Massachusetts is currently home to 3199 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies
NCT06003101
Recruiting
The goal of this clinical trial is to assess the effect of PRP/PPP/BMAC application on functional outcomes after hip arthroscopy to address acetabular labral pathologies. The main questions it aims to answer are: 1. Does PRP/PPP/BMAC application improve functional outcomes after hip arthroscopy to address acetabular labral pathologies? 2. Does PRP/PPP/BMAC application reduce the arthritic burden as measured by functional outcomes following hip arthroscopy to address labral pathologies with conc... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Acetabular Labrum Tear, Femoro Acetabular Impingement, Chondral Defect, Bone Marrow Aspirate Concentrate
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REACH-Es: Adapting a Digital Health Tool to Improve Diabetes Medication Adherence Among Latino Adults
NCT06000813
Recruiting
Latino individuals, the fastest growing ethnic minority population in the United States, have a higher prevalence of type 2 diabetes and diabetes-related complications, and are more likely to report inconsistent use of diabetes medications than non-Hispanic White individuals. The proposed project will test an interactive text message-based tool tailored to address barriers to taking diabetes medications that are relevant to Latino adults. If found feasible, acceptable, and usable, this intervent... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2024
Locations: Massachusetts General Hospital Diabetes Research Center, Boston, Massachusetts
Conditions: Type 2 Diabetes (Adult Onset), Medication Adherence
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NeuroPathways Intervention for Brain Tumor Patients
NCT05976490
Recruiting
This goal of this study is to test an information and support intervention for patients with malignant (or "high-grade") brain tumors. This study was developed to help patients cope after a brain tumor diagnosis. The main question this study aims to answer is whether this intervention (which includes access to an information guide and one-on-one coaching sessions) is feasible (i.e., possible to carry out) and acceptable (i.e., considered helpful) to patients. Participants will be asked to take p... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2024
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Malignant Brain Tumor, Glioma, Coping Skills
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A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes
NCT05956834
Recruiting
The primary objective of this study is to enroll an observational cohort of approximately 60 patients with PSP over the course of 24 months using a multicenter study design and to follow each of them for 12 months. The secondary objective of this study is to develop a robust solution for multi-modal remote monitoring of motor symptoms and function in PSP that can be applied to other Frontotemporal lobar degeneration (FTLD) syndromes.
Gender:
ALL
Ages:
Between 40 years and 89 years
Trial Updated:
11/18/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: PSP, CBD, Progressive Supranuclear Palsy, FTD, Corticobasal Degeneration, Frontotemporal Dementia, Frontotemporal Lobar Degeneration
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Modulation of Brain Oscillations Underlying Working Memory
NCT05923606
Recruiting
This study will use novel transcranial alternating current stimulation (tACS) protocols and electroencephalography (EEG) to modulate and measure brain oscillations that underlie working memory. tACS is a noninvasive method used to modulate the timing and patterns of brain rhythms via weak electric currents passed through electrodes on the scalp.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
11/18/2024
Locations: Martinos Center for Biomedical Imaging, Charlestown, Massachusetts
Conditions: Working Memory
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Lung Cancer Screening in High-risk Black Women
NCT05898594
Recruiting
The goal of this research study is to study U.S. Black women with a history of smoking to examine the feasibility, acceptability, and performance of low-dose computed tomography (LDCT) screening among this population. The name of the intervention used in this research study is: Low-dose computed tomography (radiologic scan) chest scan
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
11/18/2024
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Lung Cancer, Lung Carcinoma
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I Can Move with Purpose Now! a Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients
NCT05842603
Recruiting
The goal of this study is to see if patients with myeloproliferative disorders are able to successfully complete the Cardiac Lifestyle Program(CLP). The goal of the CLP is to teach patients how to become more active and eat healthier foods. The name of the intervention used in this research study is: Cardiac Lifestyle Program (a 12-week, tailored nutrition and physical activity program)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Myeloproliferative Disorders, Leukemia
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BXCL701 Phase 1 R/R Acute Myeloid Leukemia or Myelodysplastic Syndrome
NCT05703542
Recruiting
The goal of this research study is to find the safest and most effective dose of the study drug, BXCL701, for the treatment of Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS). The names of the study drugs involved in this study are/is: * BXCL701
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2024
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome With Excess Blasts-2
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Gastric Assessment of Pediatric Patients Undergoing Surgery
NCT05674643
Recruiting
The goal of this pilot prospective cohort study is to examine the reproducibility of gastric volume and emptying as measured by gastric ultrasound and its correlation to a gold-standard test for gastric emptying in the perioperative period in pediatric patients. The main questions it aims to answer are: * What is the reliability (inter-rater variability between expert and novice assessors, and intra-rater variability) of a) the gastric antral cross-sectional area (CSA) and b) gastric volume usi... Read More
Gender:
ALL
Ages:
Between 2 years and 18 years
Trial Updated:
11/18/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Fasting, Delayed Gastric Emptying, Aspiration Pneumonia, Respiratory Aspiration of Gastric Content
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Pressure-enabled Delivery in Radioembolization (TriNav Study)
NCT05128032
Recruiting
The purpose of the study is to determine if the type of catheter used in the mapping procedure prior to radioembolization improves the delivery of radioactivity to tumor(s) in participants with liver cancer. The name of the devices involved in this study are: * Pressure Enabled Drug Delivery (PEDD)/TriNav Infusion System * Standard 2.4F microcatheter, not otherwise specified
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2024
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Liver Cancer, Hepatocellular Carcinoma, Metastatic Colorectal Cancer
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Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery
NCT04912531
Recruiting
Patients who undergo cardiothoracic surgery often experience pain and anxiety around the time of surgery. Currently, treatments for pain and anxiety around the time of surgery include opioids and benzodiazepines, which can have severe side effects and can be ineffective. Interventions combining virtual reality with olfactory stimuli are a promising alternative to opioids and benzodiazepines in the treatment of pain and anxiety around the time of surgery. The aim of this study is to evaluate the... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Postoperative Pain, Anxiety Postoperative, Opioid Use
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The Role of Wearable Devices in Cardiothoracic Surgery: Predicting and Detecting Early Postoperative Complications
NCT04824066
Recruiting
The overarching goal of this research is to use machine learning analysis of high-resolution data-collected by wearable technology-of cardiothoracic surgical patients to assess recovery and detect complications at their earliest stage
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/18/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Surgery--Complications
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