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Massachusetts Paid Clinical Trials
A listing of 3199 clinical trials in Massachusetts actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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Clinical Trial Phase
Massachusetts is currently home to 3199 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Recruiting
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As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
FUSION: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS)
Recruiting
The primary purpose of this study is to evaluate the efficacy of ION363 on clinical function and survival in carriers of fused in sarcoma mutations with amyotrophic lateral sclerosis (FUS-ALS).
Gender:
ALL
Ages:
10 years and above
Trial Updated:
11/08/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Amyotrophic Lateral Sclerosis
Isatuximab, Lenalidomide, Bortezomib, and Dexamethasone in NDMM
Recruiting
This research is testing whether the investigational drug isatuximab is safe and effective when used in combination with standard agents for the treatment of newly diagnosed multiple myeloma.
Gender:
ALL
Ages:
75 years and above
Trial Updated:
11/08/2024
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Multiple Myeloma, Newly Diagnosed Multiple Myeloma (NDMM), Autologous Stem Cell Transplant
A Study to Investigate the Efficacy and Safety of NSI-8226 in Adults with Eosinophilic Esophagitis
Recruiting
Phase 2 study to evaluate the safety, tolerability, PK, immunogenicity, and pharmacodynamics of solrikitug in adult participants with eosinophilic esophagitis.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/07/2024
Locations: Research Site 1004, Boston, Massachusetts
Conditions: Eosinophilic Esophagitis (EoE)
Clinical and Basic Investigations Into Congenital Disorders of Glycosylation
Recruiting
The purpose of this research is to study the natural history of congenital disorders of glycosylation and its causes and treatments.
Gender:
ALL
Ages:
All
Trial Updated:
11/07/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Congenital Disorders of Glycosylation
Real-world Patient Reported Outcomes Among Patients Treated With Camzyos
Recruiting
This real-world study will assess changes in health status among participants with symptomatic obstructive hypertrophic cardiomyopathy who are treated with mavacamten in the real world.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/06/2024
Locations: Analysis Group Inc., Boston, Massachusetts
Conditions: Obstructive Hypertrophic Cardiomyopathy
A Text Messaging Intervention to Reduce Perinatal Depression Risk
Recruiting
Development and preliminary testing of a text messaging intervention that will reduce the risk of a major depressive episode and worsening depressive symptoms in perinatal individuals. The system will screen pregnant individuals, send tailored text messages with links to enhanced content, and will include a peer chat function.This accessible text platform will leverage both the ease of use inherent in text messages and the power of enhanced content drawn evidence from based behavioral interventi... Read More
Gender:
FEMALE
Ages:
Between 16 years and 45 years
Trial Updated:
11/06/2024
Locations: UMass Chan Medical School, Worcester, Massachusetts
Conditions: Major Depressive Episode
Improving Memory in Alzheimer's Disease with Noninvasive Brain Stimulation
Recruiting
The investigators will evaluate the theory that Alzheimer's disease-related memory impairment derives from the inefficient orchestration of rhythmic activity at the level of large-scale cortical networks. The results as expected to elucidate AD-related pathophysiology and set groundwork for the development of drug-free interventions for improving memory in AD and related dementias.
Gender:
ALL
Ages:
Between 50 years and 100 years
Trial Updated:
11/06/2024
Locations: 677 Beacon St. Room 308, Boston, Massachusetts
Conditions: Alzheimer Disease
Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields
Recruiting
The participants are being treated with Tumor Treating Fields (TTFields) for malignant glioma, and this type of treatment may cause skin-related side effects. This study will test whether using clindamycin and triamcinolone topical lotions can prevent skin-related side effects of TTFields.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/06/2024
Locations: Tufts Medical Center, Boston, Massachusetts
Conditions: Glioblastoma, Skin Toxicity, Recurrent Glioblastoma
CraniSeal Post Approval Study
Recruiting
To collect post-approval data comparing the safety and effectiveness of CraniSeal Dural Sealant to DuraSeal Dural Sealant. The study has been powered specifically to determine whether the CraniSeal device when used as an adjunct to sutured dural closure following elective cranial surgery is no worse than (i.e., non-inferior) to the DuraSeal device with respect to proportion of subjects free from post-operative cerebrospinal fluid (CSF) leaks. Additional safety outcomes (i.e., surgical site infec... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/05/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Leak, Cerebrospinal Fluid
A Randomized Clinical Trial of a Novel Drug Education and Diversion Program (iDECIDE) for Middle and High School Students
Recruiting
The primary goal of this study is to test the effectiveness of the iDECIDE (Drug Education Curriculum: Intervention, Diversion, and Empowerment) curriculum, a novel drug education and diversion program, in approximately 300 middle and high school students, who have violated their school substance use policies in the past month, as an alternative to punitive school responses for school-based substance use infractions. This randomized controlled trial will test the hypothesis that adolescents rand... Read More
Gender:
ALL
Ages:
Between 9 years and 22 years
Trial Updated:
11/05/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Substance Use, Harm Reduction, Adolescent Behavior
Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer
Recruiting
The goal of this study is to find the best way to help participants and families manage the stress of facing a serious illness and be better able to "bounce back" or be resilient after a difficult situation. Participants will take part in the "Promoting Resilience in Stress Management" PRISM program, which is designed to provide skills to change or improve the impact of stress in everyday life.
The name of the intervention used in this research study is:
-PRISM (a mobile app program comprised... Read More
Gender:
ALL
Ages:
Between 12 years and 25 years
Trial Updated:
11/05/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Stress, Anxiety
Improving Hallucinations by Targeting the RSTS with TES
Recruiting
Hallucinations are a core diagnostic feature of psychotic disorders. They involve different sensory modalities, including auditory, visual, olfactory, tactile, and gustatory hallucinations, among others. Hallucinations occur in multiple different neurological and psychiatric illnesses and can be refractory to existing treatments. Auditory hallucinations and visual hallucinations are found across diagnostic categories of psychotic disorders (schizophrenia, schizoaffective, bipolar disorder). Desp... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
11/05/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Hallucinations, Auditory, Psychosis