Illinois is currently home to 2669 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
GU-01: Glycyrrhizin in Prostate Cancer
NCT06378346
Recruiting
This is a pilot, randomized, window-of-opportunity treatment trial in which participants with previously untreated prostate cancer (PCa) who are candidates for surgery (radical prostatectomy)
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: University of Illinois, Chicago, Illinois
Conditions: Prostate Cancer
Register for Updates
CIED Infection Quality Initiative Demonstration Project
NCT05471973
Recruiting
The aim of this Quality Initiative (QI) demonstration project is to develop a model to increase guideline-driven care for patients with cardiovascular implantable electronic devices (CIED) infection. Multidisciplinary teams will be established to carry out the multifaceted intervention. This program seeks to improve early identification and diagnosis, appropriate treatment, and faster time to treatment of CIED infection.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: Northwestern, Chicago, Illinois
Conditions: Infections
Register for Updates
Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: the SOLAR Trial
NCT04883671
Recruiting
The aim of this study is to learn whether the early initiation of a specialized and focused type of radiation called stereotactic body radiation therapy (SBRT) will impact the progression of advanced adenoid cystic carcinoma, quality of life, and overall survival. The name(s) of the study intervention involved in this study is: * Stereotactic Body Radiation Therapy (SBRT)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: Adenoid Cystic Carcinoma, Metastatic Adenoid Cystic Carcinoma
Register for Updates
Fisetin to Reduce Senescence and Mobility Impairment in PAD
NCT06399809
Recruiting
The investigators propose a pilot randomized trial to gather preliminary data to test the hypothesis that Fisetin will reduce abundance of senescent cells in blood, skeletal muscle, and both subcutaneous and inter muscular adipose tissue and improve 6-minute walk distance in 34 people with peripheral artery disease (PAD). the investigators will determine whether greater declines in abundance of cells with senescent markers are associated with greater improvement in 6-minute walk distance in peop... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
10/06/2024
Locations: Northwestern University Feinberg School of Medicine, Chicago, Illinois
Conditions: Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty, Claudication
Register for Updates
Repurposing Dupilumab for Management of Pruritic Genetic Inflammatory Skin Disorders
NCT05649098
Recruiting
Severe itch is a common symptom of many genetic skin disorders and leads to a negative impact on patient quality of life. The investigators hypothesize that: a) intervention with dupilumab will improve itch in patients with pruritic genetic inflammatory skin disorders, even those not recognized to be Th2-driven; and b) the administration of dupilumab will be well-tolerated, regardless of underlying genetic skin disorder. The total clinical study duration will be 26 months (104 Weeks). The treatm... Read More
Gender:
ALL
Ages:
6 months and above
Trial Updated:
10/03/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Skin Diseases
Register for Updates
Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis
NCT05042258
Recruiting
Single center, prospective, Open label study of sleep, pruritus and circadian function pre/post 12-weeks of dupilumab treatment in children 6-17 years old
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
10/03/2024
Locations: Lurie Children's Hospital/Northwestern University, Chicago, Illinois
Conditions: Atopic Dermatitis, Sleep Disturbance
Register for Updates
Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry
NCT06166277
Recruiting
The CNA-FWRD Registry is an international prospective observational multicenter registry of patients with symptomatic vasovagal syncope and bradyarrhythmias managed under routine care by medical therapy and radiofrequency catheter ablation of ganglionated plexi or permanent pacemaker implantation.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
10/02/2024
Locations: Rush University Medical Centert, Chicago, Illinois
Conditions: Vasovagal Syncope, AV Block-2Nd Degree-Type 1, Sinus Pause
Register for Updates
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
NCT05150691
Recruiting
This is a dose-escalation and dose-expansion Phase 1/2a trial to evaluate the safety and tolerability of DB-1303/BNT323 in subjects with advanced solid tumors that express HER2.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/02/2024
Locations: University of Chicago, Chicago, Illinois
Conditions: HER2-positive Advanced Solid Tumor
Register for Updates
Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia
NCT05001828
Recruiting
Pegylated arginine deiminase (ADI-PEG 20) will be combined with venetoclax and azacitidine for treatment of subjects with previously treated or untreated with high risk factor acute myeloid leukemia (AML). Venetoclax and azacitidine are front-line therapy for such patients, and ADI-PEG 20 will be added to this regimen in a phase IA/B study.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
10/02/2024
Locations: Orchard Healthcare Research Inc, Skokie, Illinois
Conditions: Acute Myeloid Leukemia, Adult
Register for Updates
Brain Function Monitoring During Surgery
NCT06619730
Recruiting
The purpose of this research is to gather information on the effectiveness of the Sedline Brain Function Monitor, and its use in this study to determine whether monitoring the brain activity during anesthesia will improve recovery, including earlier discharge and less side effects. Furthermore, the study team wants to determine whether males and females respond to anesthetics in a similar manner with and without brain monitoring.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
10/01/2024
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Surgery
Register for Updates
Comparing Meniscal Repair Biologic Augmentation: Marrow Venting Procedure Versus PRP (MVP Trial)
NCT04775004
Recruiting
There are no current or past RCT comparing biologic augments for meniscal repair. There is good data supporting both the use of BMVP of the intercondylar notch and intra-articular PRP injections for augmentation of meniscal repair. However, the effectiveness of these augmentation methods with respect to each other has never been investigated. The knowledge gained will allow us to potentially influence and adapt protocols to treat this particular patient population. Additionally, resources availa... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
10/01/2024
Locations: University of Chicago Medicine, Chicago, Illinois
Conditions: Meniscal Tear
Register for Updates
SMR Stemless Reverse Vs SMR Reverse Shoulder System
NCT04697004
Recruiting
The SMR Stemless Reverse is intended for total, primary shoulder joint replacement by reducing pain and restoring shoulder articular mobility function. This is a prospective, multi-center, randomized, controlled trial to demonstrate non-inferiority of the SMR Stemless Reverse to the SMR Reverse Shoulder System. Patients with joint dysfunction who continue to experience significant symptoms despite an appropriate course of non-operative management are eligible. Patients will be considered enroll... Read More
Gender:
ALL
Ages:
22 years and above
Trial Updated:
10/01/2024
Locations: Rush Orthopaedics, Chicago, Illinois
Conditions: Arthroplasty, Replacement
Register for Updates