Early" and "late" will be customized to individuals based on the individuals' own circadian rhythms. Healthy adults will have the adults' circadian rhythm assessed by measuring the adults' dim light melatonin onset (DLMO). Based on the timing of DLMO, participants will be randomized to eating dinner before DLMO or after DLMO. The investigators will also compare the effects of delaying sleep relative to dinner time.... Read More
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
12/17/2024
Locations: Johns Hopkins Bayview Medical Center, Baltimore, Maryland
Conditions: Healthy
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Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought
NCT05301608
Recruiting
This research study will use computerized tasks, electroencephalography (EEG), and magnetic resonance imaging (MRI) to look at how the drug psilocybin, a naturally occurring compound contained in hundreds of species of psychoactive mushrooms, changes thoughts and brain activity.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
12/16/2024
Locations: Johns Hopkins Center for Psychedelic and Consciousness Research, Baltimore, Maryland
Conditions: Healthy
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Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
NCT03759522
Recruiting
The primary objective of this study is to measure the concentration and the regional brain distribution of activated brain microglia/macrophages using the PET radiopharmaceutical \[F-18\]DPA-714 in individuals with chronic pain and fatigue suspected to be associated with neuroinflammation. The PET tracer \[F-18\]DPA-714 binds to the 18 kDa translocator protein (TSPO, also known as the peripheral benzodiazepine receptor) in the mitochondria of activated microglia/macrophages and provides a non-in... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/13/2024
Locations: University of Alabama at Birmingham Medical Center, Birmingham, Alabama
Conditions: Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, Healthy
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The Longitudinal Study of Stimulant Use Disorder
NCT06073340
Recruiting
This research is a 5-year observational, longitudinal registry study with no treatment or medication provided as part of participation. Individuals with current or lifetime stimulant use disorder, in addition to healthy control individuals, may be eligible to participate in this study. A variety of assessments and tasks including Magnetic Resonance Imaging (MRI), Electroencephalography (EEG), blood draws, urine drug screens, and both self-report and clinician-rated assessments will be used to as... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
12/13/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Stimulant Use, Stimulant-Related Disorder, Healthy
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The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation
NCT04831398
Recruiting
the purpose of this experiment is to determine if acute melatonin supplementation alters central and peripheral cardiovascular responses to a cold pressor test at rest and during dynamic exercise.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
12/05/2024
Locations: Department of Health and Exercise Science, Norman, Oklahoma
Conditions: Healthy
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Carbon Dioxide (CO2) and Cognitive Impairment
NCT05292378
Recruiting
The purpose of the study is to better understand the biological mechanisms of carbon dioxide (CO2)-induced cognitive impairments.
Gender:
ALL
Ages:
Between 18 years and 30 years
Trial Updated:
12/04/2024
Locations: Rutgers - EOHSI, Piscataway, New Jersey
Conditions: Healthy
Register for Updates