Illinois is currently home to 2637 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Persea Americana for Total Health (PATH)-2
NCT05941728
Recruiting
The goal of this clinical trial is to learn about the effects of avocado consumption on gastrointestinal health in adults with overweight and obesity. The main questions is aims to answer are: How does avocado consumption affect the gut microbiome? How does avocado consumption affect thinking? Are there connections between the microbiome and cognition? Participants will be asked to eat provided meals with and without avocados for three 4-week periods. At the end of each 4-week period, participa... Read More
Gender:
ALL
Ages:
Between 25 years and 74 years
Trial Updated:
10/11/2023
Locations: University of Illinois, Urbana Champaign, Urbana, Illinois
Conditions: Overweight and Obesity
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Alio WEAR Study: Long-term Wear of the Alio Platform
NCT06056739
Recruiting
The WEAR study is long-term interventional study designed to evaluate patient and clinician use of the Alio platform, per its FDA cleared indications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: Site 1, Huntley, Illinois
Conditions: End Stage Kidney Disease
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Oral Minoxidil for the Treatment of Recurrent Platinum Resistant Epithelial Ovarian Cancer
NCT05272462
Recruiting
The primary purpose of this study is to determine the response rate of patients with recurrent platinum resistant ovarian cancer when treated with oral minoxidil. Secondary objectives include estimating the time to disease progression while on minoxidil and to describe the toxicities of minoxidil when used for patients with recurrent platinum resistant ovarian cancer. An exploratory objective is to evaluate if efficacy of minoxidil is improved in patients that have the Kir6/SUR complex versus th... Read More
Gender:
FEMALE
Ages:
Between 18 years and 90 years
Trial Updated:
10/03/2023
Locations: Loyola University Medical Center, Maywood, Illinois
Conditions: Ovarian Cancer
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An Enhanced Vaginal Dilator to Reduce Radiation-Induced Vaginal Stenosis
NCT03876860
Recruiting
This is a randomized control trial aimed to decreased radiation-induced vaginal stenosis in patients with endometrial or cervical cancer treated with post-operative external beam radiation therapy with or without brachytherapy. The intervention is an enhanced vaginal dilator model, including a silicone band placed at the desired depth of dilator insertion. The new model will be compared against the traditional vaginal dilator model used as our institutional standard of care. We hypothesize the e... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
10/03/2023
Locations: Loyola University Medical Center, Maywood, Illinois
Conditions: Endometrial Cancer, Cervical Cancer, Vaginal Stricture, Radiation Toxicity
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Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP
NCT05620784
Recruiting
Holmium Laser Enucleation of the Prostate (HoLEP) is a size-independent treatment option for benign prostatic hypertrophy (BPH) as recommended by the American Urological Association (AUA) Guidelines. Loop diuretics (furosemide) have been given historically during the morcellation portion of HoLEP to promote urine production in the post-operative setting and to minimize the impact of fluid absorption during long periods of morcellation. The intra-operative use of 20mg IV furosemide in perioperati... Read More
Gender:
MALE
Ages:
Between 18 years and 89 years
Trial Updated:
09/11/2023
Locations: Northwestern University, Chicago, Illinois
Conditions: BPH With Urinary Obstruction, BPH, Hematuria, Same Day Discharge
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Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients
NCT05900427
Recruiting
The purpose of this trial is to compare the difference in the proportion of patients with tolerable pain scores, VAS pain scores, quality of recovery and opioid use in milligram equivalents (at 24, 48, 72, 96 and 120 hours postoperatively) in patients undergoing shoulder arthroplasty who receive interscalene blocks with or without Liposomal Bupivacaine. This is a prospective randomized, double-blinded, controlled trial that will enroll 130 subjects undergoing total shoulder arthroplasty or reve... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
09/08/2023
Locations: NorthShore University HealthSystem, Skokie, Illinois
Conditions: Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty
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Non-Invasive Quantification of Liver Health in NASH (N-QUAN)
NCT04054310
Recruiting
To evaluate, in patients with suspected NASH referred for liver biopsy, the diagnostic performance of CT1 at discriminating those with NAS≥4 \& F≥2 from those without.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
09/07/2023
Locations: RUSH University Medical Center, Chicago, Illinois
Conditions: NASH - Nonalcoholic Steatohepatitis
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Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis
NCT05177107
Recruiting
This is a phase IIa randomized trial designed to evaluate bacteriophage therapy in patients with diabetic foot osteomyelitis.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
09/05/2023
Locations: Podiatry 1st / Gateway Clinical Trials, O'Fallon, Illinois
Conditions: Osteomyelitis, Diabetic Foot Osteomyelitis
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To Determine the Best Feeding Practice in Preterm Infants on Non-invasive Ventilation.
NCT05824377
Recruiting
To evaluate the duration to reach full feeds by comparing continuous gavage feeds versus bolus feeds in preterm infants who are on non-invasive respiratory support (RAM cannula - short binasal prongs).
Gender:
ALL
Ages:
All
Trial Updated:
08/29/2023
Locations: Cook County Helath, Chicago, Illinois
Conditions: Prematurity; Extreme, Feeding Patterns, Ventilator Lung; Newborn
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Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments
NCT04056247
Recruiting
This study will develop an algorithm of identifying patients with stage IV NSCLC and Melanoma who could benefit from cancer treatment they receive.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/25/2023
Locations: Northwest Community Healthcare, Rolling Meadows, Illinois
Conditions: Stage IV Non-small Cell Lung Cancer, Stage IV Small Cell Lung Cancer, Stage III Malignant Melanoma, Stage IV Malignant Melanoma
Register for Updates
A Dose Finding Study to Treat Bone Tumor(s)
NCT06008483
Recruiting
To determine the Maximum Tolerated Dose (MTD) of CycloSam®, Samarium-153-DOTMP (Sm-153-DOTMP), a radiopharmaceutical that delivers radiation to the bone when injected, given as a tandemly administered pair of doses to subjects with one or more solid tumor(s) in the bone or metastatic solid tumors to the bone that are visible on bone scan.
Gender:
ALL
Ages:
Between 15 years and 75 years
Trial Updated:
08/18/2023
Locations: Clinical Trial Site, Chicago, Illinois
Conditions: Bone Cancer, Bone Tumor, Solid Tumor, Metastatic Cancer to the Bone, Metastatic Tumor to the Bone
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IPACK on Early Pain Scores After ACL Reconstruction
NCT05985629
Recruiting
The goal of this clinical trial is to learn whether using an anesthetic technique called IPACK block will control pain after ACL reconstruction surgery. The main questions it aims to answer are: * if participants who receive the IPACK block prior to ACL reconstruction experience less pain after surgery and at 1 day after surgery * if participants who receive the IPACK block prior to ACL reconstruction require less short-term opioid use immediately after surgery and up to one week after surgery.... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/03/2023
Locations: Loyola University Medical Center, Maywood, Illinois
Conditions: Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
Register for Updates