Massachusetts is currently home to 3199 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis
NCT06431373
Recruiting
The purpose of this study is to determine the safety and efficacy of brepocitinib in participants with active, non-anterior (intermediate, posterior, or pan) non-infectious uveitis (NIU).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/25/2024
Locations: Clinical Trial Site, Boston, Massachusetts
Conditions: Uveitis, Posterior, Uveitis, Intermediate, Uveitis
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Skilled Nursing Facility Care At Home
NCT06416670
Recruiting
We will perform a parallel-group multicenter patient-level randomized controlled evaluation of skilled nursing facility care at home. Patients typically referred to a skilled nursing facility following hospitalization will be eligible for enrollment. Instead of admission to a skilled nursing facility, participants will receive care from a technology-enabled team in their own homes or will be allocated to receive care in a traditional skilled nursing facility setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/25/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Skilled Nursing Facility, Rehabilitation
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Study of Single Doses of SBT777101 in Subjects With Rheumatoid Arthritis
NCT06201416
Recruiting
This study will test the safety and effects of SBT777101 when given as a single dose to subjects with rheumatoid arthritis. It is the first study of this treatment being done in humans. Increasing dose levels will be given after the safety at lower dose levels is shown.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
11/25/2024
Locations: Tufts University, Boston, Massachusetts
Conditions: Rheumatoid Arthritis
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KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children with Intestinal Failure
NCT05879835
Recruiting
A multi-site, randomized, 2-arm open-label trial to determine if 4% Tetrasodium (EDTA) catheter lock solution is more effective than heparin lock (standard of care) in preventing central venous catheter occlusions in children with intestinal failure (IF) on total parenteral nutrition (TPN).
Gender:
ALL
Ages:
Between 4 weeks and 18 years
Trial Updated:
11/25/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Pediatric Intestinal Failure
Register for Updates
Telemedicine Intervention in Patients With Chronic Pain in PD
NCT05410392
Recruiting
Pain is a very common and disabling symptom in Parkinson's disease, yet it is often untreated. This study will assess the impact of home-based physical and cognitive exercise interventions to reduce pain in this disease. This approach would offer an easily implemented and affordable way to encourage and maintain use of these interventions by patients virtually indefinitely through remote access technology. The study findings may help VA clinicians provide optimal care for the many Veterans with... Read More
Gender:
ALL
Ages:
Between 40 years and 89 years
Trial Updated:
11/25/2024
Locations: VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts
Conditions: Parkinson's Disease
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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
NCT04916210
Recruiting
The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke. The purpose of the study is to help doctors identify patients at risk for dementia (decline in memory, thinking and other mental abilities that significantly affects daily functioning) after their stroke so that future treatments may be developed to improve outcomes in stroke patients. For this study, a "stroke... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/25/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Dementia, Vascular, Mild Cognitive Impairment, Vascular Cognitive Impairment
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Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration
NCT04523194
Recruiting
The purpose of this collaboration is to establish a multi-modality image database including coronary angiograms, optical coherence tomography (OCT), computed tomography angiograms (CTA) and cardiac magnetic resonance imaging (CMR) for future studies. The main goal of this collaboration is to create a resource to promote further understanding of the pathobiology of atherosclerosis through image analysis.
Gender:
ALL
Ages:
All
Trial Updated:
11/25/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Atherosclerosis
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Cognitive Control to Boost Physical Activity Adherence
NCT06338774
Recruiting
This trial is designed to develop and test the efficacy of cognitive training strategies to improve self-regulatory capacities for middle-aged adults to adopt and sustain a physically active lifestyle. The main questions it aims to answer are: * Can cognitive training designed to improve cognitive control improve physical activity adherence? * What are the psychological, physiological, cognitive, and sociodemographic factors that affect the impact of cognitive control on physical activity adher... Read More
Gender:
ALL
Ages:
Between 40 years and 65 years
Trial Updated:
11/23/2024
Locations: Center for Cognitive and Brain Health, Boston, Massachusetts
Conditions: Physical Inactivity
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Motivation for Exercise: a Mood-Based Focus
NCT06706180
Recruiting
The goal of this study is to assess the effects of an exercise-related video on exercise motivation and adherence. Specifically, the researchers are studying whether an exercise-for-mood video increase levels of exercise motivation as compared to an exercise-for-fitness video.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/22/2024
Locations: Boston University, Boston, Massachusetts
Conditions: Exercise Motivation
Register for Updates
Working Memory Training for People Aging with HIV
NCT06699927
Recruiting
The present study investigates the feasibility of working memory training in people aging with HIV (PAWHIV). In a cross-over design this stage 1 feasibility trial, will evaluate acceptability, and estimate possible effect sizes related to working memory training by examining potential differential effects in PAWHIV and those aging without HIV. This project highlights the importance of tailored cognitive assessments and interventions, engaging with underrepresented communities to enhance inclusiv... Read More
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
11/22/2024
Locations: Northeastern University, Boston, Massachusetts
Conditions: Cognitive Change
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Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System
NCT06157567
Recruiting
This is a non-randomized, multi-center, open-label clinical trial evaluating clinical feasibility treatments with the Profound Matrix system.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/22/2024
Locations: Candela Institue for Excellence, Marlborough, Massachusetts
Conditions: Skin Laxity, Wrinkle, Skin Condition
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Prehospital Telemedicine Feasibility/Acceptability Pilot
NCT05967624
Recruiting
Teleconsultation, or the use of video telecommunications technology to deliver expert recommendations for care remotely, has been used to improve the safety and quality of emergency care for children in hospital-based acute care settings by providing real-time access to remote pediatric physician experts. Whether extending teleconsultation as a patient safety intervention to emergency medical systems (EMS) outside hospitals can similarly benefit sick and injured children in the community is unkn... Read More
Gender:
ALL
Ages:
17 years and below
Trial Updated:
11/22/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Respiratory Distress Syndrome
Register for Updates