Illinois is currently home to 2669 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Characterization of the Microbiome in Cutaneous T Cell Lymphoma
NCT03932279
Recruiting
Investigators plan to perform a pilot study that aims to characterize the microbiome of human cutaneous T cell lymphoma patients and compare this to the microbiome of age and sex matched controls.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
03/08/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Cutaneous T Cell Lymphoma
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Dietary Supplementation on Gastrointestinal Barrier Function
NCT06262880
Recruiting
The purpose of the current study is to examine the effects of a dietary supplement containing plant derived phenolics at two different dose levels on parameters of gastrointestinal (GI) health in otherwise generally healthy adults with risk factors (high BMI and waist circumference) for increased GI permeability. The primary hypothesis is that supplementation with plant derived phenolics will improve gut health compared to placebo.
Gender:
ALL
Ages:
Between 30 years and 69 years
Trial Updated:
03/06/2024
Locations: Biofortis, Addison, Illinois
Conditions: Intestinal Permeability
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Phase I Study of RiMO-401 With Radiation in Advanced Tumors
NCT06182579
Recruiting
This is a single arm study of RiMO-401 with radiation in patients with advanced tumors. A single escalation dose of RiMO-401 is intratumorally injected in a 3+3 study design to identify the recommended dose.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Advanced Solid Tumor, Intratumoral Injection
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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
NCT05442567
Recruiting
The study is an extension of two parent studies (MLN0002-3024 \[NCT04779307\] and MLN0002-3025 \[NCT04779320\]). Participants must have participated in one of the previous studies. The purpose of this study is to collect the long-term safety of vedolizumab in children with UC or CD.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
03/05/2024
Locations: Advocate Children's Hospital Park Ridge, Park Ridge, Illinois
Conditions: Ulcerative Colitis, Crohn's Disease
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Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery
NCT04885244
Recruiting
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Rush University, Department of Neurosurgery, Chicago, Illinois
Conditions: Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
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Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0
NCT04194996
Recruiting
Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Rush University, Department of Neurosurgery, Chicago, Illinois
Conditions: Cervical Deformity
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Corticospinal Function After Spinal Cord Injury
NCT02451683
Recruiting
The investigator's overall goal is to develop new strategies to test optimization of Spike-timing-dependent plasticity (STDP) doses to maximize strategy to restore upper and lower-limb motor function in individuals with spinal cord injury (SCI). The investigator proposes to use modern electrophysiological methods to enhance the efficacy of residual corticospinal connections. Defining the neural basis by which corticospinal volleys generate muscle responses will provide crucial information requir... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/01/2024
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Spinal Cord Injury
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Effectiveness of Relationship Education for Reducing HIV Incidence Among SGM
NCT05678556
Recruiting
The purpose of this study is to upgrade an existing relationship education and HIV prevention program. This program is designed for gay, bisexual, queer, and transgender and non-binary people who partner with cisgender men. This means the program is designed for gay, bisexual and queer men, including both cisgender and transgender men. It is also designed for transgender and non-binary people who partner with cisgender men, including both transfeminine and transmasculine people. The investigator... Read More
Gender:
ALL
Ages:
Between 16 years and 34 years
Trial Updated:
02/27/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Hiv, Chlamydia, Gonorrhea
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Food Cravings Strategies During Dietary Weight Loss
NCT06280339
Recruiting
The purpose is to optimize the EMPOWER program by integrating strategies to reduce food cravings, a critical yet often overlooked factor for long-term success in weight management. The objective of this study is to determine the efficacy of craving coping strategies on weight loss outcomes by conducting a randomized controlled trial. Participants will be randomized to receive one of the two strategies to manage food cravings.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/26/2024
Locations: Bevier HAll UIUC, Urbana, Illinois
Conditions: Obesity, Food Cravings, Weight Loss
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Testing "SupporT for ADHD and Related Treatment" (START) for Families of Children With ADHD
NCT05796427
Recruiting
The randomized control trial (RCT) study includes 2 aims; one being to test whether START increases access to treatment for ADHD. Investigators believe the intervention group will demonstrate improved treatment engagement and access to all treatments compared to controls. The second aim is to explore whether START leads to functional improvements across home, social and academic domains for the child and family. Investigators believe the intervention group will show better functioning including... Read More
Gender:
ALL
Ages:
Between 6 years and 12 years
Trial Updated:
02/26/2024
Locations: Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois
Conditions: ADHD
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Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
NCT01574053
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Huntington's Disease
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Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration
NCT05657301
Recruiting
VAN-2201 is Phase I clinical trial to assess the safety and tolerability of KH631 in subjects with neovascular AMD. KH631 is gene therapy designed to deliver a protein which targets and blocks VEGF via an adeno-associated viral vector. The standard of care for patients with neovascular AMD are anti-VEGF treaments, which have demonstrated improvement in vision and reduction in fluid. A one time placement of a product which inhibits VEGF has the potential to reduce the patient burden of regular in... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
02/23/2024
Locations: Kanghong Investigative Site, Lemont, Illinois
Conditions: Age-Related Macular Degeneration
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