Illinois is currently home to 2681 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive A Kidney Transplant
Recruiting
The primary objective of the study is to assess adverse events (AEs) and serious adverse events (SAEs) in kidney transplant recipients previously treated with REGN5459 or REGN5458 in the R5459-RT-1944 study. The secondary objectives of the study are to evaluate each of the following in kidney transplant recipients previously treated with REGN5459 or REGN5458: Rates and classification of antibody-mediated and T-cell-mediated kidney allograft rejection Graft survival Allograft function Delayed a... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/29/2024
Locations: Northwestern University Comprehensive Transplant Center, Chicago, Illinois
Conditions: Chronic Kidney Disease (CKD)
Elements Vital to Treat Obesity Study
Recruiting
The overall objective of this study is to evaluate the first rigorously optimized, remotely delivered treatment for obesity against the current gold standard treatment in a head-to-head randomized controlled trial. The investigators will be comparing the previously developed and optimized behavioral weight loss intervention (APP) to the Diabetes Prevention Program (DPP), to evaluate program weight-loss success and cost-effectiveness.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/29/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Obesity
Biology and Benefits of Music Play and Stories for Kids/Parents During ALL Treatment
Recruiting
Music therapy has become a standard palliative care service in many pediatric and adult hospitals; however, a majority of music therapy research has focused on the use of music to improve psychosocial dimensions of health, without considering biological dimensions. This study builds on prior work examining the psychosocial mechanisms of action underlying an Active Music Engagement (AME) intervention, designed to help manage emotional distress and improve positive health outcomes in young childre... Read More
Gender:
All
Ages:
Between 3 years and 8 years
Trial Updated:
05/29/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Acute Lymphoblastic Leukemia, Pediatric, Pediatric Cancer
Understanding How Powered Componentry Impacts K2-Level Transfemoral Amputee Gait
Recruiting
The goal of this study is to understand how providing power at the knee or ankle individually, or providing power at both the knee and ankle, impacts ambulation for K2 level transfemoral amputees. Aim 1: measure functional performance of K2 level ambulators when using a commercially available passive microprocessor knee prosthesis (Ottobock Cleg/Ottobock foot) or a powered knee and ankle prosthesis (SRALab Hybrid Knee and SRAlab Polycentric Powered Ankle. Aim 2: Participants will be evaluated... Read More
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
05/28/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Amputation, Amputation, Traumatic, Amputation of Knee, Amputation; Traumatic, Limb
Pharmacological Inhibition of Lactation After 16 to 20 Week Abortion
Recruiting
The goal of this clinical trial is to compare breast symptoms (lactation, engorgement, etc) of individuals who undergo a procedure for second trimester of pregnancy loss between 16 weeks and 20 weeks gestational age. The participants will be randomly placed in two groups, one with a placebo tablet and one with medication called "cabergoline" which are taken immediately after their procedure. Researchers will compare groups to see if there are any significant differences in breast symptoms.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
05/28/2024
Locations: Northwestern Medical Center, Chicago, Illinois
Conditions: Lactation Suppressed, Second Trimester Abortion
Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials
Recruiting
This trial will study different outreach methods to assess impact on enrollment of underrepresented minorities (specifically African Americans) to early phase cancer clinical treatment trials. Both patients and providers (those seeing enrolled patients) will be enrolled and receive the study interventions or no intervention (control arm).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: University of Chicago Medicine Comprehensive Cancer Center, Chicago, Illinois
Conditions: Cancer, Malignancy, Malignant Neoplasm
Exploring Mechanisms of Massed Cognitive Processing Therapy
Recruiting
The overall goal of this randomized controlled trial with partial crossover is to compare the effectiveness of 1-week virtual massed Cognitive Processing Therapy (CPT) to 5-day virtual relaxation training (RT) with regard to their ability to reduce posttraumatic stress disorder (PTSD) symptoms. Specifically, this study is designed to 1) examine changes in PTSD symptoms during and following the respective intervention, and 2) explore possible psychological treatment mechanisms, including cognitiv... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: Rush University Medical Denter, Chicago, Illinois
Conditions: PTSD
Parkinson's Foundation PD GENEration Genetic Registry
Recruiting
Development of a central repository for PD-related genomic data for future research.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: University of Illinois-Chicago, Chicago, Illinois
Conditions: Parkinson's Disease
Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy
Recruiting
SASS (Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy) will be a multicenter, prospective, randomized, single-blind non-inferiority trial.
Gender:
Female
Ages:
21 years and above
Trial Updated:
05/28/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Stress Urinary Incontinence, Pelvic Floor Disorders
Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia
Recruiting
The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients
Gender:
All
Ages:
Between 5 years and 50 years
Trial Updated:
05/28/2024
Locations: University of Illinois Chicage, Chicago, Illinois
Conditions: Sickle Cell Disease, Renal Disease, Glomerular Disease
Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL
Recruiting
This research study is studying a medication called Venetoclax and a chemotherapy regimen as a possible treatment for Acute Lymphoblastic Leukemia. The drugs involved in this study are: Venetoclax Standard Chemotherapy (which includes cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate, 6-mercaptopurine, etoposide, and cytarabine
Gender:
All
Ages:
18 years and above
Trial Updated:
05/27/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Leukemia
Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Exercise Performance
Recruiting
Heart rate variability (HRV) is a measure of the variation in time between each heartbeat. It is an indirect and ubiquitous biomarker of performance readiness and recovery measured by most consumer-grade wearable fitness trackers. However, there is little documented on the relationship between HRV, training load, and performance measures in the Real-World. Whoop wrist-worn activity trackers have been validated against the gold-standard Electrocardiography (ECG) for HRV and HR measurements. Who... Read More
Gender:
All
Ages:
Between 25 years and 50 years
Trial Updated:
05/24/2024
Locations: PepsiCo R&D, Gatorade Sports Science Institute, Chicago, Illinois
Conditions: Heart Rate Variability, Exercise