Illinois is currently home to 2669 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Robotic Mechanical Coring for the Treatment of Moderate to Severe Facial Wrinkles
NCT05091788
Recruiting
This study is a prospective, up to 4 center study of the safety and efficacy of mechanical coring with skin closure of cored holes, intended for the improvement in the appearance of wrinkles of the cheeks in up to 70 subjects after two treatments.
Gender:
ALL
Ages:
Between 22 years and 75 years
Trial Updated:
01/24/2024
Locations: DeNova Research, Chicago, Illinois
Conditions: Wrinkle
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A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: NASH - Nonalcoholic Steatohepatitis
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MANAGE-AF Registry -MANAGEment of Atrial Fibrillation Outcomes Registry (MANAGE-AF)
NCT05978466
Recruiting
The purpose of this research is to learn more about the normal care of patients with a new or pre-existing diagnosis of atrial fibrillation (AF). These abnormal and irregular heartbeats place patients at increased risk of developing clots in their bloodstream that could potentially lead to stroke. Normal care is designed to help prevent this from happening and to lessen or eliminate the symptoms patients may have. There are many different types of AF as well as numerous ways in which a variety o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/17/2024
Locations: CorVita Science Foundation (NFP), Chicago, Illinois
Conditions: Atrial Fibrillation
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Transdermal Optical Imaging (TOI) as a Non-invasive Measure to Detect Changes in Hydration Status in Healthy Adults and Athletes
NCT06212518
Recruiting
The primary objective of this study is to analyze smart phone-based Transdermal Optical Imaging (TOI) features to develop a model that can discern hydration status, including: 1) at various timepoints throughout a 24-hour period in healthy adults from the general population (GENPOP), and 2) before and after a team coach-led training session in athletes competing in a sport (ATHLETE). TOI data will be collected alongside standard reference measures of hydration status. In this study each subject... Read More
Gender:
ALL
Ages:
Between 14 years and 65 years
Trial Updated:
01/13/2024
Locations: PepsiCo R&D Gatorade Sports Science Institute, Chicago, Illinois
Conditions: Dehydration
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BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer
NCT06085742
Recruiting
This is a non-randomized, single arm phase 2 trial of oral CMC based on conversion of doses that would be delivered with conventional metronomic CMF chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/10/2024
Locations: University of Illinois, Chicago, Illinois
Conditions: Breast Cancer
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Coflex PS3 Actual Conditions for Use Study
NCT02555280
Recruiting
A 2 and 5 year evaluation of clinical outcomes in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with additional stabilization using the coflex® Interlaminar Technology for FDA Actual Conditions of Use Study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: 01L_Northshore University Health System, Evanston, Illinois
Conditions: Spinal Stenosis Lumbar
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Aspire2B Personalization Pilot Study Program
NCT06191822
Recruiting
This non-randomized pilot study program is focused on assessing the technical characteristics of the Aspire2B mobile device application.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/02/2024
Locations: Remote, no facility visits. Managed by PepsiCo R&D Life Sciences, Chicago, Illinois
Conditions: App Proficiency, Behavior, Lifestyle
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Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology
NCT03481010
Recruiting
At present, it is not clear whether performing a hip arthroscopy at the same time as a PAO improves patient outcomes after surgery compared to a PAO alone. This research project will randomize patients to receive either a PAO alone, or a PAO and a hip arthroscopy at the same time.
Gender:
ALL
Ages:
Between 16 years and 50 years
Trial Updated:
01/02/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: Hip Dysplasia
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BlueWind RENOVA iStim™ System for the Treatment of OAB
NCT03596671
Recruiting
The OASIS study is prospective, interventional, multi-center study to evaluate the safety and efficacy of the BlueWind RENOVA iStim™ implantable tibial neuromodulation System for the treatment of patients diagnosed with overactive bladder.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
12/29/2023
Locations: Comprehensive Urologic Care, Lake Barrington, Illinois
Conditions: Treatment of Patients Suffering From Overactive Bladder (OAB)
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A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
NCT04775485
Recruiting
FIREFLY-1 is an ongoing, Phase 2, multi center, open-label study to evaluate the safety and efficacy of oral pan-RAF inhibitor DAY101 in pediatric, adolescent, and young adult patients with recurrent or progressive low-grade glioma or an advanced solid tumor harboring a known RAF alteration.
Gender:
ALL
Ages:
Between 6 months and 25 years
Trial Updated:
12/21/2023
Locations: Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Low-grade Glioma, Advanced Solid Tumor
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Open Nipple Sparing Mastectomy (NSM)
NCT04447339
Recruiting
This is retrospective, multicenter chart review is to evaluate the complication rates of prophylactic open NSM procedures through 42 days postoperatively
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/17/2023
Locations: NorthShore University Health System, Evanston, Illinois
Conditions: Nipple Sparing Mastectomy
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TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery
NCT04197687
Recruiting
This phase II trial studies how well TPIV100 and sargramostim work in treating patients with HER2 positive, stage II-III breast cancer that has residual disease after chemotherapy prior to surgery. It also studies why some HER2 positive breast cancer patients respond better to chemotherapy in combination with trastuzumab and pertuzumab. TPIV100 is a type of vaccine made from HER2 peptide that may help the body build an effective immune response to kill tumor cells that express HER2. Sargramostim... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: Illinois CancerCare-Peoria, Peoria, Illinois
Conditions: Breast Adenocarcinoma, Stage II Breast Cancer AJCC v6 and v7, Stage IIA Breast Cancer AJCC v6 and v7, Stage IIB Breast Cancer AJCC v6 and v7, Stage III Breast Cancer AJCC v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7
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