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Massachusetts Paid Clinical Trials
A listing of 3150 clinical trials in Massachusetts actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
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Clinical Trial Phase
Massachusetts is currently home to 3150 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Boston, Worcester, Springfield and Burlington. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Type 2 Diabetes Clinical Trial
Recruiting
Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.
Conditions:
Type 2 Diabetes
Diabetes Mellitus Type 2 in Obese
Diabetes Type Two
Type 2 Diabetes Mellitus
Diabete Type 2
Featured Offer
Lose Weight with GLP-1 Medications
Recruiting
Policy Lab has partnered with CareGLP to offer trusted access to GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.
As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.
Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD
Recruiting
This is a Prospective, Non-interventional, Multicenter, Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients with Neovascular (Wet) Age-related Macular Degeneration (nAMD). All subject who completed the parent clinical study (NCT06213038 and NCT05986864) will undergo safety and efficacy assessments up to 5 years post study drug injection.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
04/03/2024
Locations: Ophthalmic Consultants of Boston, Boston, Massachusetts
Conditions: Neovascular (Wet) Age-related Macular Degeneration
Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas
Recruiting
This research is being done to assess the effectiveness and safety of acalabrutinib combined with lisocabtagene maraleucel (liso-cel) for people with relapsed/refractory aggressive B-cell lymphoma.
This research study involves the study drug acalabrutinib in combination with lisocabtagene maraleuce
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Refractory Aggressive B-cell Lymphomas, Refractory B-Cell Non-Hodgkin Lymphoma, Aggressive B-cell NHL, Diffuse Large B-cell Lymphoma (DLBCL), De Novo or Transformed Indolent B-cell Lymphoma, DLBCL, Nos Genetic Subtypes, T Cell/Histiocyte-rich Large B-cell Lymphoma, EBV-Positive DLBCL, Nos, Primary Mediastinal [Thymic] Large B-cell Lymphoma (PMBCL), High-Grade B-Cell Lymphoma, Nos, C-MYC/BCL6 Double-Hit High-Grade B-Cell Lymphoma, Grade 3b Follicular Lymphoma, C-MYC/BCL2 Double-Hit High-Grade B-Cell Lymphoma
A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care
Recruiting
The overall objective of this study is to conduct a randomized effectiveness-implementation trial to test the non-inferiority of tele-Brief Behavioral Treatment for Insomnia vs. tele-Cognitive-Behavioral Therapy for Insomnia among socioeconomically disadvantaged adults with insomnia in the primary care setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/02/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Insomnia
Treating Leg Symptoms in Women With X-linked Adrenoleukodystrophy
Recruiting
The investigators recently observed that up to 25% of women with X-linked adrenoleukodystrophy (ALD) have moderate to severe Restless Leg Syndrome (RLS). In this study, the investigators aim to estimate the prevalence of RLS among women with ALD and to assess whether pramipexole improves RLS symptoms as well as sleep and gait measures in women with ALD.
Gender:
FEMALE
Ages:
Between 18 years and 75 years
Trial Updated:
04/02/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Adrenoleukodystrophy, Restless Legs Syndrome
Gait Analysis in Neurological Disease
Recruiting
The purpose of this study is to investigate whether speed-dependent measures of gait can be identified in patients with neurological conditions that affect gait, particularly in subjects with parkinsonian disorders.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/02/2024
Locations: Clinical Research Center BIDMC, Boston, Massachusetts
Conditions: Parkinson's Disease, Parkinsonian Disorders, Atypical Parkinson Disease, Progressive Supranuclear Palsy, Multiple System Atrophy, Corticobasal Degeneration, Gait, Frontal, Huntington Disease
Ultrasound Guided Femoral Nerve Block
Recruiting
The goal of the study is to evaluate whether pain control achieved by Ultrasound Guided Femoral Nerve Blockade (USFNB) is equal in efficacy to standard pain management practice of parenteral injection of opioid pain medication in patients presenting to the emergency department (ED) with hip fracture.
Gender:
ALL
Ages:
Between 18 years and 101 years
Trial Updated:
04/02/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Hip Fracture
Hematoma Block for Distal Radius Fracture
Recruiting
The purpose of this study is to determine the efficacy of ultrasound guided hematoma block versus traditional "blind" hematoma block for analgesia in distal radius fracture reduction.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
04/02/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Distal Radius Fracture
Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)
Recruiting
In this study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in modulating aberrant neurocognitive processes implicated in pediatric patients with obsessive compulsive disorder (OCD).
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
04/01/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Pre-exposure Prophylaxis (PrEP) for Health
Recruiting
This randomized controlled trial will test the efficacy of "PrEP for Health," a behavioral intervention to improve the use of antiretroviral pre-exposure prophylaxis (PrEP) among at-risk people who inject drugs (PWID) in two syringe service program (SSP) settings in Lawrence and Boston/Cambridge, Massachusetts. The investigators will equally randomize 200 PWID to receive either (a) the "PrEP for Health" intervention condition involving theory-informed HIV and PrEP education, motivational intervi... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/01/2024
Locations: AIDS Action, Cambridge, Massachusetts
Conditions: Substance Dependence, HIV (Human Immunodeficiency Virus)
The BENeFiTS Trial in Beta Thalassemia Intermedia
Recruiting
Beta-thalassemias and hemoglobinopathies are serious inherited blood diseases caused by abnormal or deficiency of beta A chains of hemoglobin, the protein in red blood cells which delivers oxygen throughout the body.The diseases are characterized by hemolytic anemia, organ damage, and early mortality without treatment. Increases in another type of (normal) hemoglobin, fetal globin (HbF), which is normally silenced in infancy, reduces anemia and morbidity. Even incremental augmentation of fetal g... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/01/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Beta Thalassemia Intermedia, Sickle Cell Disease
Hereditary Risk Factors for Thyroid Cancer
Recruiting
Thyroid cancers can occur sporadically, but can also be found as tumors that cluster in families with other cancers or genetic syndromes. Researchers are studying thyroid cancer in children and families, with a particular interest in understanding genes and other factors that may put individuals at risk for developing thyroid cancer and thyroid nodules.
* In this study, family and medical history information is collected alongside a blood or saliva sample for genetic studies.
* Individuals with... Read More
Gender:
ALL
Ages:
All
Trial Updated:
04/01/2024
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Thyroid Cancer
COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER
Recruiting
This is research study is assessing the effects of 6-g daily use of freeze-dried instant coffee on liver fat and fibrosis and the gut microbiome and metabolome in patients who have completed routine treatment (including surgery, chemotherapy and radiotherapy) for stage I-III colorectal cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/29/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Colorectal Cancer, Coffee, Gastrointestinal Microbiome, Stenosis, Fibrosis, Liver, Ultrasound Elastography, Proton Magnetic Resonance Spectroscopy