Illinois is currently home to 2627 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Terumo Aortic Global Endovascular Registry
NCT04246463
Recruiting
Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: Loyola University of Chicago (Loyola), Chicago, Illinois
Conditions: Abdominal Aortic Aneurysm, Thoracic Aortic Aneurysm, Surgery
Register for Updates
TRIAD Appendicitis Decision-making Surveys
NCT05887414
Recruiting
While appendectomy has been the main treatment of appendicitis for over 100 years, recent European studies found that, at least among highly selected patients, antibiotics alone can be an effective alternative. Surgeons and patients alike have a difficult time deciding if surgery or antibiotics are the best choice to treat appendicitis. The goal of the TRIAD is to evaluate the patients who are a part of the TRIAD implementation program and assess satisfaction and decisional regret for patients w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Appendicitis
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Curvafix® Intramedullary System for Fixation of Pelvic and Acetabular Fractures, A Post Market Evaluation
NCT05606042
Recruiting
Prospective, single arm, post-market evaluation to evaluate the use and performance of the IM Implant in a post market setting.
Gender:
ALL
Ages:
All
Trial Updated:
06/09/2023
Locations: Memorial Medical Center, Springfield, Springfield, Illinois
Conditions: Pelvic Ring Fracture, Acetabular Fracture, Pelvic Fracture, Pelvic Fracture Acetabulum
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Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study
NCT05291884
Recruiting
This is a prospective, multi-center, single-arm, early feasibility study that aims to evaluate the safety of the Impella BTR™ in adult patients requiring left-ventricular hemodynamic support, and to evaluate the effectiveness of the Impella BTR™ in supporting patients to recovery or their next therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/07/2023
Locations: Northwestern University, Evanston, Illinois
Conditions: Heart Failure, Acute Decompensated Heart Failure
Register for Updates
AMP SCZ® Observational Study: PREDICT-DPACC
NCT05905003
Recruiting
The Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ) is a large international collaboration to develop algorithms using a set of clinical and cognitive assessments, multi-modal biomarkers, and clinical endpoints that can be used to predict the trajectories and outcomes of individuals at clinical high risk (CHR) for psychosis and to advance the testing of pharmacological interventions for CHR individuals in need. The goal is to accurately predict which individuals are likely to remit,... Read More
Gender:
ALL
Ages:
Between 12 years and 30 years
Trial Updated:
06/06/2023
Locations: Northwestern University, Evanston, Illinois
Conditions: Clinical High Risk, Psychosis, Remission, Conversion
Register for Updates
Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias
NCT01060371
Recruiting
Spinocerebellar ataxias (SCA) are genetic neurological diseases that cause imbalance, poor coordination, and speech difficulties. There are different kinds of SCA and this study will focus on types 1, 2,3, and 6 (SCA 1, SCA 2, SCA 3 , also known as Machado-Joseph disease and SCA 6). The diseases are rare, slowly progressive, cause increasingly severe neurological difficulties and are variable across and within genotypes. The purpose of this research study is to bring together a group of experts... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
05/30/2023
Locations: University of Chicago, Chicago, Illinois
Conditions: Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6
Register for Updates
The Impact of a Seated Compact Elliptical Trainer on Individuals With Knee OA
NCT05857605
Recruiting
Exercise is considered the most effective, non-drug treatment for reducing pain and improving movement in patients with osteoarthritis. Diminished muscle strength is a common symptom associated with the onset of knee osteoarthritis. The evidence supports the benefit of exercise therapy, in reducing pain and improving function in subjects with knee OA, however research to date has been unable to quantify the disease-modifying effect of any form of exercise. The primary objective of this study is... Read More
Gender:
ALL
Ages:
Between 50 years and 75 years
Trial Updated:
05/11/2023
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Osteoarthritis, Knee Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Register for Updates
ROSE-Longitudinal Assessment With Neuroimaging
NCT05089331
Recruiting
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of motor and cognitive function at baseline, 6 months after baseline, and 12 months after baseline to determine predictors of recovery, progressive cognitive or functional impairment. The investigators propose to leverage the recruitment, DNA, RNA-seq and baseline advanced neu... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/11/2023
Locations: University of Illinois Chicago, Chicago, Illinois
Conditions: Intracerebral Hemorrhage
Register for Updates
Extended High-frequency Hearing and Speech Perception
NCT05435989
Recruiting
This study examines the effects of low-pass filtering speech on speech perception.
Gender:
ALL
Ages:
Between 19 years and 50 years
Trial Updated:
05/08/2023
Locations: University of Illinois Urbana-Champaign, Champaign, Illinois
Conditions: Low-pass Filtering Speech
Register for Updates
Anti-Inflammatory Milk Matrix
NCT04216004
Recruiting
Obesity is pro-inflammatory, impairs metabolism, and physically limiting. Specifically, muscle in obese persons does not synthesize proteins normally. This further increases metabolic and physical dysfunction. As such, obesity programs should not only focus on weight loss, but muscle metabolic health. Dairy nutrients have anti-inflammatory and anabolic properties, but mostly evaluated in isolation and/or pre-clinical designs. Also, it is unknown if the circulating benefits extend to the muscle.... Read More
Gender:
ALL
Ages:
Between 40 years and 59 years
Trial Updated:
05/08/2023
Locations: Freer Hall, Urbana, Illinois
Conditions: Obesity, Skeletal Muscle, Inflammation
Register for Updates
Comprehensive Care Community and Culture Study
NCT04489693
Recruiting
This randomized trial is evaluating whether socioeconomically disadvantaged Medicare patients at increased risk of hospitalization experience fewer hospitalization if those patients are offered care in: 1) ACCT, where patients receive care from different physicians in the hospital and the clinic settings and have access to nurse and social worker care coordination services, 2) CCP where patients receive care from one physician in the inpatient and outpatient settings or 3) C4P which adds screeni... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/03/2023
Locations: David Meltzer, Chicago, Illinois
Conditions: Comprehensive Care, Quality of Care, Medicare, Cost of Care
Register for Updates
Impact of Different Exercise Programs on Knee OA
NCT05844124
Recruiting
This study will examine and compare the changes in serum biomarkers, joint kinematics, and thigh muscle strength based on three different 8-week exercise protocols in individuals with knee pathology: Lower-body positive-pressure (LBPP) supported low-load treadmill walking and Aquatic exercise program and standard of care treadmill or community walking. Investigators hypothesize that both the 8-week exercise programs which aim to partially off-load the knee joint will be associated with a signif... Read More
Gender:
ALL
Ages:
Between 50 years and 75 years
Trial Updated:
05/02/2023
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Osteoarthritis, Knee Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Register for Updates