Illinois is currently home to 2636 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
NCT03408106
Recruiting
Prospective Clinical Trial of HIV+ Living Donor Kidney Donation for HIV+ Recipients
Gender:
ALL
Ages:
21 years and above
Trial Updated:
09/25/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: HIV Infections
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A Phase 3B Study to Evaluate Bone Mineral Density with Long-Term Use of Relugolix Combination Tablet in Women with Uterine Fibroids or Endometriosis
NCT05862272
Recruiting
The purpose of this clinical trial to characterize changes in bone mineral density during continuous treatment with relugolix combination tablet for up to 48 months (4 years) and 1 year of post-treatment follow-up in premenopausal women with heavy menstrual bleeding associated with uterine leiomyomas (fibroids) or with moderate-to-severe pain associated with endometriosis.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
09/24/2024
Locations: Chicago, Chicago, Illinois
Conditions: Uterine Fibroids, Endometriosis
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Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss
NCT04228978
Recruiting
The PROVE Trial is a randomized clinical trial that will determine whether a weight loss intervention combined with walking exercise achieves greater improvement or less decline in six-minute walk distance at 12 month follow-up than walking exercise alone in people with PAD and BMI\>25 kg/m2. The intervention uses a Group Mediated Cognitive Behavioral framework, connective mobile technology, remote monitoring by a coach, and a calorie restricted Dietary Approaches to Stop Hypertension (DASH)-der... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Peripheral Artery Disease, Overweight or Obesity
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Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
NCT03827694
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
ALL
Ages:
Between 120 days and 21 years
Trial Updated:
09/24/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections
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M6®-C Artificial Cervical Disc Two-Level IDE Pivotal Study
NCT04982835
Recruiting
Prospective, concurrently controlled, multi-center study to evaluate the safety and effectiveness of the Spinal Kinetics M6-C™ artificial cervical disc compared to anterior cervical discectomy and fusion (ACDF) for the treatment of contiguous two-level symptomatic cervical radiculopathy at vertebral levels from C3 to C7 with or without spinal cord compression.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/20/2024
Locations: Carle Health, Urbana, Illinois
Conditions: Cervical Disc Degenerative Disorder
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Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
NCT04095663
Recruiting
The COSMID (Comparison of Surgery and Medicine on the Impact of Diverticulitis) trial is a pragmatic, patient-level randomized superiority trial of elective colectomy vs. best medical management for patients with quality of life (QoL) limiting diverticular disease. A parallel observational cohort will include those who are disinclined to have their treatment choice randomized, but are willing to contribute information about their outcomes. The goal of the COSMID trial is to answer the question:... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/20/2024
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Diverticulitis
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Consent for Use of Stored Patient Specimens for Future Testing
NCT00031408
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Northwestern Univ Med School, Chicago, Illinois
Conditions: HIV Infections
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The Purpose of This Study is to Evaluate the Safety and Efficacy of D-MNA in Adult Patients With Nodular Basal Cell Carcinoma
NCT06608238
Recruiting
The goal of the study is to learn about the safety and how effective two different strengths of D-MNA compared to a placebo (a look-alike substance that contains no drug) in the treatment of nodular basal cell skin cancer
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
09/19/2024
Locations: Site #1, Rolling Meadows, Illinois
Conditions: Nodular Basal Cell Carcinoma
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Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)
NCT06605898
Recruiting
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in middle-aged adults. Our research team will evaluate three different groups: the first group will be chosen using a predictive analytics model that predicts who will benefit most from the MIND diet, the second group will follow the MIND diet without being pre-selected, and the... Read More
Gender:
ALL
Ages:
Between 45 years and 64 years
Trial Updated:
09/18/2024
Locations: University of Illinois at Urbana-Champaign, Urbana, Illinois
Conditions: Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
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Exercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device
NCT06410261
Recruiting
Approximately 50% of people with multiple sclerosis (MS) use a wheelchair within 30 years of the initial diagnosis. Wheelchair use in MS is often associated with fatigue as a consequence of muscle weakness. Indeed, fatigue, a prevalent consequence of MS, often becomes debilitating and exhausts energetic resources when carrying-out tasks of daily life and/or interacting with the community, as these require ambulatory mobility. This experience of excessive fatigue has its roots in muscle weakness... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Multiple Sclerosis
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MBC2OTP Project (Measurement-Based Care Implementation in Community Opioid Treatment Programs)
NCT06345274
Recruiting
The goal of this clinical trial is to evaluate the effectiveness and implementation of measurement-based care, which involves the systematic use of client self-report data to inform and enhance treatment, in opioid treatment programs using a pilot hybrid effectiveness-implementation study design. The main questions this study aims to answer are: 1) is measurement based care effective for improving patient treatment attendance and opioid abstinence, and 2) can measurement based care be implemente... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2024
Locations: Family Guidance Centers, Inc., Aurora, Illinois
Conditions: Opioid Use Disorder
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A Study to Investigate Safety and Tolerability of NDX-3315 and NDX-3324 in Healthy Participants and Patients with Eosinophilic Esophagitis
NCT05757856
Recruiting
An open-label phase 2 study to assess the safety and exploratory diagnostic performance of the oral radiopharmaceutical agent NDX-3315 and NDX-3324 in healthy participants and patients with eosinophilic esophagitis (EoE).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/18/2024
Locations: Northwestern Univerisity, Chicago, Illinois
Conditions: Eosinophilic Esophagitis
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