Illinois is currently home to 2668 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Efficacy of Azelastine and Mometasone Irrigation in Comparison to Nasal Sprays in Patients With Chronic Rhinitis
NCT05626621
Recruiting
The goal of this clinical trial is to determine the best combination of drugs and drug delivery routes to treat surgically naive chronic rhinitis patients. The main question it aims to answer is: Do high volume, high pressure delivery mechanisms in nasal irrigation improve the efficacy of azelastine combined with nasal steroid mometasone as compared to the standard low pressure, low volume delivery mechanisms in nasal sprays? Subjects will complete six months of one of three medication regimen... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/25/2023
Locations: Northshore University HealthSystem, Evanston, Illinois
Conditions: Chronic Rhinitis
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Mechanistic Characterization of Uterine Pain
NCT04145518
Recruiting
There are limited treatment options for management of dysmenorrhea, and the physiological processes they affect are not completely understood. For example, NSAIDs are effective in reducing menstrual pain in some women by inhibition of prostaglandin synthesis, but whether those effects are mediated by affecting contractility, perfusion, or hypoxemia is unknown. Understanding how these drugs relieve menstrual pain (and why they fail) would be of substantial clinical significance. Given the foregoi... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
07/19/2023
Locations: NorthShore University HealthSystem, Evanston, Illinois
Conditions: Dysmenorrhea (Disorder), Dysmenorrhea Primary, Dysmenorrhea Secondary, Endometrial Diseases, Leiomyoma, Fibroid Uterus
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Telehealth Implementation of Brain-Computer Interface
NCT05951556
Recruiting
Determine if Telehealth intervention can allow/empower a caregiver (who is untrained) to effectively implement and utilize a Brain-Computer Interface for communication with a participant who is "Locked in" following progression of Amyotrophic Lateral Sclerosis and other conditions.
Gender:
ALL
Ages:
Between 16 years and 100 years
Trial Updated:
07/18/2023
Locations: ShirleyRyan AbilityLab, Chicago, Illinois
Conditions: Amyotrophic Lateral Sclerosis, Stroke
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Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort
NCT05855876
Recruiting
The purpose of this study is to examine measures of GrimAge clock in SOF members undergoing treatment for PTSD/TBI using CSB.
Gender:
ALL
Ages:
Between 40 years and 60 years
Trial Updated:
07/13/2023
Locations: Stella Center, Westmont, Illinois
Conditions: Post-Traumatic Stress Disorder, Traumatic Brain Injury
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Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast
NCT04009044
Recruiting
This phase II trial studies how well topical afimoxifene works in treating patients with breast cancer who have undergone radiation therapy on one breast. Topical afimoxifene is a quick-drying medicated gel that may block the growth of breast cancer cells when applied to the breast skin. The purpose of this research is to determine what effect, if any, differences in skin type between women have on the delivery of topical afimoxifene to the breast tissue, and whether radiation affects the delive... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/12/2023
Locations: Northwestern University, Chicago, Illinois
Conditions: Cancer Survivor, Ductal Breast Carcinoma In Situ, Invasive Breast Carcinoma
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Simple Bone Cysts in Kids
NCT02193841
Recruiting
Simple bone cysts (SBCs) are cysts filled with fluid that occur most frequently in the long bones (arms or legs) of children. There are many ways to treat SBCs but it is unclear if one is better than another. The purpose of this research trial is to compare the effectiveness of two common treatments that are used by surgeons today.
Gender:
ALL
Ages:
Between 2 years and 21 years
Trial Updated:
07/10/2023
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Bone Cyst
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Metoclopramide in Upper Gastrointestinal Bleed
NCT05746377
Recruiting
The goal of this clinical trial is to test if metoclopramide can improve effectiveness of endoscopic intervention in upper gastrointestinal (GI) bleeds. The main questions the investigators hope to answer is Does metoclopramide lessen the need for repeat endoscopy, interventional radiology intervention or surgery in cases of upper GI bleed? Does metoclopramide improve visibility of the GI walls in cases of upper GI bleed?
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/09/2023
Locations: Javon Bea Hospital-Riverside - MercyHealth, Rockford, Illinois
Conditions: Upper GI Bleeding, Bleeds Gastric, Bleed Ulcer, Hemorrhage Gastric, Hemorrhage; Ulcer
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Assessing the Efficacy and Safety fo DEXTENZA, Sustained Release Dexamethasone 0.4 mg Insert(s) for the Treatment of Pain, Inflammation, and Cystoid Macular Edema Following 27 Gauge Vitrectomy With Internal Limiting Membrane Peel for the Treatment of Retinal Edema Associated With Macular Pucker.
NCT04501367
Recruiting
Assessing the efficacy and safety of DEXTENZA, sustained release dexamethasone 0.4 mg inserts following 27 gauge vitrectomy with internal limiting membrane peel
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/27/2023
Locations: Kovach Eye Institute, Elmhurst, Illinois
Conditions: Vitrectomy, Macular Pucker, Retinal Edema
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Electromagnetic Fields Versus Placebo For Child-Pugh A and B Patients With Advanced Hepatocellular Carcinoma
NCT04797884
Recruiting
The primary goals of this study are to compare overall survival and quality of life in subjects with Child-Pugh A or B advanced hepatocellular carcinoma when treated with a device emitting radiofrequencies modulated at specific frequencies or with a device emitting unmodulated radiofrequencies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/25/2023
Locations: Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois
Conditions: Hepatocellular Carcinoma
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Azithromycin to Improve Latency in Exam Indicated Cerclage Control Trial
NCT05132829
Recruiting
Azithromycin is an antibiotic that is effective against bacteria that been associated with preterm birth (PTB). The purpose of this study is to evaluate if the addition of azithromycin prior to exam indicated cerclage prolongs gestation. A cerclage is a suture placed in the cervix to prolong gestation.
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
06/23/2023
Locations: Northwestern University, Chicago, Illinois
Conditions: Preterm Birth, Obstetric Labor, Premature, Obstetric Labor Complications, Pregnancy Complications, Physiological Effects of Drugs, Uterine Cervical Incompetence, Anti-Bacterial Agents, Azithromycin, Cefazolin
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Effects of 4-AP on Functional SCI Recovery
NCT05447676
Recruiting
The purpose of this study is to test a strategy to potentiate functional recovery of lower limb motor function in individuals with spinal cord injury (SCI). The FDA approved drug, Dalfampridine (4-AP). 4-AP will be used in combination of Spike-timing-dependent plasticity (STDP) stimulation and STDP stimulation with limb training.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
06/19/2023
Locations: Shirley Ryan Abilitylab, Chicago, Illinois
Conditions: Spinal Cord Injury
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Terumo Aortic Global Endovascular Registry
NCT04246463
Recruiting
Multi-arm, multi-center, open label, prospective observational registry designed to obtain safety and performance data on the use of CE marked and custom Terumo Aortic endovascular grafts.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/19/2023
Locations: Loyola University of Chicago (Loyola), Chicago, Illinois
Conditions: Abdominal Aortic Aneurysm, Thoracic Aortic Aneurysm, Surgery
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