There are currently 231 active clinical trials seeking participants for Healthy research studies. The states with the highest number of trials for Healthy participants are California, Florida, Texas and Maryland.
This is a Study to Evaluate the Safety, Tolerability, PK and PD of IV Administered ABL301 in Healthy Adult Participants
NCT05756920
Recruiting
This is a Phase 1, FIH, randomized, double-blind, placebo-controlled study designed to assess the safety, tolerability, PK and PD after SAD and MAD in healthy adult participants.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
02/21/2024
Locations: PPD Development, LP, Austin, Texas
Conditions: Healthy
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Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation
NCT05153395
Recruiting
The purpose of this project is to examine the impact of increases in brain insulin on sympathetic nervous system activity, as well as peripheral and cerebral blood flow in humans.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
02/21/2024
Locations: University of Missouri, Columbia, Missouri
Conditions: Healthy, Vasodilation, Insulin Resistance, Autonomic Dysfunction, Obesity
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Use of Incentives for Stressful Medical Procedures
NCT06254898
Recruiting
The goal of this clinical trial is to learn about the use of incentives in pediatric patients requiring medical procedures. The main questions it aims to answer are: Are incentives effective at reducing pediatric anxiety for medical procedures? What is the best way to use incentives with pediatric populations requiring medical procedures? Participants will be provided support in preparation for their procedure and during the procedure by a child life specialist and might receive an incentive pr... Read More
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
02/20/2024
Locations: Children's Hospital Colorado Anschutz, Aurora, Colorado +2 locations
Conditions: Healthy
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Effects of Sleep Disruption on Drug Response
NCT03680287
Recruiting
The central scientific premise of the proposed study is that sleep disruption (SD) will influence individuals' subjective response to blinded medication administration. The investigators further believe these responses will vary among patients who have chronic low back pain (CLBP) vs. healthy controls, and that sex will moderate effects. The proposed study evaluates whether CLBP patients' subjective responses to study medication administration are altered by SD. The investigators focus on two o... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
02/19/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Low Back Pain, Recurrent, Healthy
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BT-600 Single and Multiple Ascending Oral Doses in Healthy Adult Subjects
NCT06275464
Recruiting
This is a randomized, double-blind, placebo-controlled Phase 1 study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of BT-600 when administered in single and multiple ascending doses to healthy participants. The study will enroll up to 48 participants, with participation lasting 2-3 weeks in addition to up to 28 days (about 4 weeks) for screening. The purposes of this study are to learn about the safety and tolerability of single and multiple rising oral... Read More
Gender:
All
Ages:
Between 19 years and 50 years
Trial Updated:
02/16/2024
Locations: Celerion, Lincoln, Nebraska
Conditions: Healthy
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Expanding Fertility Care to Poor and Low Resourced Settings Study
NCT05205733
Recruiting
The investigators currently lack an understanding of barriers to completing the male factor infertility evaluation. Furthermore, as the investigators continue to expand access to fertility treatment particularly within low-resourced settings, it is important that all aspects of infertility within a couple are equally explored. The COVID-19 pandemic has disproportionately affected low-income communities and communities of color at greater rates in terms of not only disease morbidity/mortality but... Read More
Gender:
Male
Ages:
Between 18 years and 64 years
Trial Updated:
02/15/2024
Locations: University of California San Francisco, San Francisco, California
Conditions: Healthy, Male Infertility, Infertility, Male, Fertility Disorders
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Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane
NCT03930680
Recruiting
The purpose of this research study is to determine whether early administration of Dexrazoxane prevents Doxorubicin induced cardiotoxicity.
Gender:
Female
Ages:
Between 18 years and 65 years
Trial Updated:
02/15/2024
Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas
Conditions: Healthy
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Sex Disparities in Hypoxic Vasodilation and Impact of Obesity
NCT05219799
Recruiting
The purpose of this project is to examine key mechanisms contributing to sex-differences in hypoxic vasodilation and the impact of obesity, with particular emphasis on the sympathetic nervous system.
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
02/15/2024
Locations: University of Missouri, Columbia, Missouri
Conditions: Obesity, Vasodilation, Healthy
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A Study of Invasive Hemodynamic for MACHD Registry
NCT05849025
Recruiting
This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Congenital Heart Disease
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High-resolution Phosphocreatine and Creatine Mapping of Human Muscle and Brain
NCT04234880
Recruiting
In this study, we aim to develop and validate a noninvasive approach for quantifying and imaging energy metabolism, without contrast agents, on widely available clinical MRI scanners. Briefly, this technique allows specific and selective imaging of the energy metabolite phosphocreatine (PCr), in vivo and non-invasively. PCr is one of the predominant high-energy phosphates present in brain and muscle and one that is altered by common diseases. Although energy metabolism and PCr play a vital role... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
02/13/2024
Locations: F. M. Kirby Center and Johns Hopkins University Medical School, Baltimore, Maryland
Conditions: Healthy
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Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes.
NCT03807973
Recruiting
This study will use brain Positron Emission Tomography/ Magnetic Resonance Imaging (PET/MRI) and an investigational radioactive drug called [Zr-89]oxine to track the location of white blood cells (also called leukocytes) in the body. PET/MRI will be used to visualize labeled white blood cells and determine if they enter the central nervous system in conditions associated with brain inflammation (also called neuroinflammation). By better understanding the role of neuroinflammation in fibromyalgia... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/13/2024
Locations: UAB, Birmingham, Alabama
Conditions: Fibromyalgia, Chronic Fatigue Syndrome, Multiple Sclerosis, Healthy
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Assessment of Endogenous Oxalate Synthesis
NCT05229952
Recruiting
This study aims to determine the daily rate of endogenous synthesis of oxalate using carbon 13 oxalate isotope tracer technique and a low-oxalate controlled diet.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/12/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Healthy, Kidney Stone, Obesity
Register for Updates