Illinois is currently home to 2636 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Pediatric Anesthesia Quality Improvement Project
NCT00674388
Recruiting
The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent these adverse events.
Gender:
ALL
Ages:
21 years and below
Trial Updated:
11/20/2023
Locations: Children's Memorial Hospital, Chicago, Illinois
Conditions: Surgery, Anesthesia, Children
Register for Updates
SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation
NCT05935384
Recruiting
The purpose of SIBYL is to generate clinical validity data for the ability of a future version of Guardant360 developed by Guardant Health to measure response to systemic therapy in patients with unresectable advanced solid tumors. It is necessary to collect clinical data points and treatment outcomes in order to demonstrate clinical validity for longitudinal monitoring with ctDNA and correlation of ctDNA dynamics with therapeutic response, as evaluated by standard methods, including RECIST 1.1... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: Orchard Healthcare Research Inc., Skokie, Illinois
Conditions: Non-small Cell Lung Cancer, Colorectal Cancer, Breast Cancer
Register for Updates
A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering
NCT04914507
Recruiting
Anterior vertebral body tethering (AVBT) is a novel, minimally invasive, growth modulation technique that was recently approved by the FDA under a Humanitarian Device Exemption (HDE). The goal of AVBT is to control curve progression by applying compression on the convex side of the spine deformity. While there has been great initial enthusiasm about the technique as an alternate treatment option to spinal fusion for skeletally immature children with scoliosis, there is a need to better understan... Read More
Gender:
ALL
Ages:
18 years and below
Trial Updated:
11/14/2023
Locations: Shriners Children's Chicago, Chicago, Illinois
Conditions: Scoliosis Idiopathic
Register for Updates
Evaluation of Correlation Between Oculometric Measures and Clinical Assessment in Parkinson's Disease
NCT05862649
Recruiting
This is a multicenter longitudinal study in about 300 patients with Idiopathic Parkinson's disease, who will be evaluated in several clinical centers with a clinical assessment and an oculometric examination during a time period with specific intervals. This study aims to evaluate the correlation between oculometric measures and clinical assessment over time, as well as the potential to detect early change in clinical status using an oculometric assessment.
Gender:
ALL
Ages:
Between 40 years and 85 years
Trial Updated:
11/13/2023
Locations: Rush University, Chicago, Illinois
Conditions: Parkinson Disease
Register for Updates
Long Term Outcomes Following Hernia Repair With Mesh
NCT04578340
Recruiting
The objective of this study is to establish the extent to which mesh improves quality of life and surgical outcomes following hernia repair.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/11/2023
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: Abdominal Hernia
Register for Updates
Angiotensin II for Distributive Shock
NCT04904562
Recruiting
This is a single-center, randomized, double-blind, placebo-controlled pilot study. A total of 40 patients who develop distributive shock, intra-operatively or post-operatively within 48 hours of heart transplant or left ventricular assist device placement will be enrolled. Participants will be randomized to Angiotensin II (Giapreza) vs. placebo plus standard of care, as a first line agent for vasoplegia. Two groups of patients will be enrolled: * Group A: Heart Transplant (10 control, 10 treatm... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/10/2023
Locations: Northwestern University, Chicago, Illinois
Conditions: Distributive Shock
Register for Updates
The Gut and Skin Microbiome in Vitiligo Disease Progression
NCT03577327
Recruiting
Investigators plan to perform a pilot study that aims to characterize the microbiome of human vitiligo patients with both active and stable disease and compare this to the microbiome of age and sex matched controls. The investigators aim to answer the question whether the gut and skin microbiome of patients with vitiligo differs from the general population.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
11/07/2023
Locations: Northwestern University, Chicago, Illinois
Conditions: Vitiligo, Healthy
Register for Updates
Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy
NCT05004129
Recruiting
This is an open-label phase 2/3 study for individuals with Congenital Myotonic Dystrophy (Congenital DM1) who participated in the preceding AMO-02-MD-2-003 study or individuals with either Congenital or Childhood Onset DM1 who are treatment naïve.
Gender:
ALL
Ages:
Between 6 years and 45 years
Trial Updated:
11/05/2023
Locations: Lurie's Children's Hospital, Chicago, Illinois
Conditions: Congenital Myotonic Dystrophy
Register for Updates
Safety and Efficacy Evaluation of the Mosaic Ultra Device
NCT06117293
Recruiting
Evaluate the Safety and Efficacy of the Mosaic Ultra 1550nm system for the treatment of skin tone and texture, facial rejuvenation, photoaging, wrinkles, scars, stretch marks, acne vulgaris and hair loss.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
11/01/2023
Locations: Advanced Dermatology, Lincolnshire, Illinois
Conditions: Skin Texture Disorder, Photoaging, Wrinkle, Scar, Stretch Mark, Acne Vulgaris, Hair Loss
Register for Updates
Wool Clothing for the Management of Childhood Atopic Dermatitis (DESSINE2)
NCT04011215
Recruiting
The study is a sequentially recruited, cross-over-cohort, outpatient-based evaluation of the effectiveness of wool clothing, as compared to standard clothing, in reducing the severity of childhood atopic dermatitis (eczema) over two consecutive six-week periods.
Gender:
ALL
Ages:
Between 3 months and 5 years
Trial Updated:
10/26/2023
Locations: Northwestern University, Skin Disease Research Center, Lurie Children's Hospital, Chicago, Illinois
Conditions: Dermatitis, Atopic
Register for Updates
Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL
NCT05082519
Recruiting
This study is for older children, adolescents, and young adults with B-cell Acute Lymphoblastic Leukemia (B-ALL). Higher amounts of body fat is associated with resistance to chemotherapy in patients with B-ALL. Chemotherapy during the first month causes large gains in body fat in most people, even those who start chemotherapy at a healthy weight. This study is being done to find out if caloric restriction achieved by a personalized nutritional menu and exercise plan during routine chemotherapy... Read More
Gender:
ALL
Ages:
Between 10 years and 25 years
Trial Updated:
10/25/2023
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: B-cell Acute Lymphoblastic Leukemia, Obesity
Register for Updates
Using Information Technology to Improve Outcomes for Children Living With Cancer
NCT04789720
Recruiting
This proposed study plans to develop and evaluate a patient-oriented, technology-based, symptom monitoring system that reports symptoms experienced by children with cancer to their parents and health care providers.
Gender:
ALL
Ages:
Between 8 years and 17 years
Trial Updated:
10/25/2023
Locations: Ann & Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois
Conditions: Cancer
Register for Updates