Illinois is currently home to 2681 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Chicago, Peoria, Springfield and Urbana. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents
NCT04290754
Recruiting
PATH (Promoting AdolescenT Health) 2 Purpose is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT) and Teens Achieving Mastery over Stress (TEAMS), to intervene early to prevent depressive illness and potentially other common mental health disorders. Using cluster randomization, 564 participants eligible for the study will be offered one of two diff... Read More
Gender:
All
Ages:
Between 13 years and 19 years
Trial Updated:
06/28/2022
Locations: UI Health, Chicago, Illinois
Conditions: Depression
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Repetitive Acute Intermittent Hypoxia for Spinal Cord Repair
NCT03433599
Recruiting
Our goal is to enhance repeated exposure to acute intermittent hypoxia (rAIH)/training-induced aftereffects on upper and lower limb function recovery in humans with chronic spinal cord injury (SCI).
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/28/2022
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Spinal Cord Injuries
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Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy
NCT03394365
Recruiting
The purpose of this study is to determine the clinical benefit and characterize the safety profile of tabelecleucel for the treatment of Epstein-Barr virus-associated post-transplant lymphoproliferative disease (EBV+ PTLD) in the setting of (1) solid organ transplant (SOT) after failure of rituximab and rituximab plus chemotherapy or (2) allogeneic hematopoietic cell transplant (HCT) after failure of rituximab.
Gender:
All
Ages:
All
Trial Updated:
06/23/2022
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago (Adults and Pediatrics), Chicago, Illinois
Conditions: Epstein-Barr Virus+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD), Solid Organ Transplant Complications, Lymphoproliferative Disorders, Allogeneic Hematopoietic Cell Transplant, Stem Cell Transplant Complications
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Spasticity After Spinal Cord Injury
NCT04393922
Recruiting
Very often, people who have a SCI have difficulty doing things with their arms or hands as a result of muscle stiffness , or spasticity. Spastacity can cause problems performing even the simplest of everyday tasks. This research will help us understand how the body recovers and changes neurologically after SCI.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/20/2022
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Spinal Cord Injuries
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Droplet-BC Screening Test for the Detection of Breast Cancer, the DROPLET-BC Study
NCT04671498
Recruiting
This study investigates if a new type of test called Droplet-BC screening test can classify breast cancer patients from non-cancer volunteers by circulating small-noncoding RNA in the blood with a statistical validity. This study also investigates if this test can classify the subgroup of breast cancer patients with a variety of conditions. Information from this study may provide a new method of breast cancer screening/diagnosis
Gender:
All
Ages:
18 years and above
Trial Updated:
06/15/2022
Locations: Northwestern University Feinberg School of Medicine, Chicago, Illinois
Conditions: Breast Carcinoma
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Video Education and Behaviour Contract to Optimize Adherence in Renal Transplants
NCT03540121
Recruiting
This study aims to test the effectiveness of an electronic-based video intervention and behavioral contract on improving medication adherence among kidney transplant recipients.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/26/2022
Locations: University of Illinois Health Sciences System, Chicago, Illinois
Conditions: Kidney Transplantation, Medication Adherence
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Non-Guided vs. Guided Surgery to Immediately Loaded PrimeTaper Implants in Partially Edentulous Patients
NCT05264545
Recruiting
A 510k approved dental device for subjects requiring single or multiple tooth replacement with implants where immediate restoration/loading is preferred.
Gender:
All
Ages:
25 years and above
Trial Updated:
05/25/2022
Locations: Periodontal Medicine Surgical Specialists, LLC, Oakbrook Terrace, Illinois
Conditions: Partially Edentulous Maxilla or Mandible
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Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma
NCT02847559
Recruiting
The purpose of this research study is to determine the effects bevacizumab (the study drug) combined with Optune (the study device) tumor treatment field therapy has on meningiomas. Bevacizumab is considered investigational because the US Food and Drug Administration (FDA) has not approved its use for the treatment of meningiomas. The study drug is a medication that blocks the growth of new blood vessels. It is thought that the study drug may interfere with the growth of new blood vessels and th... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/25/2022
Locations: Northwestern University, Chicago, Illinois
Conditions: Anaplastic (Malignant) Meningioma, Atypical Meningioma, Grade II Meningioma, Grade III Meningioma, Recurrent Meningioma, Supratentorial Meningioma
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Utilization of a Videoscope in Periodontal Regeneration
NCT05275192
Recruiting
Clinical and preclinical studies confirm that regeneration of supporting tissues of teeth lost due to periodontal disease can be achieved using the principles of minimally invasive surgery (MIS). Although this therapeutic approach is well established in clinical settings and can rescue teeth with poor or questionable prognosis, MIS approaches often suffer from lack of predictability due to poor intraoral visibility of the bony lesion and inability to confirm thorough removal of etiological facto... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/24/2022
Locations: University of Illinois, Chicago, College of Dentistry, Periodontics, Chicago, Illinois
Conditions: Chronic Periodontitis
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Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing
NCT04564729
Recruiting
This will be a randomized controlled clinical trial in patients who have undergone primary unilateral total knee arthroplasty at Brigham and Women's Faulkner Hospital, Brigham and Women's Hospital and University of Chicago Medical Center. Study subjects will receive either a shared decision aid (SDA) about pain management or standard of care at the time of discharge. The impact of the SDA on the number of leftover opioid pills on postoperative day 30 and average NRS pain score on postoperative d... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/23/2022
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Knee Arthroplasty, Total, Analgesia, Opioid Use, Unspecified
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Dipraglurant (ADX48621) for the Treatment of Patients With Parkinson's Disease Receiving Levodopa-based Therapy
NCT04857359
Recruiting
This study is designed to evaluate the safety and efficacy of dipraglurant in PD patients with dyskinesia (randomized 1:1 to receive active or placebo) for 12 weeks (1 week at 150 mg per day and 11 weeks at 300 mg per day). The primary efficacy assessment will be based on the Unified Dyskinesia Rating Scale (UDysRS). Patients who complete the 12-week blinded treatment period may have the option to roll into an open-label safety extension study for an additional 12-month treatment period.
Gender:
All
Ages:
Between 30 years and 85 years
Trial Updated:
05/18/2022
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Parkinson Disease, Dyskinesia, Drug-Induced, Dyskinesias
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Patient Navigators for Children's Community Mental Health Services in High Poverty Urban Communities
NCT05294042
Recruiting
The purpose is to study a model of mental health navigation for African American and Latinx children (5-12 years) in high poverty urban communities focused on reducing key parental attitudinal barriers to care. Reducing persistent racial and ethnic disparities in children's mental health is a national priority and patient navigation is a highly promising approach that is rarely used in children's mental health services. The study will examine the effectiveness of paraprofessional (PP) navigators... Read More
Gender:
All
Ages:
Between 5 years and 12 years
Trial Updated:
05/17/2022
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Community Mental Health Services
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