Illinois is currently home to 2661 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage
NCT03926624
Recruiting
Phase III, multicenter, randomized study with two arms (1:1 ratio) enrolling patients with AML relapsed/refractory after 2, 3, or 4 prior induction regimens: Experimental arm: DFP-10917 14-day continuous intravenous (IV) infusion at a dose of 6 mg/m²/day followed by a 14-day resting period per 28-day cycles. Control arm: Non-Intensive Reinduction (LoDAC, Azacitidine, Decitabine, Venetoclax Combination Regimens) or Intensive Reinduction (High and Intermediate Dose Cytarabine Regimens), dependin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/18/2022
Locations: Rush University, Chicago, Illinois
Conditions: Leukemia, Myeloid, Acute
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Optimizing Orthodontic Appliances Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms
NCT05573308
Recruiting
The decision on aligner changing is based on orthodontists' personal experience and common knowledge that an approximated time span for the aligner have exhausted its biological efficacy. However, a one size fits all approach is not always ideal, as an average determined time is not taken into account of a patient's individual biological response. The aligners could be progressed earlier than the determined time, or they may stay inactive for a while, waiting for the in-office visit. Dental Moni... Read More
Gender:
All
Ages:
Between 12 years and 70 years
Trial Updated:
10/06/2022
Locations: Orthodontic Specialists of Lake County (Antioch), Antioch, Illinois
Conditions: Malocclusion, Misaligned Teeth
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SVS VQI TransCarotid Revascularization Surveillance Project
NCT02850588
Recruiting
The VQI TCAR Surveillance Project is designed to monitor the safety and effectiveness of stents placed directly into the carotid artery while reversing blood flow within the carotid artery to reduce stroke risk. It will compare this less-invasive surgical procedure with standard carotid endarterectomy in centers that participate in the Society for Vascular Surgery Vascular Quality Initiative.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/05/2022
Locations: Society for Vascular Surgery Patient Safety Organization, Chicago, Illinois
Conditions: Carotid Artery Disease
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Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial
NCT05159765
Recruiting
This is a multi-center, randomized, double-masked clinical trial. All study devices are market approved/cleared in the localities where the study is conducted. Subjects will be randomly assigned to wear NaturalVue Sphere single vision contact lenses (SVCL) or NaturalVue Multifocal (NVMF) soft contact lenses for a total of three years.
Gender:
All
Ages:
Between 7 years and 13 years
Trial Updated:
10/03/2022
Locations: North Suburban Vision Consultants, Deerfield, Illinois
Conditions: Myopia
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Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS®) Real World Outcomes
NCT04725838
Recruiting
The UPGRADE registry will capture long-term, real-world outcomes to understand the effect of Differential Target Multiplexed (DTM®) programming in the Spinal Cord Stimulation (SCS) implanted population on the management of chronic pain, primarily on its use for trunk and/or limb pain. The clinical study is sponsored by Celéri Health and is funded through a financial grant from Medtronic's External Research Program. The registry study will be conducted across approximately 25 centers in the Unite... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/28/2022
Locations: Millennium Pain Center (National Spine and Pain Centers - Bloomington, IL), Bloomington, Illinois
Conditions: Chronic Pain
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OEIS Outcome Data Registry
NCT03058913
Recruiting
This registry is created under the sponsorship of the Outpatient Endovascular and Interventional Society (OEIS) to monitor the clinical course and treatment outcomes of patients undergoing office-based endovascular procedures.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/27/2022
Locations: Outpatient Endovascular Interventional Society (OEIS), Hoffman Estates, Illinois
Conditions: Peripheral Arterial Disease
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Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software
NCT05389072
Recruiting
As new orthokeratology fitting software emerges onto the market, it is of interest to assess their usefulness in guiding eye practitioners with lens fit. The goal of this study is to evaluate the comfort of Paragon orthokeratology lenses when they are fit using the new Procornea software.
Gender:
All
Ages:
Between 6 years and 35 years
Trial Updated:
09/22/2022
Locations: Carillon Vision Care, Glenview, Illinois
Conditions: Myopia
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Effect of Standardization of Urine Collection Using PEEZY Device as Compared to Clean Peezy for DAB
NCT05554081
Recruiting
This study aims specifically to compare the rates of contaminants between standard clean-catch urine collection and urine collected using the PEEZY device. In particular, this study will compare the rates of contamination as stratified by BMI status (i.e., BMI < 30 and BMI ≥30). Based on previous studies through LUHS and the Wolfe lab, we anticipate a reduction in contamination from sample collected using the PEEZY device, particularly among those pregnant women with BMI ≥30. To investigate this... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
09/21/2022
Locations: Loyola University medical Center, Maywood, Illinois
Conditions: Asymptomatic Bacteriuria, Urinary Tract Infections
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Trial of FETO for Severe Congenital Diaphragmatic Hernia
NCT05450653
Recruiting
This is a single site pilot trial to study the feasibility of Fetoscopic Endoluminal Tracheal Occlusion (FETO) therapy in the most severe group of fetuses with congenital diaphragmatic hernia (CDH) at Ann & Robert H. Lurie Children's Hospital of Chicago (Lurie Children's). This procedure aims to increase fetal lung volume before birth and improve survival after birth. This study will enroll 10 pregnant women who meet study criteria.
Gender:
Female
Ages:
18 years and above
Trial Updated:
09/19/2022
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Congenital Diaphragmatic Hernia
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Late Onset Alzheimer's Disease
NCT05010603
Recruiting
The goal of this study is to is to focus on the genetic influences on Alzheimer's Disease (AD) risk. The investigators are looking for families and/or individuals (affected or unaffected) of any ethic background (African American, Caucasian, and Hispanics) with a family history of AD and willing to participate.
Gender:
All
Ages:
55 years and above
Trial Updated:
09/16/2022
Locations: Rush University, Aurora, Illinois
Conditions: Alzheimer Disease
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Envi™-SR Randomized Controlled Trial for Endovascular Treatment of Ischemic Stroke
NCT05107206
Recruiting
The study objective is to examine and compare clinical outcomes, as measured by Modified Rankin Scale (mRS) at 90 days (± 15 days) post treatment, and related performance characteristics of the Envi™-SR and concurrent parallel Control Devices currently cleared by the U.S. FDA for treatment of stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/15/2022
Locations: Advocate Aurora Health, Downers Grove, Illinois
Conditions: Acute Ischemic Stroke
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Rare and Atypical Diabetes Network
NCT05544266
Recruiting
RADIANT is a network of 14 clinical sites and several laboratories dedicated to the study of atypical diabetes. The objective of this study is to define new forms of diabetes and the unique mechanisms underlying these forms of atypical diabetes. The specific aims are to: Identify and enroll individuals and families with undiagnosed rare and atypical forms of diabetes. Determine the etiologic basis of the metabolic disorder among individuals and families with novel forms of rare and atypical di... Read More
Gender:
All
Ages:
All
Trial Updated:
09/14/2022
Locations: University of Chicago, Chicago, Illinois
Conditions: Diabetes Mellitus, Diabetes Mellitus Progression, Glucose Intolerance, Glucose Metabolism Disorders, Metabolic Disease, Endocrine; Complications, Endocrine System Diseases
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